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Trim26 tripartite motif-containing 26 [ Mus musculus (house mouse) ]

Gene ID: 22670, updated on 12-Aug-2019

Summary

Official Symbol
Trim26provided by MGI
Official Full Name
tripartite motif-containing 26provided by MGI
Primary source
MGI:MGI:1337056
See related
Ensembl:ENSMUSG00000024457
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Zfp173; Zfp1736; AI462198
Expression
Ubiquitous expression in ovary adult (RPKM 19.3), spleen adult (RPKM 16.9) and 28 other tissues See more
Orthologs

Genomic context

See Trim26 in Genome Data Viewer
Location:
17 B1; 17 19.16 cM
Exon count:
10
Annotation release Status Assembly Chr Location
108 current GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (36837123..36859398)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (36974086..36996325)

Chromosome 17 - NC_000083.6Genomic Context describing neighboring genes Neighboring gene histocompatibility 2, M region locus 10.5 Neighboring gene histocompatibility 2, M region locus 10.6 Neighboring gene predicted gene, 25973 Neighboring gene tripartite motif-containing 15 Neighboring gene tripartite motif-containing 10

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
immune system process IEA
Inferred from Electronic Annotation
more info
 
innate immune response ISO
Inferred from Sequence Orthology
more info
 
negative regulation of viral entry into host cell ISO
Inferred from Sequence Orthology
more info
 
negative regulation of viral release from host cell ISO
Inferred from Sequence Orthology
more info
 
positive regulation of DNA-binding transcription factor activity ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
tripartite motif-containing protein 26
Names
tripartite motif protein 26
tripartite motif protein TRIM26
zinc finger protein 173
NP_001020770.2
NP_001273655.1
NP_001273656.1
XP_006524276.1
XP_006524277.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001025599.3NP_001020770.2  tripartite motif-containing protein 26

    See identical proteins and their annotated locations for NP_001020770.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) has an alternate splice site in the 5' UTR, compared to variant 3. Variants 1, 3 and 4 encode the same protein.
    Source sequence(s)
    BC037110, BQ176978, CF168373
    Consensus CDS
    CCDS37613.1
    UniProtKB/Swiss-Prot
    Q99PN3
    Related
    ENSMUSP00000060103.7, ENSMUST00000053434.14
    Conserved Domains (3) summary
    smart00336
    Location:97138
    BBOX; B-Box-type zinc finger
    cd15826
    Location:320544
    SPRY_PRY_TRIM15; PRY/SPRY domain in tripartite motif-binding protein 15 (TRIM15)
    cl17238
    Location:1656
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
  2. NM_001286726.1NP_001273655.1  tripartite motif-containing protein 26

    See identical proteins and their annotated locations for NP_001273655.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) represents the longest transcript. Variants 1, 3 and 4 encode the same protein.
    Source sequence(s)
    AK042252, BC037110, BQ176978, CF168373
    Consensus CDS
    CCDS37613.1
    UniProtKB/Swiss-Prot
    Q99PN3
    Conserved Domains (3) summary
    smart00336
    Location:97138
    BBOX; B-Box-type zinc finger
    cd15826
    Location:320544
    SPRY_PRY_TRIM15; PRY/SPRY domain in tripartite motif-binding protein 15 (TRIM15)
    cl17238
    Location:1656
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
  3. NM_001286727.1NP_001273656.1  tripartite motif-containing protein 26

    See identical proteins and their annotated locations for NP_001273656.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) has an alternate splice junction in the 5' UTR, compared to variant 3. Variants 1, 3 and 4 encode the same protein.
    Source sequence(s)
    AK148247, BC037110, BQ176978, CF168373
    Consensus CDS
    CCDS37613.1
    UniProtKB/Swiss-Prot
    Q99PN3
    UniProtKB/TrEMBL
    Q3UFX3
    Related
    ENSMUSP00000114896.1, ENSMUST00000130367.7
    Conserved Domains (3) summary
    smart00336
    Location:97138
    BBOX; B-Box-type zinc finger
    cd15826
    Location:320544
    SPRY_PRY_TRIM15; PRY/SPRY domain in tripartite motif-binding protein 15 (TRIM15)
    cl17238
    Location:1656
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p6 C57BL/6J

Genomic

  1. NC_000083.6 Reference GRCm38.p6 C57BL/6J

    Range
    36837123..36859398
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006524214.3XP_006524277.1  tripartite motif-containing protein 26 isoform X2

    See identical proteins and their annotated locations for XP_006524277.1

    Related
    ENSMUSP00000136651.1, ENSMUST00000179968.7
    Conserved Domains (3) summary
    smart00336
    Location:97138
    BBOX; B-Box-type zinc finger
    pfam15227
    Location:1656
    zf-C3HC4_4; zinc finger of C3HC4-type, RING
    cd15826
    Location:314538
    SPRY_PRY_TRIM15; PRY/SPRY domain in tripartite motif-binding protein 15 (TRIM15)
  2. XM_006524213.3XP_006524276.1  tripartite motif-containing protein 26 isoform X1

    See identical proteins and their annotated locations for XP_006524276.1

    UniProtKB/Swiss-Prot
    Q99PN3
    Conserved Domains (3) summary
    smart00336
    Location:97138
    BBOX; B-Box-type zinc finger
    cd15826
    Location:320544
    SPRY_PRY_TRIM15; PRY/SPRY domain in tripartite motif-binding protein 15 (TRIM15)
    cl17238
    Location:1656
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

Reference GRCm38.p6 129S1/SvImJ

Genomic

  1. NT_187009.1 Reference GRCm38.p6 129S1/SvImJ

    Range
    791770..814022
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCm38.p6 NOD/MrkTac

Genomic

  1. NT_187027.1 Reference GRCm38.p6 NOD/MrkTac

    Range
    3122701..3145202
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCm38.p6 NOD/ShiLtJ

Genomic

  1. NT_187004.1 Reference GRCm38.p6 NOD/ShiLtJ

    Range
    3198332..3220833
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_030698.4: Suppressed sequence

    Description
    NM_030698.4: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
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