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Ino80d INO80 complex subunit D [ Mus musculus (house mouse) ]

Gene ID: 227195, updated on 26-Sep-2022

Summary

Official Symbol
Ino80dprovided by MGI
Official Full Name
INO80 complex subunit Dprovided by MGI
Primary source
MGI:MGI:3027003
See related
Ensembl:ENSMUSG00000040865 AllianceGenome:MGI:3027003
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
7330405I11; A430093A21Rik
Summary
Predicted to act upstream of or within DNA recombination and DNA repair. Predicted to be active in nucleus. Is expressed in several structures, including endocrine gland; gallbladder; genitourinary system; nervous system; and skeletal muscle tissue. Orthologous to human INO80D (INO80 complex subunit D). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in thymus adult (RPKM 7.5), lung adult (RPKM 4.6) and 28 other tissues See more
Orthologs
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Genomic context

See Ino80d in Genome Data Viewer
Location:
1; 1 C2
Exon count:
16
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (63086960..63153426, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (63047801..63114267, complement)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 44468 Neighboring gene predicted gene, 24942 Neighboring gene ribosomal protein S27, pseudogene 1 Neighboring gene INO80 complex subunit D, opposite strand Neighboring gene NADH:ubiquinone oxidoreductase core subunit S1 Neighboring gene predicted gene, 26457 Neighboring gene eukaryotic translation elongation factor 1 beta 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 
  • Endonuclease-mediated (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Component Evidence Code Pubs
part_of Ino80 complex ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081436.3NP_001074905.1  INO80 complex subunit D isoform 2

    See identical proteins and their annotated locations for NP_001074905.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) has an alternate splice site, which results in a downstream AUG start codon, as compared to variant 1. The resulting isoform (2) has a shorter N-terminus, as compared to isoform 1.
    Source sequence(s)
    AL645685, AL645950
    Consensus CDS
    CCDS35594.1
    UniProtKB/Swiss-Prot
    Q66JY2
    UniProtKB/TrEMBL
    B1AT32
    Related
    ENSMUSP00000115332.3, ENSMUST00000153992.3
    Conserved Domains (2) summary
    PRK14971
    Location:65195
    PRK14971; DNA polymerase III subunit gamma/tau
    pfam13891
    Location:337401
    zf-C3Hc3H; Potential DNA-binding domain
  2. NM_001114609.2NP_001108081.1  INO80 complex subunit D isoform 1

    See identical proteins and their annotated locations for NP_001108081.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) is the longer transcript and encodes the longer isoform.
    Source sequence(s)
    AL645685, AL645950
    Consensus CDS
    CCDS48277.1
    UniProtKB/Swiss-Prot
    Q66JY2, Q8BQK5
    UniProtKB/TrEMBL
    E9Q9Q0
    Related
    ENSMUSP00000119118.3, ENSMUST00000137511.9
    Conserved Domains (2) summary
    PRK14971
    Location:170300
    PRK14971; DNA polymerase III subunit gamma/tau
    pfam13891
    Location:1879
    zf-C3Hc3H; Potential DNA-binding domain
  3. NM_001406701.1NP_001393630.1  INO80 complex subunit D isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL645685, AL645950
    UniProtKB/Swiss-Prot
    Q8BQK5
  4. NM_001406702.1NP_001393631.1  INO80 complex subunit D isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL645685, AL645950
    UniProtKB/Swiss-Prot
    Q8BQK5
  5. NM_001406703.1NP_001393632.1  INO80 complex subunit D isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL645685, AL645950
    UniProtKB/Swiss-Prot
    Q8BQK5
  6. NM_001406704.1NP_001393633.1  INO80 complex subunit D isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL645685, AL645950
    UniProtKB/Swiss-Prot
    Q8BQK5
  7. NM_001406705.1NP_001393634.1  INO80 complex subunit D isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL645685, AL645950
    UniProtKB/Swiss-Prot
    Q8BQK5
  8. NM_001406706.1NP_001393635.1  INO80 complex subunit D isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL645685, AL645950
    UniProtKB/Swiss-Prot
    Q8BQK5
  9. NM_001406707.1NP_001393636.1  INO80 complex subunit D isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL645685, AL645950
    UniProtKB/Swiss-Prot
    Q8BQK5
  10. NM_001406708.1NP_001393637.1  INO80 complex subunit D isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL645685, AL645950
    UniProtKB/Swiss-Prot
    Q8BQK5
  11. NM_001406709.1NP_001393638.1  INO80 complex subunit D isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL645685, AL645950
    UniProtKB/Swiss-Prot
    Q8BQK5
  12. NM_001406710.1NP_001393639.1  INO80 complex subunit D isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL645685, AL645950
    UniProtKB/TrEMBL
    B1AT32
  13. NM_001406711.1NP_001393640.1  INO80 complex subunit D isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL645685, AL645950
    UniProtKB/TrEMBL
    B1AT32
  14. NM_001406712.1NP_001393641.1  INO80 complex subunit D isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL645685, AL645950
    UniProtKB/TrEMBL
    B1AT32
  15. NM_001406713.1NP_001393642.1  INO80 complex subunit D isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL645685, AL645950
    UniProtKB/TrEMBL
    B1AT32
  16. NM_001406714.1NP_001393643.1  INO80 complex subunit D isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL645685, AL645950
    UniProtKB/TrEMBL
    B1AT32

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    63086960..63153426 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030253691.2XP_030109551.1  INO80 complex subunit D isoform X2

    Conserved Domains (2) summary
    PRK14971
    Location:65195
    PRK14971; DNA polymerase III subunit gamma/tau
    pfam13891
    Location:337401
    zf-C3Hc3H; Potential DNA-binding domain
  2. XM_006495946.4XP_006496009.1  INO80 complex subunit D isoform X1

    UniProtKB/TrEMBL
    E9Q9Q0
    Conserved Domains (2) summary
    PRK14971
    Location:170300
    PRK14971; DNA polymerase III subunit gamma/tau
    pfam13891
    Location:1879
    zf-C3Hc3H; Potential DNA-binding domain
  3. XM_006495947.4XP_006496010.1  INO80 complex subunit D isoform X1

    UniProtKB/TrEMBL
    E9Q9Q0
    Conserved Domains (2) summary
    PRK14971
    Location:170300
    PRK14971; DNA polymerase III subunit gamma/tau
    pfam13891
    Location:1879
    zf-C3Hc3H; Potential DNA-binding domain
  4. XM_006495948.4XP_006496011.1  INO80 complex subunit D isoform X1

    UniProtKB/TrEMBL
    E9Q9Q0
    Conserved Domains (2) summary
    PRK14971
    Location:170300
    PRK14971; DNA polymerase III subunit gamma/tau
    pfam13891
    Location:1879
    zf-C3Hc3H; Potential DNA-binding domain