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Ahctf1 AT hook containing transcription factor 1 [ Mus musculus (house mouse) ]

Gene ID: 226747, updated on 5-Mar-2024

Summary

Official Symbol
Ahctf1provided by MGI
Official Full Name
AT hook containing transcription factor 1provided by MGI
Primary source
MGI:MGI:1915033
See related
Ensembl:ENSMUSG00000026491 AllianceGenome:MGI:1915033
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Elys; 6230412P20Rik
Summary
Predicted to enable DNA binding activity. Predicted to be involved in nuclear pore complex assembly and regulation of cytokinesis. Predicted to act upstream of or within cell division; mRNA transport; and protein transport. Located in cytoplasm and nuclear matrix. Is expressed in several structures, including cardiovascular system; central nervous system; early conceptus; genitourinary system; and hemolymphoid system. Orthologous to human AHCTF1 (AT-hook containing transcription factor 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 11.3), placenta adult (RPKM 10.3) and 25 other tissues See more
Orthologs
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Genomic context

See Ahctf1 in Genome Data Viewer
Location:
1 H4; 1 83.62 cM
Exon count:
36
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (179572469..179631580, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (179744904..179804015, complement)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E2590 Neighboring gene STARR-positive B cell enhancer ABC_E4399 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:181508880-181509063 Neighboring gene consortin, connexin sorting protein Neighboring gene STARR-seq mESC enhancer starr_03181 Neighboring gene STARR-seq mESC enhancer starr_03183 Neighboring gene saccharopine dehydrogenase (putative) Neighboring gene kinesin family member 28 Neighboring gene STARR-positive B cell enhancer ABC_E3340 Neighboring gene STARR-positive B cell enhancer ABC_E5865 Neighboring gene STARR-seq mESC enhancer starr_03185 Neighboring gene predicted gene, 31668 Neighboring gene STARR-seq mESC enhancer starr_03186 Neighboring gene CDC42 binding protein kinase alpha Neighboring gene STARR-seq mESC enhancer starr_03187 Neighboring gene predicted gene, 50608

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1)  1 citation
  • Endonuclease-mediated (5) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within cell cycle IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within cell division IEA
Inferred from Electronic Annotation
more info
 
involved_in hemopoiesis TAS
Traceable Author Statement
more info
PubMed 
acts_upstream_of_or_within mRNA transport IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
involved_in nuclear pore complex assembly ISO
Inferred from Sequence Orthology
more info
 
involved_in nucleocytoplasmic transport NAS
Non-traceable Author Statement
more info
PubMed 
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of cytokinesis ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
part_of chromatin ISO
Inferred from Sequence Orthology
more info
 
located_in chromosome IEA
Inferred from Electronic Annotation
more info
 
located_in chromosome, centromeric region IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
colocalizes_with kinetochore ISO
Inferred from Sequence Orthology
more info
 
located_in nuclear body ISO
Inferred from Sequence Orthology
more info
 
located_in nuclear envelope ISO
Inferred from Sequence Orthology
more info
 
located_in nuclear matrix IDA
Inferred from Direct Assay
more info
PubMed 
located_in nuclear membrane ISO
Inferred from Sequence Orthology
more info
 
part_of nuclear pore ISO
Inferred from Sequence Orthology
more info
 
part_of nuclear pore NAS
Non-traceable Author Statement
more info
PubMed 
part_of nuclear pore outer ring ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
protein ELYS
Names
embryonic large molecule derived from yolk sac
putative AT-hook-containing transcription factor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_026375.2NP_080651.2  protein ELYS

    See identical proteins and their annotated locations for NP_080651.2

    Status: VALIDATED

    Source sequence(s)
    AC113977, AC122411
    Consensus CDS
    CCDS15564.1
    UniProtKB/Swiss-Prot
    B2RRC8, Q8BVJ5, Q8CJF7, Q8VD55
    Related
    ENSMUSP00000027768.8, ENSMUST00000027768.14
    Conserved Domains (2) summary
    pfam13934
    Location:722947
    ELYS; Nuclear pore complex assembly
    pfam16687
    Location:2489
    ELYS-bb; beta-propeller of ELYS nucleoporin

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    179572469..179631580 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)