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B3gnt7 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 [ Mus musculus (house mouse) ]

Gene ID: 227327, updated on 13-Jul-2024

Summary

Official Symbol
B3gnt7provided by MGI
Official Full Name
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7provided by MGI
Primary source
MGI:MGI:2384394
See related
Ensembl:ENSMUSG00000079445 AllianceGenome:MGI:2384394
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
beta-3GnT7; C330001H22Rik
Summary
Predicted to enable acetylglucosaminyltransferase activity. Predicted to be involved in poly-N-acetyllactosamine biosynthetic process. Predicted to act upstream of or within protein glycosylation. Predicted to be located in Golgi apparatus and membrane. Predicted to be integral component of membrane. Predicted to be active in Golgi membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human B3GNT7 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in colon adult (RPKM 350.5), large intestine adult (RPKM 52.5) and 1 other tissue See more
Orthologs
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Genomic context

See B3gnt7 in Genome Data Viewer
Location:
1 C5; 1 43.94 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (86230943..86235027)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (86303221..86307305)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene armadillo repeat containing 9 Neighboring gene STARR-positive B cell enhancer mm9_chr1:88154834-88155134 Neighboring gene predicted gene, 46098 Neighboring gene predicted gene 16341 Neighboring gene CRISPRi-validated B3gnt7 cis-regulatory element Neighboring gene predicted gene 28626 Neighboring gene predicted gene 5258 Neighboring gene STARR-seq mESC enhancer starr_01572 Neighboring gene small nucleolar RNA, H/ACA box 75 Neighboring gene nucleolin

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables UDP-glycosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables acetylglucosaminyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
enables acetylglucosaminyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables hexosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in keratan sulfate biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in keratan sulfate biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
involved_in poly-N-acetyllactosamine biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein O-linked glycosylation IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within protein glycosylation ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
is_active_in Golgi membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
Names
BGnT-7
beta-1,3-Gn-T7
beta-1,3-N-acetylglucosaminyltransferase 7
beta3Gn-T7
NP_660257.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_145222.2NP_660257.2  UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7

    See identical proteins and their annotated locations for NP_660257.2

    Status: VALIDATED

    Source sequence(s)
    AK131975, AV456413, BB591167, BX521960
    Consensus CDS
    CCDS35645.1
    UniProtKB/Swiss-Prot
    Q3U3L9, Q3V283, Q6PA02, Q8BJS5, Q8K0J2, Q8K437
    Related
    ENSMUSP00000108931.3, ENSMUST00000113306.4
    Conserved Domains (1) summary
    cl21608
    Location:144338
    Galactosyl_T; Galactosyltransferase

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    86230943..86235027
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)