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FHL1 four and a half LIM domains 1 [ Homo sapiens (human) ]

Gene ID: 2273, updated on 19-Sep-2024

Summary

Official Symbol
FHL1provided by HGNC
Official Full Name
four and a half LIM domains 1provided by HGNC
Primary source
HGNC:HGNC:3702
See related
Ensembl:ENSG00000022267 MIM:300163; AllianceGenome:HGNC:3702
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
KYOT; SLIM; FCMSU; FHL-1; FHL1A; FHL1B; FLH1A; SLIM1; XMPMA; RBMX1A; RBMX1B; SLIM-1; SLIMMER
Summary
This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. Expression of these family members occurs in a cell- and tissue-specific mode and these proteins are involved in many cellular processes. Mutations in this gene have been found in patients with Emery-Dreifuss muscular dystrophy. Multiple alternately spliced transcript variants which encode different protein isoforms have been described.[provided by RefSeq, Nov 2009]
Expression
Broad expression in heart (RPKM 286.6), fat (RPKM 281.6) and 18 other tissues See more
Orthologs
NEW
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Try the new Transcript table

Genomic context

See FHL1 in Genome Data Viewer
Location:
Xq26.3
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (136146702..136211359)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (134455091..134519750)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (135228861..135293518)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chrX:135179522-135180721 Neighboring gene E2F transcription factor 6 pseudogene 4 Neighboring gene ReSE screen-validated silencer GRCh37_chrX:135196669-135196868 Neighboring gene small nucleolar RNA U13 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chrX:135225551-135226750 Neighboring gene Sharpr-MPRA regulatory region 1893 Neighboring gene MAP7 domain containing 3 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 21026 Neighboring gene serine/threonine kinase 24 pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC111107

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables molecular_function ND
No biological Data available
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables transmembrane transporter binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables transmembrane transporter binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
 
located_in focal adhesion HDA PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
four and a half LIM domains protein 1
Names
LIM protein SLIMMER
four-and-a-half Lin11, Isl-1 and Mec-3 domains 1
skeletal muscle LIM-protein 1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_015895.1 RefSeqGene

    Range
    5134..68955
    Download
    GenBank, FASTA, Sequence Viewer (Graphics), LRG_739

mRNA and Protein(s)

  1. NM_001159699.2NP_001153171.1  four and a half LIM domains protein 1 isoform 5

    See identical proteins and their annotated locations for NP_001153171.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7) differs in the 5' UTR, 3' UTR, and 3' coding region and initiates translation at an alternate start codon, compared to variant 1. The encoded protein (isoform 5) has distinct N- and C-termini and is shorter than isoform 1.
    Source sequence(s)
    BC088369, BM995585, DC373386
    Consensus CDS
    CCDS55506.1
    UniProtKB/TrEMBL
    Q53FI7
    Related
    ENSP00000359717.1, ENST00000370683.6
    Conserved Domains (5) summary
    cd09344
    Location:56109
    LIM1_FHL1; The first LIM domain of Four and a half LIM domains protein 1
    cd09348
    Location:233296
    LIM4_FHL1; The fourth LIM domain of Four and a half LIM domains protein 1 (FHL1)
    cd09424
    Location:117174
    LIM2_FHL1; The second LIM domain of Four and a half LIM domains protein 1 (FHL1)
    cd09429
    Location:178230
    LIM3_FHL1; The third LIM domain of Four and a half LIM domains protein 1 (FHL1)
    cl02475
    Location:2149
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
  2. NM_001159700.2NP_001153172.1  four and a half LIM domains protein 1 isoform 2

    See identical proteins and their annotated locations for NP_001153172.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR, 3' UTR, and 3' coding region compared to variant 1. The encoded protein (isoform 2) has a distinct C-terminus and is shorter than isoform 1. Variants 2, 3, 4 and 9 encode the same protein (isoform 2).
    Source sequence(s)
    AK304680, AL078638, BC088369, BM995585, DC363191
    Consensus CDS
    CCDS14655.1
    UniProtKB/TrEMBL
    Q53FI7
    Related
    ENSP00000485897.1, ENST00000630084.2
    Conserved Domains (5) summary
    cd09344
    Location:4093
    LIM1_FHL1; The first LIM domain of Four and a half LIM domains protein 1
    cd09348
    Location:217280
    LIM4_FHL1; The fourth LIM domain of Four and a half LIM domains protein 1 (FHL1)
    cd09424
    Location:101158
    LIM2_FHL1; The second LIM domain of Four and a half LIM domains protein 1 (FHL1)
    cd09429
    Location:162214
    LIM3_FHL1; The third LIM domain of Four and a half LIM domains protein 1 (FHL1)
    cl02475
    Location:533
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
  3. NM_001159701.2NP_001153173.1  four and a half LIM domains protein 1 isoform 3 precursor

    See identical proteins and their annotated locations for NP_001153173.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR, 3' UTR, and coding region and initiates translation at an alternate start codon, compared to variant 1. The encoded protein (isoform 3) is shorter and has distinct N- and C-termini, compared to isoform 1.
    Source sequence(s)
    AK301642, BC010998, BM995585
    Consensus CDS
    CCDS55505.1
    UniProtKB/TrEMBL
    Q53FI7
    Related
    ENSP00000437673.1, ENST00000539015.5
    Conserved Domains (5) summary
    cd09344
    Location:69122
    LIM1_FHL1; The first LIM domain of Four and a half LIM domains protein 1
    cd09348
    Location:246309
    LIM4_FHL1; The fourth LIM domain of Four and a half LIM domains protein 1 (FHL1)
    cd09424
    Location:130187
    LIM2_FHL1; The second LIM domain of Four and a half LIM domains protein 1 (FHL1)
    cd09429
    Location:191243
    LIM3_FHL1; The third LIM domain of Four and a half LIM domains protein 1 (FHL1)
    cl02475
    Location:3462
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
  4. NM_001159702.3NP_001153174.1  four and a half LIM domains protein 1 isoform 1

    See identical proteins and their annotated locations for NP_001153174.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) encodes the longest protein (isoform 1).
    Source sequence(s)
    AF063002, AF098518, BC010998, BM995585
    Consensus CDS
    CCDS55507.1
    UniProtKB/Swiss-Prot
    B7Z5T4, B7Z793, O95212, Q13230, Q13642, Q13645, Q5JXI7, Q5M7Y6, Q6IB30, Q9NZ40, Q9UKZ8, Q9Y630
    Related
    ENSP00000377710.2, ENST00000394155.8
    Conserved Domains (4) summary
    cd09344
    Location:4093
    LIM1_FHL1; The first LIM domain of Four and a half LIM domains protein 1
    cd09424
    Location:101158
    LIM2_FHL1; The second LIM domain of Four and a half LIM domains protein 1 (FHL1)
    cd09429
    Location:162214
    LIM3_FHL1; The third LIM domain of Four and a half LIM domains protein 1 (FHL1)
    cl02475
    Location:533
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
  5. NM_001159703.2NP_001153175.1  four and a half LIM domains protein 1 isoform 4

    See identical proteins and their annotated locations for NP_001153175.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR and coding region, compared to variant 1. The encoded protein (isoform 4) is shorter than isoform 1.
    Source sequence(s)
    AF220153, AK301642, AL078638, BC010998, BE965488, BM995585, DA497183
    Consensus CDS
    CCDS76036.1
    UniProtKB/TrEMBL
    A0A0D9SFZ9
    Related
    ENSP00000477609.1, ENST00000618438.4
    Conserved Domains (3) summary
    cd09344
    Location:4093
    LIM1_FHL1; The first LIM domain of Four and a half LIM domains protein 1
    cd09424
    Location:101158
    LIM2_FHL1; The second LIM domain of Four and a half LIM domains protein 1 (FHL1)
    cl02475
    Location:533
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
  6. NM_001159704.1NP_001153176.1  four and a half LIM domains protein 1 isoform 2

    See identical proteins and their annotated locations for NP_001153176.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR, 3' UTR, and 3' coding region compared to variant 1. The encoded protein (isoform 2) has a distinct C-terminus and is shorter than isoform 1. Variants 2, 3, 4 and 9 encode the same protein (isoform 2).
    Source sequence(s)
    AK122708, AL078638, BM995585
    Consensus CDS
    CCDS14655.1
    UniProtKB/TrEMBL
    Q53FI7
    Related
    ENSP00000443333.1, ENST00000543669.5
    Conserved Domains (5) summary
    cd09344
    Location:4093
    LIM1_FHL1; The first LIM domain of Four and a half LIM domains protein 1
    cd09348
    Location:217280
    LIM4_FHL1; The fourth LIM domain of Four and a half LIM domains protein 1 (FHL1)
    cd09424
    Location:101158
    LIM2_FHL1; The second LIM domain of Four and a half LIM domains protein 1 (FHL1)
    cd09429
    Location:162214
    LIM3_FHL1; The third LIM domain of Four and a half LIM domains protein 1 (FHL1)
    cl02475
    Location:533
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
  7. NM_001167819.1NP_001161291.1  four and a half LIM domains protein 1 isoform 2

    See identical proteins and their annotated locations for NP_001161291.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (9) uses a different segment for its 5' UTR and lacks an alternate exon in the 3' coding region, compared to variant 1. The encoded protein (isoform 2) has a distinct C-terminus and is shorter than isoform 1. Variants 2, 3, 4 and 9 encode the same protein (isoform 2).
    Source sequence(s)
    BC010998, BM995585, DA917361, DA982372
    Consensus CDS
    CCDS14655.1
    UniProtKB/TrEMBL
    Q53FI7
    Related
    ENSP00000377709.2, ENST00000394153.6
    Conserved Domains (5) summary
    cd09344
    Location:4093
    LIM1_FHL1; The first LIM domain of Four and a half LIM domains protein 1
    cd09348
    Location:217280
    LIM4_FHL1; The fourth LIM domain of Four and a half LIM domains protein 1 (FHL1)
    cd09424
    Location:101158
    LIM2_FHL1; The second LIM domain of Four and a half LIM domains protein 1 (FHL1)
    cd09429
    Location:162214
    LIM3_FHL1; The third LIM domain of Four and a half LIM domains protein 1 (FHL1)
    cl02475
    Location:533
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
  8. NM_001330659.2NP_001317588.1  four and a half LIM domains protein 1 isoform 6

    Status: REVIEWED

    Description
    Transcript Variant: This variant (10) uses an alternate 5'-terminal exon, lacks two in-frame exons in the 3' coding region, and uses an alternate start codon, compared to variant 1. The encoded isoform (6) is shorter and has a distinct N-terminus, compared to isoform 1.
    Source sequence(s)
    AL078638
    Consensus CDS
    CCDS83493.1
    UniProtKB/TrEMBL
    A0A0D9SFZ9, Q5JXI2
    Related
    ENSP00000359710.3, ENST00000370676.7
    Conserved Domains (3) summary
    cd09344
    Location:56109
    LIM1_FHL1; The first LIM domain of Four and a half LIM domains protein 1
    cd09424
    Location:117174
    LIM2_FHL1; The second LIM domain of Four and a half LIM domains protein 1 (FHL1)
    cl02475
    Location:2149
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
  9. NM_001369326.1NP_001356255.1  four and a half LIM domains protein 1 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AL078638
    Consensus CDS
    CCDS55507.1
    UniProtKB/Swiss-Prot
    B7Z5T4, B7Z793, O95212, Q13230, Q13642, Q13645, Q5JXI7, Q5M7Y6, Q6IB30, Q9NZ40, Q9UKZ8, Q9Y630
    Related
    ENSP00000498684.1, ENST00000651089.1
    Conserved Domains (4) summary
    cd09344
    Location:4093
    LIM1_FHL1; The first LIM domain of Four and a half LIM domains protein 1
    cd09424
    Location:101158
    LIM2_FHL1; The second LIM domain of Four and a half LIM domains protein 1 (FHL1)
    cd09429
    Location:162214
    LIM3_FHL1; The third LIM domain of Four and a half LIM domains protein 1 (FHL1)
    cl02475
    Location:533
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
  10. NM_001369327.2NP_001356256.1  four and a half LIM domains protein 1 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AL078638
    Consensus CDS
    CCDS55507.1
    UniProtKB/Swiss-Prot
    B7Z5T4, B7Z793, O95212, Q13230, Q13642, Q13645, Q5JXI7, Q5M7Y6, Q6IB30, Q9NZ40, Q9UKZ8, Q9Y630
    Conserved Domains (4) summary
    cd09344
    Location:4093
    LIM1_FHL1; The first LIM domain of Four and a half LIM domains protein 1
    cd09424
    Location:101158
    LIM2_FHL1; The second LIM domain of Four and a half LIM domains protein 1 (FHL1)
    cd09429
    Location:162214
    LIM3_FHL1; The third LIM domain of Four and a half LIM domains protein 1 (FHL1)
    cl02475
    Location:533
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
  11. NM_001369328.1NP_001356257.1  four and a half LIM domains protein 1 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AL078638
    Consensus CDS
    CCDS55507.1
    UniProtKB/Swiss-Prot
    B7Z5T4, B7Z793, O95212, Q13230, Q13642, Q13645, Q5JXI7, Q5M7Y6, Q6IB30, Q9NZ40, Q9UKZ8, Q9Y630
    Conserved Domains (4) summary
    cd09344
    Location:4093
    LIM1_FHL1; The first LIM domain of Four and a half LIM domains protein 1
    cd09424
    Location:101158
    LIM2_FHL1; The second LIM domain of Four and a half LIM domains protein 1 (FHL1)
    cd09429
    Location:162214
    LIM3_FHL1; The third LIM domain of Four and a half LIM domains protein 1 (FHL1)
    cl02475
    Location:533
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
  12. NM_001369329.1NP_001356258.1  four and a half LIM domains protein 1 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AL078638
    Consensus CDS
    CCDS14655.1
    UniProtKB/TrEMBL
    Q53FI7
    Conserved Domains (5) summary
    cd09344
    Location:4093
    LIM1_FHL1; The first LIM domain of Four and a half LIM domains protein 1
    cd09348
    Location:217280
    LIM4_FHL1; The fourth LIM domain of Four and a half LIM domains protein 1 (FHL1)
    cd09424
    Location:101158
    LIM2_FHL1; The second LIM domain of Four and a half LIM domains protein 1 (FHL1)
    cd09429
    Location:162214
    LIM3_FHL1; The third LIM domain of Four and a half LIM domains protein 1 (FHL1)
    cl02475
    Location:533
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
  13. NM_001369330.1NP_001356259.1  four and a half LIM domains protein 1 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AL078638
    Consensus CDS
    CCDS14655.1
    UniProtKB/TrEMBL
    Q53FI7
    Related
    ENSP00000444815.1, ENST00000535737.5
    Conserved Domains (5) summary
    cd09344
    Location:4093
    LIM1_FHL1; The first LIM domain of Four and a half LIM domains protein 1
    cd09348
    Location:217280
    LIM4_FHL1; The fourth LIM domain of Four and a half LIM domains protein 1 (FHL1)
    cd09424
    Location:101158
    LIM2_FHL1; The second LIM domain of Four and a half LIM domains protein 1 (FHL1)
    cd09429
    Location:162214
    LIM3_FHL1; The third LIM domain of Four and a half LIM domains protein 1 (FHL1)
    cl02475
    Location:533
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
  14. NM_001369331.1NP_001356260.1  four and a half LIM domains protein 1 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AL078638
    Consensus CDS
    CCDS14655.1
    UniProtKB/TrEMBL
    Q53FI7
    Related
    ENSP00000359708.1, ENST00000370674.3
    Conserved Domains (5) summary
    cd09344
    Location:4093
    LIM1_FHL1; The first LIM domain of Four and a half LIM domains protein 1
    cd09348
    Location:217280
    LIM4_FHL1; The fourth LIM domain of Four and a half LIM domains protein 1 (FHL1)
    cd09424
    Location:101158
    LIM2_FHL1; The second LIM domain of Four and a half LIM domains protein 1 (FHL1)
    cd09429
    Location:162214
    LIM3_FHL1; The third LIM domain of Four and a half LIM domains protein 1 (FHL1)
    cl02475
    Location:533
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
  15. NM_001449.5NP_001440.2  four and a half LIM domains protein 1 isoform 2

    See identical proteins and their annotated locations for NP_001440.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, 3' UTR, and 3' coding region compared to variant 1. The encoded protein (isoform 2) has a distinct C-terminus and is shorter than isoform 1. Variants 2, 3, 4 and 9 encode the same protein (isoform 2).
    Source sequence(s)
    BC010998, BM995585
    Consensus CDS
    CCDS14655.1
    UniProtKB/TrEMBL
    Q53FI7
    Related
    ENSP00000499016.1, ENST00000651929.2
    Conserved Domains (5) summary
    cd09344
    Location:4093
    LIM1_FHL1; The first LIM domain of Four and a half LIM domains protein 1
    cd09348
    Location:217280
    LIM4_FHL1; The fourth LIM domain of Four and a half LIM domains protein 1 (FHL1)
    cd09424
    Location:101158
    LIM2_FHL1; The second LIM domain of Four and a half LIM domains protein 1 (FHL1)
    cd09429
    Location:162214
    LIM3_FHL1; The third LIM domain of Four and a half LIM domains protein 1 (FHL1)
    cl02475
    Location:533
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

RNA

  1. NR_027621.2 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (8) includes an additional exon at the 5' end, compared to variant 1. This variant is represented as non-coding because it contains an upstream ORF that is predicted to interfere with translation of the downstream expected ORF as used in variant 1.
    Source sequence(s)
    AK289411, AL078638, BC010998, BM995585

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

    Range
    136146702..136211359
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047441926.1XP_047297882.1  four and a half LIM domains protein 1 isoform X2

    UniProtKB/Swiss-Prot
    B7Z5T4, B7Z793, O95212, Q13230, Q13642, Q13645, Q5JXI7, Q5M7Y6, Q6IB30, Q9NZ40, Q9UKZ8, Q9Y630
  2. XM_047441927.1XP_047297883.1  four and a half LIM domains protein 1 isoform X3

    UniProtKB/TrEMBL
    Q53FI7
  3. XM_024452354.2XP_024308122.1  four and a half LIM domains protein 1 isoform X2

    UniProtKB/Swiss-Prot
    B7Z5T4, B7Z793, O95212, Q13230, Q13642, Q13645, Q5JXI7, Q5M7Y6, Q6IB30, Q9NZ40, Q9UKZ8, Q9Y630
    Conserved Domains (4) summary
    cd09344
    Location:4093
    LIM1_FHL1; The first LIM domain of Four and a half LIM domains protein 1
    cd09424
    Location:101158
    LIM2_FHL1; The second LIM domain of Four and a half LIM domains protein 1 (FHL1)
    cd09429
    Location:162214
    LIM3_FHL1; The third LIM domain of Four and a half LIM domains protein 1 (FHL1)
    cl02475
    Location:533
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
  4. XM_047441925.1XP_047297881.1  four and a half LIM domains protein 1 isoform X2

    UniProtKB/Swiss-Prot
    B7Z5T4, B7Z793, O95212, Q13230, Q13642, Q13645, Q5JXI7, Q5M7Y6, Q6IB30, Q9NZ40, Q9UKZ8, Q9Y630
  5. XM_006724743.3XP_006724806.1  four and a half LIM domains protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006724806.1

    Conserved Domains (4) summary
    cd09344
    Location:56109
    LIM1_FHL1; The first LIM domain of Four and a half LIM domains protein 1
    cd09424
    Location:117174
    LIM2_FHL1; The second LIM domain of Four and a half LIM domains protein 1 (FHL1)
    cd09429
    Location:178230
    LIM3_FHL1; The third LIM domain of Four and a half LIM domains protein 1 (FHL1)
    cl02475
    Location:2149
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
  6. XM_006724746.4XP_006724809.1  four and a half LIM domains protein 1 isoform X2

    See identical proteins and their annotated locations for XP_006724809.1

    UniProtKB/Swiss-Prot
    B7Z5T4, B7Z793, O95212, Q13230, Q13642, Q13645, Q5JXI7, Q5M7Y6, Q6IB30, Q9NZ40, Q9UKZ8, Q9Y630
    Conserved Domains (4) summary
    cd09344
    Location:4093
    LIM1_FHL1; The first LIM domain of Four and a half LIM domains protein 1
    cd09424
    Location:101158
    LIM2_FHL1; The second LIM domain of Four and a half LIM domains protein 1 (FHL1)
    cd09429
    Location:162214
    LIM3_FHL1; The third LIM domain of Four and a half LIM domains protein 1 (FHL1)
    cl02475
    Location:533
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060947.1 Alternate T2T-CHM13v2.0

    Range
    134455091..134519750
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054326701.1XP_054182676.1  four and a half LIM domains protein 1 isoform X2

    UniProtKB/Swiss-Prot
    B7Z5T4, B7Z793, O95212, Q13230, Q13642, Q13645, Q5JXI7, Q5M7Y6, Q6IB30, Q9NZ40, Q9UKZ8, Q9Y630
  2. XM_054326702.1XP_054182677.1  four and a half LIM domains protein 1 isoform X3

    UniProtKB/TrEMBL
    Q53FI7
  3. XM_054326700.1XP_054182675.1  four and a half LIM domains protein 1 isoform X2

    UniProtKB/Swiss-Prot
    B7Z5T4, B7Z793, O95212, Q13230, Q13642, Q13645, Q5JXI7, Q5M7Y6, Q6IB30, Q9NZ40, Q9UKZ8, Q9Y630
  4. XM_054326699.1XP_054182674.1  four and a half LIM domains protein 1 isoform X2

    UniProtKB/Swiss-Prot
    B7Z5T4, B7Z793, O95212, Q13230, Q13642, Q13645, Q5JXI7, Q5M7Y6, Q6IB30, Q9NZ40, Q9UKZ8, Q9Y630
  5. XM_054326697.1XP_054182672.1  four and a half LIM domains protein 1 isoform X1

  6. XM_054326698.1XP_054182673.1  four and a half LIM domains protein 1 isoform X2

    UniProtKB/Swiss-Prot
    B7Z5T4, B7Z793, O95212, Q13230, Q13642, Q13645, Q5JXI7, Q5M7Y6, Q6IB30, Q9NZ40, Q9UKZ8, Q9Y630