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Zscan12 zinc finger and SCAN domain containing 12 [ Mus musculus (house mouse) ]

Gene ID: 22758, updated on 26-Sep-2022

Summary

Official Symbol
Zscan12provided by MGI
Official Full Name
zinc finger and SCAN domain containing 12provided by MGI
Primary source
MGI:MGI:1099444
See related
Ensembl:ENSMUSG00000036721 AllianceGenome:MGI:1099444
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Zfp96; FPM315; zfp-96; mKIAA0426; 2510038J07Rik
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in early conceptus; genitourinary system; and thymus primordium. Orthologous to human ZSCAN12 (zinc finger and SCAN domain containing 12). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in CNS E11.5 (RPKM 3.4), testis adult (RPKM 3.3) and 25 other tissues See more
Orthologs
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Genomic context

See Zscan12 in Genome Data Viewer
Location:
13; 13 A3.1
Exon count:
5
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (21546982..21556472)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (21362820..21372302)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene nuclear encoded tRNA methionine 13 (anticodon CAT) Neighboring gene olfactory receptor family 2 subfamily B member 28 Neighboring gene zinc finger with KRAB and SCAN domains 3 Neighboring gene microRNA 6942 Neighboring gene piggyBac transposable element derived 1 Neighboring gene RIKEN cDNA 4930470G03 gene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
zinc finger and SCAN domain-containing protein 12
Names
zinc finger protein 96

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_016684.2NP_057893.2  zinc finger and SCAN domain-containing protein 12

    See identical proteins and their annotated locations for NP_057893.2

    Status: VALIDATED

    Source sequence(s)
    AK075886, AK129138, AK135506, AK142005, BP759768
    Consensus CDS
    CCDS26273.1
    UniProtKB/Swiss-Prot
    Q8R0D8, Q9Z1D7
    UniProtKB/TrEMBL
    Q6ZQB8, Q8C6D3
    Related
    ENSMUSP00000153548.2, ENSMUST00000225545.2
    Conserved Domains (4) summary
    smart00431
    Location:42148
    SCAN; leucine rich region
    COG5048
    Location:231437
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:271291
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:446466
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    21546982..21556472
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030247246.2XP_030103106.1  zinc finger and SCAN domain-containing protein 12 isoform X1

    UniProtKB/Swiss-Prot
    Q8R0D8
    Related
    ENSMUSP00000058904.7, ENSMUST00000053293.14
    Conserved Domains (4) summary
    smart00431
    Location:42148
    SCAN; leucine rich region
    COG5048
    Location:231437
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:271291
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:446466
    zf-H2C2_2; Zinc-finger double domain
  2. XM_006516660.3XP_006516723.1  zinc finger and SCAN domain-containing protein 12 isoform X1

    See identical proteins and their annotated locations for XP_006516723.1

    UniProtKB/Swiss-Prot
    Q8R0D8, Q9Z1D7
    Conserved Domains (4) summary
    smart00431
    Location:42148
    SCAN; leucine rich region
    COG5048
    Location:231437
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:271291
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:446466
    zf-H2C2_2; Zinc-finger double domain