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Cdnf cerebral dopamine neurotrophic factor [ Mus musculus (house mouse) ]

Gene ID: 227526, updated on 5-Mar-2024


Official Symbol
Cdnfprovided by MGI
Official Full Name
cerebral dopamine neurotrophic factorprovided by MGI
Primary source
See related
Ensembl:ENSMUSG00000039496 AllianceGenome:MGI:3606576
Gene type
protein coding
RefSeq status
Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Armetl1; 9330140G23
Predicted to enable growth factor activity. Predicted to be involved in dopaminergic neuron differentiation and neuron projection development. Predicted to be located in extracellular region. Predicted to be active in endoplasmic reticulum and extracellular space. Is expressed in several structures, including brain; genitourinary system; hemolymphoid system gland; salivary gland; and skeletal muscle tissue. Orthologous to human CDNF (cerebral dopamine neurotrophic factor). [provided by Alliance of Genome Resources, Apr 2022]
Biased expression in heart adult (RPKM 3.1), bladder adult (RPKM 1.3) and 12 other tissues See more
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Genomic context

2 A1; 2 1.99 cM
Exon count:
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (3514102..3527413)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (3513065..3526376)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene heat shock protein 14 Neighboring gene predicted gene, 54099 Neighboring gene Myb/SANT DNA binding domain containing 7 Neighboring gene STARR-positive B cell enhancer ABC_E272 Neighboring gene NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2 pseudogene Neighboring gene LSM7 homolog, U6 small nuclear RNA associated pseudogene

Genomic regions, transcripts, and products


  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a


GeneRIFs: Gene References Into Functions

What's a GeneRIF?



Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2)  1 citation
  • Endonuclease-mediated (3) 

General gene information


Clone Names

  • MGC129430

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables growth factor activity IEA
Inferred from Electronic Annotation
more info
enables molecular_function ND
No biological Data available
more info
Process Evidence Code Pubs
involved_in dopaminergic neuron differentiation IBA
Inferred from Biological aspect of Ancestor
more info
involved_in neuron projection development IBA
Inferred from Biological aspect of Ancestor
more info
Component Evidence Code Pubs
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info

General protein information

Preferred Names
cerebral dopamine neurotrophic factor
ARMET-like protein 1
arginine-rich, mutated in early stage tumors-like 1
conserved dopamine neurotrophic factor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177647.4NP_808315.1  cerebral dopamine neurotrophic factor precursor

    See identical proteins and their annotated locations for NP_808315.1

    Status: VALIDATED

    Source sequence(s)
    AL732620, AL929080
    Consensus CDS
    ENSMUSP00000046297.3, ENSMUST00000036350.3
    Conserved Domains (1) summary
    Armet; Degradation arginine-rich protein for mis-folding

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J


  1. NC_000068.8 Reference GRCm39 C57BL/6J

    GenBank, FASTA, Sequence Viewer (Graphics)