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Actr1b ARP1 actin-related protein 1B, centractin beta [ Mus musculus (house mouse) ]

Gene ID: 226977, updated on 11-Apr-2024

Summary

Official Symbol
Actr1bprovided by MGI
Official Full Name
ARP1 actin-related protein 1B, centractin betaprovided by MGI
Primary source
MGI:MGI:1917446
See related
Ensembl:ENSMUSG00000037351 AllianceGenome:MGI:1917446
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Arp1b; 2310066K23Rik
Summary
Predicted to enable ATP binding activity. Predicted to be located in centrosome and cytoplasm. Is expressed in olfactory epithelium and vomeronasal organ. Orthologous to human ACTR1B (actin related protein 1B). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in cortex adult (RPKM 55.7), cerebellum adult (RPKM 47.4) and 28 other tissues See more
Orthologs
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Genomic context

Location:
1 B; 1 15.38 cM
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (36737195..36749051, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (36698114..36710017, complement)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 178, member B Neighboring gene STARR-seq mESC enhancer starr_00646 Neighboring gene RIKEN cDNA 4933424G06 gene Neighboring gene STARR-positive B cell enhancer ABC_E1539 Neighboring gene cytochrome c oxidase subunit 5B Neighboring gene predicted gene, 33533 Neighboring gene predicted gene, 18828 Neighboring gene zeta-chain (TCR) associated protein kinase

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC36526

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in centrosome ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
part_of dynactin complex IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in microtubule cytoskeleton ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
beta-centractin
Names
ARP1 actin-related protein 1 homolog B, centractin beta
actin-related protein 1B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001418135.1NP_001405064.1  beta-centractin isoform a

    Status: VALIDATED

    Source sequence(s)
    AC084389
  2. NM_001418136.1NP_001405065.1  beta-centractin isoform c

    Status: VALIDATED

    Source sequence(s)
    AC084389
  3. NM_001418137.1NP_001405066.1  beta-centractin isoform d

    Status: VALIDATED

    Source sequence(s)
    AC084389
  4. NM_001418138.1NP_001405067.1  beta-centractin isoform e

    Status: VALIDATED

    Source sequence(s)
    AC084389
  5. NM_001418139.1NP_001405068.1  beta-centractin isoform e

    Status: VALIDATED

    Source sequence(s)
    AC084389
  6. NM_001418140.1NP_001405069.1  beta-centractin isoform e

    Status: VALIDATED

    Source sequence(s)
    AC084389
  7. NM_001418141.1NP_001405070.1  beta-centractin isoform e

    Status: VALIDATED

    Source sequence(s)
    AC084389
  8. NM_001418142.1NP_001405071.1  beta-centractin isoform f

    Status: VALIDATED

    Source sequence(s)
    AC084389
  9. NM_001418143.1NP_001405072.1  beta-centractin isoform g

    Status: VALIDATED

    Source sequence(s)
    AC084389
  10. NM_001418144.1NP_001405073.1  beta-centractin isoform h

    Status: VALIDATED

    Source sequence(s)
    AC084389
  11. NM_146107.3NP_666219.1  beta-centractin isoform b

    See identical proteins and their annotated locations for NP_666219.1

    Status: VALIDATED

    Source sequence(s)
    AC084389
    Consensus CDS
    CCDS14887.1
    UniProtKB/Swiss-Prot
    Q8R5C5
    Related
    ENSMUSP00000047326.4, ENSMUST00000043951.10
    Conserved Domains (1) summary
    cl17037
    Location:5376
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    36737195..36749051 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036164312.1XP_036020205.1  beta-centractin isoform X2

    Conserved Domains (1) summary
    cl17037
    Location:1302
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily