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Snapc4 small nuclear RNA activating complex, polypeptide 4 [ Mus musculus (house mouse) ]

Gene ID: 227644, updated on 14-Aug-2019

Summary

Official Symbol
Snapc4provided by MGI
Official Full Name
small nuclear RNA activating complex, polypeptide 4provided by MGI
Primary source
MGI:MGI:2443935
See related
Ensembl:ENSMUSG00000036281
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
5730436L13Rik
Expression
Ubiquitous expression in ovary adult (RPKM 8.1), genital fat pad adult (RPKM 7.7) and 28 other tissues See more
Orthologs

Genomic context

See Snapc4 in Genome Data Viewer
Location:
2; 2 A3
Exon count:
25
Annotation release Status Assembly Chr Location
108 current GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (26362765..26380661, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (26218285..26236173, complement)

Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene G-protein signalling modulator 1 (AGS3-like, C. elegans) Neighboring gene uncharacterized LOC115489442 Neighboring gene DNL-type zinc finger Neighboring gene caspase recruitment domain family, member 9 Neighboring gene endosome associated trafficking regulator 1 Neighboring gene peptidase (mitochondrial processing) alpha Neighboring gene inositol polyphosphate-5-phosphatase E

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • MGC59524

Gene Ontology Provided by MGI

Function Evidence Code Pubs
DNA binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
snRNA transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
snRNA transcription by RNA polymerase III ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
nucleus IEA
Inferred from Electronic Annotation
more info
 
snRNA-activating protein complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
snRNA-activating protein complex subunit 4
Names
SNAPc subunit 4
snRNA-activating protein complex 190 kDa subunit
snapc4

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001290419.1NP_001277348.1  snRNA-activating protein complex subunit 4 isoform b

    See identical proteins and their annotated locations for NP_001277348.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) includes an additional exon in the 5' region, and it thus differs in its 5' UTR and initiates translation at a downstream in-frame start codon, compared to variant 1. The encoded isoform (b) is shorter at the N-terminus, compared to isoform a.
    Source sequence(s)
    AL732541, BC057031
    UniProtKB/Swiss-Prot
    Q8BP86
    Conserved Domains (5) summary
    smart00717
    Location:311358
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd00167
    Location:365406
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam13921
    Location:314374
    Myb_DNA-bind_6; Myb-like DNA-binding domain
    cl09111
    Location:110162
    Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
    cl21498
    Location:172215
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
  2. NM_172339.4NP_758842.1  snRNA-activating protein complex subunit 4 isoform a

    See identical proteins and their annotated locations for NP_758842.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the shorter transcript but encodes the longer isoform (a).
    Source sequence(s)
    AK077522, AL732541, BF466823
    Consensus CDS
    CCDS15802.1
    UniProtKB/Swiss-Prot
    Q8BP86
    Related
    ENSMUSP00000041767.4, ENSMUST00000035427.10
    Conserved Domains (5) summary
    smart00717
    Location:401448
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd00167
    Location:455496
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam13921
    Location:404464
    Myb_DNA-bind_6; Myb-like DNA-binding domain
    cl09111
    Location:200252
    Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
    cl21498
    Location:262305
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p6 C57BL/6J

Genomic

  1. NC_000068.7 Reference GRCm38.p6 C57BL/6J

    Range
    26362765..26380661 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030249751.1XP_030105611.1  snRNA-activating protein complex subunit 4 isoform X10

  2. XM_030249740.1XP_030105600.1  snRNA-activating protein complex subunit 4 isoform X5

    Related
    ENSMUSP00000109750.2, ENSMUST00000114115.8
  3. XM_006497903.4XP_006497966.1  snRNA-activating protein complex subunit 4 isoform X4

    Conserved Domains (5) summary
    smart00717
    Location:409456
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd00167
    Location:463504
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam13921
    Location:412472
    Myb_DNA-bind_6; Myb-like DNA-binding domain
    cl09111
    Location:208260
    Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
    cl21498
    Location:270313
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
  4. XM_011239065.3XP_011237367.1  snRNA-activating protein complex subunit 4 isoform X2

    Conserved Domains (5) summary
    smart00717
    Location:409456
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd00167
    Location:463504
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam13921
    Location:412472
    Myb_DNA-bind_6; Myb-like DNA-binding domain
    cl09111
    Location:208260
    Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
    cl21498
    Location:270313
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
  5. XM_011239064.3XP_011237366.1  snRNA-activating protein complex subunit 4 isoform X1

    Conserved Domains (5) summary
    smart00717
    Location:409456
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd00167
    Location:463504
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam13921
    Location:412472
    Myb_DNA-bind_6; Myb-like DNA-binding domain
    cl09111
    Location:208260
    Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
    cl21498
    Location:270313
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
  6. XM_030249744.1XP_030105604.1  snRNA-activating protein complex subunit 4 isoform X7

  7. XM_030249765.1XP_030105625.1  snRNA-activating protein complex subunit 4 isoform X12

  8. XM_030249762.1XP_030105622.1  snRNA-activating protein complex subunit 4 isoform X12

  9. XM_011239066.3XP_011237368.1  snRNA-activating protein complex subunit 4 isoform X3

    Conserved Domains (5) summary
    smart00717
    Location:401448
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd00167
    Location:455496
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam13921
    Location:404464
    Myb_DNA-bind_6; Myb-like DNA-binding domain
    cl09111
    Location:200252
    Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
    cl21498
    Location:262305
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
  10. XM_030249743.1XP_030105603.1  snRNA-activating protein complex subunit 4 isoform X6

  11. XM_011239067.3XP_011237369.1  snRNA-activating protein complex subunit 4 isoform X6

    Conserved Domains (5) summary
    smart00717
    Location:311358
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd00167
    Location:365406
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam13921
    Location:314374
    Myb_DNA-bind_6; Myb-like DNA-binding domain
    cl09111
    Location:110162
    Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
    cl21498
    Location:172215
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
  12. XM_011239069.3XP_011237371.1  snRNA-activating protein complex subunit 4 isoform X9

    See identical proteins and their annotated locations for XP_011237371.1

    Conserved Domains (5) summary
    smart00717
    Location:249296
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd00167
    Location:303344
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam13921
    Location:252312
    Myb_DNA-bind_6; Myb-like DNA-binding domain
    cl09111
    Location:48100
    Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
    cl21498
    Location:110153
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
  13. XM_011239070.3XP_011237372.1  snRNA-activating protein complex subunit 4 isoform X9

    See identical proteins and their annotated locations for XP_011237372.1

    Conserved Domains (5) summary
    smart00717
    Location:249296
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd00167
    Location:303344
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam13921
    Location:252312
    Myb_DNA-bind_6; Myb-like DNA-binding domain
    cl09111
    Location:48100
    Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
    cl21498
    Location:110153
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
  14. XM_011239071.2XP_011237373.1  snRNA-activating protein complex subunit 4 isoform X9

    See identical proteins and their annotated locations for XP_011237373.1

    Conserved Domains (5) summary
    smart00717
    Location:249296
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd00167
    Location:303344
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam13921
    Location:252312
    Myb_DNA-bind_6; Myb-like DNA-binding domain
    cl09111
    Location:48100
    Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
    cl21498
    Location:110153
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
  15. XM_011239068.2XP_011237370.1  snRNA-activating protein complex subunit 4 isoform X8

    Conserved Domains (5) summary
    smart00717
    Location:262309
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd00167
    Location:316357
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam13921
    Location:265325
    Myb_DNA-bind_6; Myb-like DNA-binding domain
    cl09111
    Location:61113
    Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
    cl21498
    Location:123166
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
  16. XM_030249755.1XP_030105615.1  snRNA-activating protein complex subunit 4 isoform X11

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