U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Snx32 sorting nexin 32 [ Mus musculus (house mouse) ]

Gene ID: 225861, updated on 8-Dec-2022

Summary

Go to the top of the page Help
Official Symbol
Snx32provided by MGI
Official Full Name
sorting nexin 32provided by MGI
Primary source
MGI:MGI:2444704
See related
Ensembl:ENSMUSG00000056185 AllianceGenome:MGI:2444704
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Snx6b; B930037P14Rik
Summary
Predicted to enable phosphatidylinositol binding activity. Predicted to be involved in retrograde transport, endosome to Golgi. Predicted to act upstream of or within protein transport. Predicted to be active in endosome. Orthologous to human SNX32 (sorting nexin 32). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in cerebellum adult (RPKM 35.4), frontal lobe adult (RPKM 30.4) and 21 other tissues See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Snx32 in Genome Data Viewer
Location:
19; 19 A
Exon count:
14
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (5545302..5560741, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (5495274..5510708, complement)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene MUS81 structure-specific endonuclease subunit Neighboring gene cofilin 1, non-muscle Neighboring gene NSE3 homolog, SMC5-SMC6 complex component like Neighboring gene predicted gene, 31166 Neighboring gene ovo like zinc finger 1 Neighboring gene adaptor-related protein complex 5, beta 1 subunit

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  2. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
  3. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (13) citations in PubMed

See citations in PubMed for homologs of this gene provided by HomoloGene

GeneRIFs: Gene References Into Functions

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables phosphatidylinositol binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in endosome IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
sorting nexin-32
Names
sortin nexin-6B
sorting nexin-6B

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001024560.3 → NP_001019731.1  sorting nexin-32 isoform1

    See identical proteins and their annotated locations for NP_001019731.1

    Status: VALIDATED

    Source sequence(s)
    AI846187, BB597960, BC048922
    Consensus CDS
    CCDS29468.1
    UniProtKB/Swiss-Prot
    Q80ZJ7
    Related
    ENSMUSP00000070915.5, ENSMUST00000070172.6
    Conserved Domains (2) summary
    cd07621
    Location:181 → 401
    BAR_SNX5_6; The Bin/Amphiphysin/Rvs (BAR) domain of Sorting Nexins 5 and 6
    cl02563
    Location:27 → 164
    PX_domain; The Phox Homology domain, a phosphoinositide binding module

  2. NM_001362042.1 → NP_001348971.1  sorting nexin-32 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AI846187, AK047234, AK143441, BB597960
    Consensus CDS
    CCDS89312.1
    UniProtKB/TrEMBL
    A0A494B972
    Related
    ENSMUSP00000157473.2, ENSMUST00000237111.2
    Conserved Domains (2) summary
    cd07621
    Location:181 → 393
    BAR_SNX5_6; The Bin/Amphiphysin/Rvs (BAR) domain of Sorting Nexins 5 and 6
    cl02563
    Location:27 → 164
    PX_domain; The Phox Homology domain, a phosphoinositide binding module

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    5545302..5560741 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011248617.4 → XP_011246919.1  sorting nexin-32 isoform X1

    Conserved Domains (2) summary
    cd06892
    Location:27 → 164
    PX_SNX5_like; The phosphoinositide binding Phox Homology domain of Sorting Nexins 5 and 6
    cl12013
    Location:181 → 305
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

  2. XM_030250871.2 → XP_030106731.1  sorting nexin-32 isoform X4

    Conserved Domains (2) summary
    cd07621
    Location:62 → 282
    BAR_SNX5_6; The Bin/Amphiphysin/Rvs (BAR) domain of Sorting Nexins 5 and 6
    cl02563
    Location:1 → 45
    PX_domain; The Phox Homology domain, a phosphoinositide binding module

  3. XM_030250870.2 → XP_030106730.1  sorting nexin-32 isoform X3

    Conserved Domains (2) summary
    cd07621
    Location:62 → 274
    BAR_SNX5_6; The Bin/Amphiphysin/Rvs (BAR) domain of Sorting Nexins 5 and 6
    cl02563
    Location:1 → 45
    PX_domain; The Phox Homology domain, a phosphoinositide binding module

  4. XM_011248618.3 → XP_011246920.1  sorting nexin-32 isoform X2

    Conserved Domains (2) summary
    cl02563
    Location:1 → 45
    PX_domain; The Phox Homology domain, a phosphoinositide binding module
    cl12013
    Location:62 → 186
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

  5. XM_036161522.1 → XP_036017415.1  sorting nexin-32 isoform X3

    Conserved Domains (2) summary
    cd07621
    Location:62 → 274
    BAR_SNX5_6; The Bin/Amphiphysin/Rvs (BAR) domain of Sorting Nexins 5 and 6
    cl02563
    Location:1 → 45
    PX_domain; The Phox Homology domain, a phosphoinositide binding module

  6. XM_036161521.1 → XP_036017414.1  sorting nexin-32 isoform X2

    Conserved Domains (2) summary
    cl02563
    Location:1 → 45
    PX_domain; The Phox Homology domain, a phosphoinositide binding module
    cl12013
    Location:62 → 186
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

RNA

  1. XR_388254.5 RNA Sequence

  2. XR_004940135.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q80ZJ7.1 GenPept UniProtKB/Swiss-Prot:Q80ZJ7

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous