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Pip5kl1 phosphatidylinositol-4-phosphate 5-kinase-like 1 [ Mus musculus (house mouse) ]

Gene ID: 227733, updated on 12-Aug-2019

Summary

Official Symbol
Pip5kl1provided by MGI
Official Full Name
phosphatidylinositol-4-phosphate 5-kinase-like 1provided by MGI
Primary source
MGI:MGI:2448520
See related
Ensembl:ENSMUSG00000046854
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
BC028795
Expression
Biased expression in testis adult (RPKM 5.8), cortex adult (RPKM 2.5) and 6 other tissues See more
Orthologs

Genomic context

See Pip5kl1 in Genome Data Viewer
Location:
2; 2 B
Exon count:
12
Annotation release Status Assembly Chr Location
108 current GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (32575226..32583783)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (32431339..32439299)

Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 102, member A Neighboring gene RIKEN cDNA 9430097D07 gene Neighboring gene dolichol-phosphate (beta-D) mannosyltransferase 2 Neighboring gene ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 Neighboring gene uncharacterized LOC115489513 Neighboring gene U6 spliceosomal RNA Neighboring gene ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
1-phosphatidylinositol-4-phosphate 5-kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
ATP binding IEA
Inferred from Electronic Annotation
more info
 
kinase activity IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
phosphatidylinositol phosphate kinase activity IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
negative regulation of cell migration ISO
Inferred from Sequence Orthology
more info
 
negative regulation of mitochondrial membrane potential ISO
Inferred from Sequence Orthology
more info
 
negative regulation of protein phosphorylation ISO
Inferred from Sequence Orthology
more info
 
phosphatidylinositol metabolic process IEA
Inferred from Electronic Annotation
more info
 
phosphorylation IEA
Inferred from Electronic Annotation
more info
 
positive regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cell projection IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytosol ISO
Inferred from Sequence Orthology
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
phosphatidylinositol 4-phosphate 5-kinase-like protein 1
Names
PI(4)P 5-kinase-like protein 1
PIPKH
phosphatidylinositol phosphate kinase homolog
ptdIns(4)P-5-kinase-like protein 1
NP_937834.1
XP_006498024.1
XP_017172886.1
XP_017172887.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_198191.3NP_937834.1  phosphatidylinositol 4-phosphate 5-kinase-like protein 1

    See identical proteins and their annotated locations for NP_937834.1

    Status: VALIDATED

    Source sequence(s)
    AL928710, AY376879
    Consensus CDS
    CCDS15920.1
    UniProtKB/Swiss-Prot
    Q6U7H8
    Related
    ENSMUSP00000051282.7, ENSMUST00000055304.13
    Conserved Domains (1) summary
    pfam01504
    Location:129389
    PIP5K; Phosphatidylinositol-4-phosphate 5-Kinase

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p6 C57BL/6J

Genomic

  1. NC_000068.7 Reference GRCm38.p6 C57BL/6J

    Range
    32575226..32583783
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017317397.2XP_017172886.1  phosphatidylinositol 4-phosphate 5-kinase-like protein 1 isoform X1

  2. XM_017317398.2XP_017172887.1  phosphatidylinositol 4-phosphate 5-kinase-like protein 1 isoform X2

  3. XM_006497961.3XP_006498024.1  phosphatidylinositol 4-phosphate 5-kinase-like protein 1 isoform X3

    Conserved Domains (1) summary
    pfam01504
    Location:74334
    PIP5K; Phosphatidylinositol-4-phosphate 5-Kinase
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