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Abcf1 ATP-binding cassette, sub-family F member 1 [ Mus musculus (house mouse) ]

Gene ID: 224742, updated on 12-May-2024

Summary

Official Symbol
Abcf1provided by MGI
Official Full Name
ATP-binding cassette, sub-family F member 1provided by MGI
Primary source
MGI:MGI:1351658
See related
Ensembl:ENSMUSG00000038762 AllianceGenome:MGI:1351658
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Abc50; GCN20; D17Wsu166e
Summary
Predicted to enable ATP binding activity; ribosome binding activity; and translation activator activity. Predicted to be involved in positive regulation of translation and translational initiation. Predicted to be located in cytosol; nucleus; and polysomal ribosome. Is expressed in several structures, including eye; genitourinary system; immune system; lung; and nervous system. Orthologous to human ABCF1 (ATP binding cassette subfamily F member 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 41.9), CNS E11.5 (RPKM 33.3) and 28 other tissues See more
Orthologs
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Genomic context

See Abcf1 in Genome Data Viewer
Location:
17 B1; 17 18.8 cM
Exon count:
23
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (36267711..36280642, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (35956819..35969750, complement)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_42482 Neighboring gene STARR-positive B cell enhancer ABC_E11644 Neighboring gene ring-box 1, pseudogene Neighboring gene STARR-seq mESC enhancer starr_42484 Neighboring gene protein phosphatase 1, regulatory subunit 10 pseudogene Neighboring gene microRNA 877 Neighboring gene STARR-positive B cell enhancer ABC_E8674 Neighboring gene predicted gene, 32655 Neighboring gene proline-rich polypeptide 3 Neighboring gene guanine nucleotide binding protein-like 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Gene trapped (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATP binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables ATP binding ISO
Inferred from Sequence Orthology
more info
 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables ribosome binding ISO
Inferred from Sequence Orthology
more info
 
enables translation activator activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in positive regulation of translation ISO
Inferred from Sequence Orthology
more info
 
involved_in translational initiation ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in nuclear envelope ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
located_in ribosome ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
ATP-binding cassette sub-family F member 1
Names
ATP-binding cassette, sub-family F (GCN20), member 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_013854.1NP_038882.1  ATP-binding cassette sub-family F member 1

    See identical proteins and their annotated locations for NP_038882.1

    Status: VALIDATED

    Source sequence(s)
    BC063094
    Consensus CDS
    CCDS28713.1
    UniProtKB/Swiss-Prot
    Q6NV71, Q6P542
    UniProtKB/TrEMBL
    Q5RL55
    Related
    ENSMUSP00000036881.9, ENSMUST00000043757.15
    Conserved Domains (2) summary
    cd03221
    Location:296517
    ABCF_EF-3; ATP-binding cassette domain of elongation factor 3, subfamily F
    COG0488
    Location:294825
    Uup; ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    36267711..36280642 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)