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Pex6 peroxisomal biogenesis factor 6 [ Mus musculus (house mouse) ]

Gene ID: 224824, updated on 31-Jan-2019

Summary

Official Symbol
Pex6provided by MGI
Official Full Name
peroxisomal biogenesis factor 6provided by MGI
Primary source
MGI:MGI:2385054
See related
Ensembl:ENSMUSG00000002763
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
PAF-2; AI132582; D130055I09Rik
Expression
Ubiquitous expression in adrenal adult (RPKM 85.9), ovary adult (RPKM 56.9) and 28 other tissues See more
Orthologs

Genomic context

See Pex6 in Genome Data Viewer
Location:
17; 17 C
Exon count:
17
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 17 NC_000083.6 (46711463..46725541)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (46848412..46862490)

Chromosome 17 - NC_000083.6Genomic Context describing neighboring genes Neighboring gene kelch domain containing 3 Neighboring gene male enhanced antigen 1 Neighboring gene protein phosphatase 2, regulatory subunit B', delta Neighboring gene glycine N-methyltransferase Neighboring gene canopy FGF signaling regulator 3

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Pathways from BioSystems

  • Peroxisome, organism-specific biosystem (from KEGG)
    Peroxisome, organism-specific biosystemPeroxisomes are essential organelles that play a key role in redox signalling and lipid homeostasis. They contribute to many crucial metabolic processes such as fatty acid oxidation, biosynthesis of ...
  • Peroxisome, conserved biosystem (from KEGG)
    Peroxisome, conserved biosystemPeroxisomes are essential organelles that play a key role in redox signalling and lipid homeostasis. They contribute to many crucial metabolic processes such as fatty acid oxidation, biosynthesis of ...

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC6455, KIAA4177

Gene Ontology Provided by MGI

Function Evidence Code Pubs
ATP binding ISO
Inferred from Sequence Orthology
more info
 
ATPase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ATPase activity ISO
Inferred from Sequence Orthology
more info
 
ATPase activity, coupled ISO
Inferred from Sequence Orthology
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
protein C-terminus binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein-containing complex binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
peroxisome organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
peroxisome organization ISO
Inferred from Sequence Orthology
more info
 
protein import into peroxisome matrix IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein import into peroxisome matrix, translocation ISO
Inferred from Sequence Orthology
more info
 
protein stabilization ISO
Inferred from Sequence Orthology
more info
 
protein targeting to peroxisome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein targeting to peroxisome ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cell projection IEA
Inferred from Electronic Annotation
more info
 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytosol ISO
Inferred from Sequence Orthology
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
peroxisomal membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
peroxisomal membrane ISO
Inferred from Sequence Orthology
more info
 
peroxisome ISO
Inferred from Sequence Orthology
more info
 
photoreceptor cell cilium IDA
Inferred from Direct Assay
more info
PubMed 
photoreceptor cell cilium ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
peroxisome assembly factor 2
Names
peroxin-6
peroxisomal-type ATPase 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_145488.2NP_663463.1  peroxisome assembly factor 2

    See identical proteins and their annotated locations for NP_663463.1

    Status: VALIDATED

    Source sequence(s)
    CT030702
    Consensus CDS
    CCDS28837.1
    UniProtKB/Swiss-Prot
    Q99LC9
    Related
    ENSMUSP00000002840.8, ENSMUST00000002840.8
    Conserved Domains (2) summary
    COG0464
    Location:464968
    SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]
    pfam00004
    Location:744872
    AAA; ATPase family associated with various cellular activities (AAA)

RNA

  1. NR_157369.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AK143173, AK220525, CT030702

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000083.6 Reference GRCm38.p4 C57BL/6J

    Range
    46711463..46725541
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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