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Zbtb17 zinc finger and BTB domain containing 17 [ Mus musculus (house mouse) ]

Gene ID: 22642, updated on 25-Apr-2024

Summary

Official Symbol
Zbtb17provided by MGI
Official Full Name
zinc finger and BTB domain containing 17provided by MGI
Primary source
MGI:MGI:107410
See related
Ensembl:ENSMUSG00000006215 AllianceGenome:MGI:107410
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Lp-1; Miz1; mZ13; Zfp100
Summary
Enables DNA binding activity. Acts upstream of or within ectoderm development; gastrulation with mouth forming second; and positive regulation of transcription, DNA-templated. Located in nucleus. Is expressed in early conceptus; eye; genitourinary system; limb; and trunk somite. Orthologous to human ZBTB17 (zinc finger and BTB domain containing 17). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in whole brain E14.5 (RPKM 15.8), thymus adult (RPKM 15.4) and 28 other tissues See more
Orthologs
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Genomic context

See Zbtb17 in Genome Data Viewer
Location:
4 D3; 4 74.17 cM
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (141171984..141195248)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (141444673..141467937)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene heat shock protein family, member 7 (cardiovascular) Neighboring gene steroid receptor associated and regulated protein Neighboring gene predicted gene, 42337 Neighboring gene STARR-positive B cell enhancer mm9_chr4:141033664-141033965 Neighboring gene spen family transcription repressor Neighboring gene RIKEN cDNA B330016D10 gene Neighboring gene STARR-positive B cell enhancer ABC_E6250 Neighboring gene predicted gene 4123

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
part_of protein-DNA complex ISO
Inferred from Sequence Orthology
more info
 
part_of protein-containing complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
zinc finger and BTB domain-containing protein 17
Names
polyomavirus late initiator promoter-binding protein
zfp-100
zinc finger protein 100
zinc finger protein 151
zinc finger protein Z13

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001378826.1NP_001365755.1  zinc finger and BTB domain-containing protein 17 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL670285
    UniProtKB/TrEMBL
    A6H6B9
    Related
    ENSMUST00000142020.8
    Conserved Domains (5) summary
    COG5048
    Location:322653
    COG5048; FOG: Zn-finger [General function prediction only]
    PRK07003
    Location:115266
    PRK07003; DNA polymerase III subunit gamma/tau
    sd00017
    Location:492512
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:632651
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18206
    Location:2113
    BTB_POZ_ZBTB17_MIZ1; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 17 (ZBTB17)
  2. NM_001378827.1NP_001365756.1  zinc finger and BTB domain-containing protein 17 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AL670285
    UniProtKB/TrEMBL
    A6H6B9
    Conserved Domains (5) summary
    COG3170
    Location:16118
    FimV; Tfp pilus assembly protein FimV [Cell motility, Extracellular structures]
    COG5048
    Location:221552
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:391411
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:531550
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl38908
    Location:137
    BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
  3. NM_001378828.1NP_001365757.1  zinc finger and BTB domain-containing protein 17 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL670285
    UniProtKB/Swiss-Prot
    A2ADB9, Q60699, Q60821
    UniProtKB/TrEMBL
    A6H6B9
    Conserved Domains (5) summary
    COG3170
    Location:92194
    FimV; Tfp pilus assembly protein FimV [Cell motility, Extracellular structures]
    COG5048
    Location:297628
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:467487
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:607626
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18206
    Location:2113
    BTB_POZ_ZBTB17_MIZ1; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 17 (ZBTB17)
  4. NM_009541.2NP_033567.2  zinc finger and BTB domain-containing protein 17 isoform 1

    See identical proteins and their annotated locations for NP_033567.2

    Status: VALIDATED

    Source sequence(s)
    AK134251, BC145821, BY246264
    Consensus CDS
    CCDS18875.1
    UniProtKB/Swiss-Prot
    A2ADB9, Q60699, Q60821
    UniProtKB/TrEMBL
    A6H6B9
    Related
    ENSMUSP00000006377.7, ENSMUST00000006377.13
    Conserved Domains (5) summary
    COG3170
    Location:92194
    FimV; Tfp pilus assembly protein FimV [Cell motility, Extracellular structures]
    COG5048
    Location:297628
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:467487
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:607626
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18206
    Location:2113
    BTB_POZ_ZBTB17_MIZ1; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 17 (ZBTB17)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    141171984..141195248
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)