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Zcchc2 zinc finger, CCHC domain containing 2 [ Mus musculus (house mouse) ]

Gene ID: 227449, updated on 30-Apr-2024

Summary

Official Symbol
Zcchc2provided by MGI
Official Full Name
zinc finger, CCHC domain containing 2provided by MGI
Primary source
MGI:MGI:2444114
See related
Ensembl:ENSMUSG00000038866 AllianceGenome:MGI:2444114
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
9930114B20Rik
Summary
Predicted to enable nucleic acid binding activity; phosphatidylinositol binding activity; and zinc ion binding activity. Predicted to be located in cytoplasm. Is expressed in metanephros; submandibular gland primordium; and thymus primordium. Orthologous to human ZCCHC2 (zinc finger CCHC-type containing 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 19.4), thymus adult (RPKM 8.8) and 28 other tissues See more
Orthologs
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Genomic context

See Zcchc2 in Genome Data Viewer
Location:
1 E2.1; 1 49.76 cM
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (105916929..105961807)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (105990390..106034077)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 26214 Neighboring gene zinc finger protein of the cerebellum 5 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E795 Neighboring gene STARR-positive B cell enhancer ABC_E8772 Neighboring gene STARR-positive B cell enhancer ABC_E5787 Neighboring gene predicted gene 7160 Neighboring gene STARR-seq mESC enhancer starr_01847 Neighboring gene STARR-positive B cell enhancer ABC_E4340 Neighboring gene STARR-positive B cell enhancer ABC_E2556 Neighboring gene STARR-seq mESC enhancer starr_01848 Neighboring gene predicted gene, 26509 Neighboring gene STARR-seq mESC enhancer starr_01850 Neighboring gene STARR-positive B cell enhancer ABC_E9059 Neighboring gene STARR-positive B cell enhancer ABC_E2005 Neighboring gene predicted gene, 20753

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables molecular_function ND
No biological Data available
more info
 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
enables phosphatidylinositol binding IEA
Inferred from Electronic Annotation
more info
 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
zinc finger CCHC domain-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001122675.1NP_001116147.1  zinc finger CCHC domain-containing protein 2 isoform B

    Status: VALIDATED

    Source sequence(s)
    AK046562, AK173248, BP762779
    Consensus CDS
    CCDS48336.1
    UniProtKB/Swiss-Prot
    Q69ZB8
    Related
    ENSMUSP00000113128.2, ENSMUST00000119166.8
    Conserved Domains (2) summary
    pfam00098
    Location:11211136
    zf-CCHC; Zinc knuckle
    cl02563
    Location:341433
    PX_domain; The Phox Homology domain, a phosphoinositide binding module
  2. NM_001122676.1NP_001116148.1  zinc finger CCHC domain-containing protein 2 isoform A

    See identical proteins and their annotated locations for NP_001116148.1

    Status: VALIDATED

    Source sequence(s)
    AK046562, AK173248, BC055760, BP762779
    Consensus CDS
    CCDS48335.1
    UniProtKB/Swiss-Prot
    Q69ZB8, Q7TNF1, Q8CB08
    Related
    ENSMUSP00000113974.2, ENSMUST00000118196.8
    Conserved Domains (2) summary
    pfam00098
    Location:11211136
    zf-CCHC; Zinc knuckle
    cl02563
    Location:341433
    PX_domain; The Phox Homology domain, a phosphoinositide binding module

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    105916929..105961807
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006529512.5XP_006529575.1  zinc finger CCHC domain-containing protein 2 isoform X1

    Conserved Domains (4) summary
    PHA03247
    Location:813960
    PHA03247; large tegument protein UL36; Provisional
    pfam00098
    Location:11261141
    zf-CCHC; Zinc knuckle
    pfam17823
    Location:657944
    DUF5585; Family of unknown function (DUF5585)
    cl02563
    Location:341433
    PX_domain; The Phox Homology domain, a phosphoinositide binding module
  2. XM_006529516.5XP_006529579.1  zinc finger CCHC domain-containing protein 2 isoform X6

    Conserved Domains (4) summary
    PHA03379
    Location:7391066
    PHA03379; EBNA-3A; Provisional
    pfam00098
    Location:10781093
    zf-CCHC; Zinc knuckle
    pfam17823
    Location:587896
    DUF5585; Family of unknown function (DUF5585)
    cl02563
    Location:341433
    PX_domain; The Phox Homology domain, a phosphoinositide binding module
  3. XM_006529514.5XP_006529577.1  zinc finger CCHC domain-containing protein 2 isoform X3

    Conserved Domains (4) summary
    PHA03247
    Location:785932
    PHA03247; large tegument protein UL36; Provisional
    pfam00098
    Location:10981113
    zf-CCHC; Zinc knuckle
    pfam17823
    Location:629916
    DUF5585; Family of unknown function (DUF5585)
    cl02563
    Location:341433
    PX_domain; The Phox Homology domain, a phosphoinositide binding module
  4. XM_006529515.5XP_006529578.1  zinc finger CCHC domain-containing protein 2 isoform X5

    Conserved Domains (4) summary
    PHA03247
    Location:780927
    PHA03247; large tegument protein UL36; Provisional
    pfam00098
    Location:10931108
    zf-CCHC; Zinc knuckle
    pfam17823
    Location:624911
    DUF5585; Family of unknown function (DUF5585)
    cl02563
    Location:341433
    PX_domain; The Phox Homology domain, a phosphoinositide binding module
  5. XM_030253840.2XP_030109700.1  zinc finger CCHC domain-containing protein 2 isoform X9

    Conserved Domains (4) summary
    PHA03379
    Location:7111038
    PHA03379; EBNA-3A; Provisional
    pfam00098
    Location:10501065
    zf-CCHC; Zinc knuckle
    pfam17823
    Location:559868
    DUF5585; Family of unknown function (DUF5585)
    cl02563
    Location:341433
    PX_domain; The Phox Homology domain, a phosphoinositide binding module
  6. XM_006529513.5XP_006529576.1  zinc finger CCHC domain-containing protein 2 isoform X2

    Conserved Domains (3) summary
    PHA03247
    Location:789936
    PHA03247; large tegument protein UL36; Provisional
    pfam00098
    Location:11021117
    zf-CCHC; Zinc knuckle
    pfam17823
    Location:633920
    DUF5585; Family of unknown function (DUF5585)
  7. XM_030253835.2XP_030109695.1  zinc finger CCHC domain-containing protein 2 isoform X4

    Conserved Domains (3) summary
    PHA03247
    Location:784931
    PHA03247; large tegument protein UL36; Provisional
    pfam00098
    Location:10971112
    zf-CCHC; Zinc knuckle
    pfam17823
    Location:628915
    DUF5585; Family of unknown function (DUF5585)
  8. XM_006529517.5XP_006529580.1  zinc finger CCHC domain-containing protein 2 isoform X7

    Conserved Domains (3) summary
    PHA03247
    Location:761908
    PHA03247; large tegument protein UL36; Provisional
    pfam00098
    Location:10741089
    zf-CCHC; Zinc knuckle
    pfam17823
    Location:605892
    DUF5585; Family of unknown function (DUF5585)
  9. XM_006529518.5XP_006529581.1  zinc finger CCHC domain-containing protein 2 isoform X8

    Conserved Domains (3) summary
    PHA03247
    Location:756903
    PHA03247; large tegument protein UL36; Provisional
    pfam00098
    Location:10691084
    zf-CCHC; Zinc knuckle
    pfam17823
    Location:600887
    DUF5585; Family of unknown function (DUF5585)