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Zfp40 zinc finger protein 40 [ Mus musculus (house mouse) ]

Gene ID: 22700, updated on 8-Dec-2022

Summary

Official Symbol
Zfp40provided by MGI
Official Full Name
zinc finger protein 40provided by MGI
Primary source
MGI:MGI:99185
See related
Ensembl:ENSMUSG00000002617 AllianceGenome:MGI:99185
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Zfp-40; CTfin12; NTfin12
Summary
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; embryo mesoderm; genitourinary system; peripheral nervous system ganglion; and primitive streak. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in CNS E18 (RPKM 3.0), CNS E14 (RPKM 1.9) and 16 other tissues See more
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Genomic context

See Zfp40 in Genome Data Viewer
Location:
17 A3.3; 17 11.56 cM
Exon count:
6
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (23392843..23412264, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (23173869..23193284, complement)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene vomeronasal 2, receptor, pseudogene 132 Neighboring gene cytochrome b-c1 complex subunit 7 pseudogene Neighboring gene vomeronasal 2, receptor, pseudogene 133 Neighboring gene vomeronasal 2, receptor 114

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001357697.1NP_001344626.1  zinc finger protein 40 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC151285, BC065097, CT030648
    Consensus CDS
    CCDS37473.1
    UniProtKB/TrEMBL
    B1B1D3
    Conserved Domains (4) summary
    COG5048
    Location:279677
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:644664
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:4282
    KRAB; KRAB box
    pfam13465
    Location:684709
    zf-H2C2_2; Zinc-finger double domain
  2. NM_001414257.1NP_001401186.1  zinc finger protein 40 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC151285, CT030648
  3. NM_001414258.1NP_001401187.1  zinc finger protein 40 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC151285, CT030648
  4. NM_001414259.1NP_001401188.1  zinc finger protein 40 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC151285, CT030648
  5. NM_001414260.1NP_001401189.1  zinc finger protein 40 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC151285, CT030648
  6. NM_001414261.1NP_001401190.1  zinc finger protein 40 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC151285, CT030648
  7. NM_009555.3NP_033581.2  zinc finger protein 40 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC151285, CT030648
    Consensus CDS
    CCDS37473.1
    UniProtKB/TrEMBL
    B1B1D3
    Related
    ENSMUSP00000039794.8, ENSMUST00000037057.14
    Conserved Domains (4) summary
    COG5048
    Location:279677
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:644664
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:4282
    KRAB; KRAB box
    pfam13465
    Location:684709
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    23392843..23412264 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030249752.2XP_030105612.1  zinc finger protein 40 isoform X1

    Conserved Domains (4) summary
    COG5048
    Location:278676
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:643663
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:4181
    KRAB; KRAB box
    pfam13465
    Location:683708
    zf-H2C2_2; Zinc-finger double domain
  2. XM_017317456.3XP_017172945.1  zinc finger protein 40 isoform X1

    Conserved Domains (4) summary
    COG5048
    Location:278676
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:643663
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:4181
    KRAB; KRAB box
    pfam13465
    Location:683708
    zf-H2C2_2; Zinc-finger double domain
  3. XM_030249753.2XP_030105613.1  zinc finger protein 40 isoform X2

    Conserved Domains (4) summary
    COG5048
    Location:270668
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:635655
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:3373
    KRAB; KRAB box
    pfam13465
    Location:675700
    zf-H2C2_2; Zinc-finger double domain