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Atrnl1 attractin like 1 [ Mus musculus (house mouse) ]

Gene ID: 226255, updated on 12-May-2024

Summary

Official Symbol
Atrnl1provided by MGI
Official Full Name
attractin like 1provided by MGI
Primary source
MGI:MGI:2147749
See related
Ensembl:ENSMUSG00000054843 AllianceGenome:MGI:2147749
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Alp; Atrnl; Atrnlp
Summary
Predicted to enable carbohydrate binding activity. Acts upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be active in basement membrane. Is expressed in several structures, including brain; genitourinary system; liver; lung; and spleen. Orthologous to human ATRNL1 (attractin like 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in colon adult (RPKM 10.7), frontal lobe adult (RPKM 8.8) and 28 other tissues See more
Orthologs
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Genomic context

Location:
19 D2; 19 53.31 cM
Exon count:
33
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (57599248..58121775)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (57610960..58133343)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 6720468P15 gene Neighboring gene STARR-seq mESC enhancer starr_46555 Neighboring gene STARR-seq mESC enhancer starr_46556 Neighboring gene predicted gene, 32932 Neighboring gene STARR-positive B cell enhancer mm9_chr19:57717570-57717871 Neighboring gene STARR-positive B cell enhancer mm9_chr19:57729589-57729890 Neighboring gene STARR-seq mESC enhancer starr_46558 Neighboring gene STARR-seq mESC enhancer starr_46561 Neighboring gene STARR-seq mESC enhancer starr_46562 Neighboring gene STARR-seq mESC enhancer starr_46563 Neighboring gene STARR-seq mESC enhancer starr_46566 Neighboring gene STARR-seq mESC enhancer starr_46567 Neighboring gene predicted gene, 52385 Neighboring gene STARR-seq mESC enhancer starr_46569 Neighboring gene STARR-seq mESC enhancer starr_46571 Neighboring gene predicted gene, 32980 Neighboring gene microRNA 5623 Neighboring gene CapStarr-seq enhancer MGSCv37_chr19:58218359-58218542 Neighboring gene predicted gene, 50287 Neighboring gene STARR-seq mESC enhancer starr_46573 Neighboring gene glial cell line derived neurotrophic factor family receptor alpha 1 Neighboring gene predicted gene, 46650 Neighboring gene predicted gene 10007

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Gene trapped (1) 
  • Targeted (1)  1 citation

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables Notch binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_181415.4NP_852080.3  attractin-like protein 1 precursor

    See identical proteins and their annotated locations for NP_852080.3

    Status: VALIDATED

    Source sequence(s)
    AK147492, AY688677
    Consensus CDS
    CCDS29928.1
    UniProtKB/Swiss-Prot
    Q3UHB0, Q68HV2, Q6A051, Q80VI3, Q8BKS4, Q8K0P5
    Related
    ENSMUSP00000076514.6, ENSMUST00000077282.7
    Conserved Domains (8) summary
    cd03597
    Location:747873
    CLECT_attractin_like; C-type lectin-like domain (CTLD) of the type found in human and mouse attractin (AtrN) and attractin-like protein (ALP)
    cd00041
    Location:92207
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    cd00055
    Location:10121057
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    sd00038
    Location:520573
    Kelch; KELCH repeat [structural motif]
    pfam01437
    Location:888937
    PSI; Plexin repeat
    pfam13418
    Location:467513
    Kelch_4; Galactose oxidase, central domain
    pfam13854
    Location:351391
    Kelch_5; Kelch motif
    cl19567
    Location:234279
    DSL; Delta serrate ligand

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    57599248..58121775
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030250921.2XP_030106781.1  attractin-like protein 1 isoform X7

    Conserved Domains (4) summary
    cd03597
    Location:215341
    CLECT_attractin_like; C-type lectin-like domain (CTLD) of the type found in human and mouse attractin (AtrN) and attractin-like protein (ALP)
    cd00055
    Location:480525
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    pfam01437
    Location:356404
    PSI; Plexin repeat
    pfam13854
    Location:4881
    Kelch_5; Kelch motif
  2. XM_011247244.2XP_011245546.1  attractin-like protein 1 isoform X3

    Conserved Domains (9) summary
    cd03597
    Location:704830
    CLECT_attractin_like; C-type lectin-like domain (CTLD) of the type found in human and mouse attractin (AtrN) and attractin-like protein (ALP)
    PLN02153
    Location:410556
    PLN02153; epithiospecifier protein
    PHA03098
    Location:272410
    PHA03098; kelch-like protein; Provisional
    cd00041
    Location:92162
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    cd00055
    Location:9691014
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    sd00038
    Location:477530
    Kelch; KELCH repeat [structural motif]
    pfam01414
    Location:178236
    DSL; Delta serrate ligand
    pfam01437
    Location:845893
    PSI; Plexin repeat
    pfam13854
    Location:308348
    Kelch_5; Kelch motif
  3. XM_006527049.4XP_006527112.1  attractin-like protein 1 isoform X1

    Conserved Domains (9) summary
    cd03597
    Location:747873
    CLECT_attractin_like; C-type lectin-like domain (CTLD) of the type found in human and mouse attractin (AtrN) and attractin-like protein (ALP)
    PLN02153
    Location:453599
    PLN02153; epithiospecifier protein
    PHA03098
    Location:315453
    PHA03098; kelch-like protein; Provisional
    cd00041
    Location:92207
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    cd00055
    Location:10121057
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    sd00038
    Location:520573
    Kelch; KELCH repeat [structural motif]
    pfam01414
    Location:221279
    DSL; Delta serrate ligand
    pfam01437
    Location:888936
    PSI; Plexin repeat
    pfam13854
    Location:351391
    Kelch_5; Kelch motif
  4. XM_036161583.1XP_036017476.1  attractin-like protein 1 isoform X2

    Conserved Domains (9) summary
    cd03597
    Location:747873
    CLECT_attractin_like; C-type lectin-like domain (CTLD) of the type found in human and mouse attractin (AtrN) and attractin-like protein (ALP)
    PLN02153
    Location:453599
    PLN02153; epithiospecifier protein
    PHA03098
    Location:315453
    PHA03098; kelch-like protein; Provisional
    cd00041
    Location:92207
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    cd00055
    Location:10121057
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    sd00038
    Location:520573
    Kelch; KELCH repeat [structural motif]
    pfam01437
    Location:888937
    PSI; Plexin repeat
    pfam13854
    Location:351391
    Kelch_5; Kelch motif
    cl19567
    Location:234279
    DSL; Delta serrate ligand
  5. XM_036161584.1XP_036017477.1  attractin-like protein 1 isoform X4

    Conserved Domains (9) summary
    cd03597
    Location:747873
    CLECT_attractin_like; C-type lectin-like domain (CTLD) of the type found in human and mouse attractin (AtrN) and attractin-like protein (ALP)
    PLN02153
    Location:453599
    PLN02153; epithiospecifier protein
    PHA03098
    Location:315453
    PHA03098; kelch-like protein; Provisional
    cd00041
    Location:92207
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    cd00055
    Location:10121057
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    sd00038
    Location:520573
    Kelch; KELCH repeat [structural motif]
    pfam01437
    Location:888937
    PSI; Plexin repeat
    pfam13854
    Location:351391
    Kelch_5; Kelch motif
    cl19567
    Location:234279
    DSL; Delta serrate ligand
  6. XM_006527051.4XP_006527114.1  attractin-like protein 1 isoform X5

    Conserved Domains (9) summary
    cd03597
    Location:747873
    CLECT_attractin_like; C-type lectin-like domain (CTLD) of the type found in human and mouse attractin (AtrN) and attractin-like protein (ALP)
    PLN02153
    Location:453599
    PLN02153; epithiospecifier protein
    PLN02193
    Location:299386
    PLN02193; nitrile-specifier protein
    cd00041
    Location:92207
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    cd00055
    Location:10121057
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    sd00038
    Location:520573
    Kelch; KELCH repeat [structural motif]
    pfam01414
    Location:221279
    DSL; Delta serrate ligand
    pfam01437
    Location:888936
    PSI; Plexin repeat
    pfam13854
    Location:351391
    Kelch_5; Kelch motif
  7. XM_006527052.4XP_006527115.1  attractin-like protein 1 isoform X6

    Conserved Domains (9) summary
    cd03597
    Location:747873
    CLECT_attractin_like; C-type lectin-like domain (CTLD) of the type found in human and mouse attractin (AtrN) and attractin-like protein (ALP)
    PLN02153
    Location:453599
    PLN02153; epithiospecifier protein
    PHA03098
    Location:315453
    PHA03098; kelch-like protein; Provisional
    cd00041
    Location:92207
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    cd00055
    Location:10121057
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    sd00038
    Location:520573
    Kelch; KELCH repeat [structural motif]
    pfam01414
    Location:221279
    DSL; Delta serrate ligand
    pfam01437
    Location:888936
    PSI; Plexin repeat
    pfam13854
    Location:351391
    Kelch_5; Kelch motif

RNA

  1. XR_001782587.2 RNA Sequence