Ino80c INO80 complex subunit C [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Ino80cprovided by MGI
Official Full Name: INO80 complex subunit Cprovided by MGI
Primary source: MGI:MGI:2443014
See related: Ensembl:ENSMUSG00000047989 AllianceGenome:MGI:2443014
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: D030070L09Rik
Summary: Predicted to be involved in chromatin remodeling. Predicted to act upstream of or within DNA recombination and DNA repair. Predicted to be located in nucleus. Predicted to be part of Ino80 complex and MLL1 complex. Orthologous to human INO80C (INO80 complex subunit C). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in testis adult (RPKM 12.6), placenta adult (RPKM 10.6) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 18; 18 A2

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
109	current	GRCm39 (GCF_000001635.27)	18	NC_000084.7 (24237818..24254876, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	18	NC_000084.6 (24104761..24121819, complement)

Chromosome 18 - NC_000084.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)

General gene information

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Markers

NoName (e-PCR)
- UniSTS:237339

RH124624 (e-PCR)
- UniSTS:161446

RH125712 (e-PCR)
- UniSTS:162475

NoName (e-PCR)
- UniSTS:237751

MARC_13470-13471:1002300368:2 (e-PCR)
- UniSTS:267502

Homology

Homologs of the Ino80c gene: The Ino80c gene is conserved in human, chimpanzee, dog, cow, rat, chicken, zebrafish, and mosquito.
Orthologs from Annotation Pipeline: 494 organisms have orthologs with human gene Ino80c
Orthologs

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within DNA damage response	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within DNA recombination	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within DNA repair	IEA Inferred from Electronic Annotation more info
involved_in chromatin remodeling	IBA Inferred from Biological aspect of Ancestor more info	PubMed
involved_in chromatin remodeling	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of DNA repair	IDA Inferred from Direct Assay more info	PubMed
involved_in positive regulation of DNA-templated transcription	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of telomere maintenance in response to DNA damage	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of DNA repair	IDA Inferred from Direct Assay more info	PubMed
involved_in regulation of DNA replication	ISO Inferred from Sequence Orthology more info
involved_in regulation of DNA strand elongation	ISO Inferred from Sequence Orthology more info
involved_in regulation of cell cycle	ISO Inferred from Sequence Orthology more info
involved_in regulation of chromosome organization	ISO Inferred from Sequence Orthology more info
involved_in regulation of embryonic development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in telomere maintenance	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
part_of Ino80 complex	IBA Inferred from Biological aspect of Ancestor more info	PubMed
part_of Ino80 complex	ISO Inferred from Sequence Orthology more info
part_of MLL1 complex	ISO Inferred from Sequence Orthology more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: INO80 complex subunit C

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.