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Bag6 BCL2-associated athanogene 6 [ Mus musculus (house mouse) ]

Gene ID: 224727, updated on 14-Jan-2023

Summary

Official Symbol
Bag6provided by MGI
Official Full Name
BCL2-associated athanogene 6provided by MGI
Primary source
MGI:MGI:1919439
See related
Ensembl:ENSMUSG00000024392 AllianceGenome:MGI:1919439
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
G3; Bat3; BAG-6; Scythe; D17H6S52E; 2410045D21Rik
Summary
Enables Hsp70 protein binding activity; polyubiquitin modification-dependent protein binding activity; and proteasome binding activity. Involved in several processes, including animal organ development; protein stabilization; and synaptonemal complex assembly. Acts upstream of or within negative regulation of apoptotic process. Located in cytosol and nucleus. Is expressed in palatal shelf epithelium. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma and osteoarthritis. Orthologous to human BAG6 (BAG cochaperone 6). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 225.5), adrenal adult (RPKM 122.8) and 28 other tissues See more
Orthologs
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Genomic context

See Bag6 in Genome Data Viewer
Location:
17 B1; 17 18.59 cM
Exon count:
28
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (35354132..35366297)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (35135156..35147321)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene DNA segment, Chr 17, human D6S53E Neighboring gene apolipoprotein M Neighboring gene proline-rich coiled-coil 2A Neighboring gene predicted gene, 23442 Neighboring gene allograft inflammatory factor 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2)  1 citation
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables Hsp70 protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
enables misfolded protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables misfolded protein binding ISO
Inferred from Sequence Orthology
more info
 
enables polyubiquitin modification-dependent protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables polyubiquitin modification-dependent protein binding IDA
Inferred from Direct Assay
more info
PubMed 
enables proteasome binding IDA
Inferred from Direct Assay
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables ribosome binding ISO
Inferred from Sequence Orthology
more info
 
enables signaling receptor binding ISO
Inferred from Sequence Orthology
more info
 
enables ubiquitin protein ligase binding ISO
Inferred from Sequence Orthology
more info
 
enables ubiquitin-specific protease binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in ER-associated misfolded protein catabolic process ISO
Inferred from Sequence Orthology
more info
 
involved_in antigen processing and presentation of peptide antigen via MHC class I TAS
Traceable Author Statement
more info
PubMed 
involved_in apoptotic process ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within apoptotic process RCA
inferred from Reviewed Computational Analysis
more info
PubMed 
involved_in brain development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within cell differentiation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within chromatin organization IEA
Inferred from Electronic Annotation
more info
 
involved_in endoplasmic reticulum stress-induced pre-emptive quality control ISO
Inferred from Sequence Orthology
more info
 
involved_in immune response-activating cell surface receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within immune system process IEA
Inferred from Electronic Annotation
more info
 
involved_in internal peptidyl-lysine acetylation ISO
Inferred from Sequence Orthology
more info
 
involved_in intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator ISO
Inferred from Sequence Orthology
more info
 
involved_in intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in kidney development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in lung development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in maintenance of unfolded protein involved in ERAD pathway ISO
Inferred from Sequence Orthology
more info
 
involved_in natural killer cell activation ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within negative regulation of apoptotic process IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in negative regulation of proteasomal ubiquitin-dependent protein catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of proteolysis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of ERAD pathway ISO
Inferred from Sequence Orthology
more info
 
involved_in post-translational protein targeting to endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
 
involved_in proteasomal protein catabolic process ISO
Inferred from Sequence Orthology
more info
 
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein stabilization IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within regulation of apoptotic process RCA
inferred from Reviewed Computational Analysis
more info
PubMed 
involved_in regulation of embryonic development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of protein stability ISO
Inferred from Sequence Orthology
more info
 
involved_in spermatogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in synaptonemal complex assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in tail-anchored membrane protein insertion into ER membrane ISO
Inferred from Sequence Orthology
more info
 
involved_in ubiquitin-dependent ERAD pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in ubiquitin-dependent ERAD pathway ISO
Inferred from Sequence Orthology
more info
 
involved_in ubiquitin-dependent protein catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in ubiquitin-dependent protein catabolic process ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
part_of BAT3 complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of BAT3 complex ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol NAS
Non-traceable Author Statement
more info
PubMed 
located_in extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
located_in membrane ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
large proline-rich protein BAG6
Names
BAG family molecular chaperone regulator 6
HLA-B-associated transcript 3
large proline-rich protein BAT3
protein Scythe

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001252468.2NP_001239397.1  large proline-rich protein BAG6 isoform 2

    See identical proteins and their annotated locations for NP_001239397.1

    Status: VALIDATED

    Source sequence(s)
    CR974444
    Consensus CDS
    CCDS57073.1
    UniProtKB/TrEMBL
    Q3UF95
    Related
    ENSMUSP00000129324.3, ENSMUST00000166426.9
    Conserved Domains (3) summary
    PRK07764
    Location:9091100
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:260374
    DUF3538; Domain of unknown function (DUF3538)
  2. NM_001252469.2NP_001239398.1  large proline-rich protein BAG6 isoform 3

    Status: VALIDATED

    Source sequence(s)
    CR974444
    Consensus CDS
    CCDS57072.1
    UniProtKB/TrEMBL
    G3UZT6
    Related
    ENSMUSP00000134628.2, ENSMUST00000173550.8
    Conserved Domains (3) summary
    PRK07764
    Location:9441122
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:260374
    DUF3538; Domain of unknown function (DUF3538)
  3. NM_001372260.1NP_001359189.1  large proline-rich protein BAG6 isoform 4

    Status: VALIDATED

    Source sequence(s)
    CR974444
    Conserved Domains (3) summary
    PRK07764
    Location:9631154
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:278392
    DUF3538; Domain of unknown function (DUF3538)
  4. NM_001372261.1NP_001359190.1  large proline-rich protein BAG6 isoform 5

    Status: VALIDATED

    Source sequence(s)
    CR974444
    Conserved Domains (3) summary
    PRK07764
    Location:9621153
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:278392
    DUF3538; Domain of unknown function (DUF3538)
  5. NM_001372262.1NP_001359191.1  large proline-rich protein BAG6 isoform 6

    Status: VALIDATED

    Source sequence(s)
    CR974444
    Conserved Domains (3) summary
    PRK07764
    Location:9451136
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:260374
    DUF3538; Domain of unknown function (DUF3538)
  6. NM_001372265.1NP_001359194.1  large proline-rich protein BAG6 isoform 7

    Status: VALIDATED

    Source sequence(s)
    CR974444
    Conserved Domains (3) summary
    PRK07764
    Location:9271147
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:278392
    DUF3538; Domain of unknown function (DUF3538)
  7. NM_001372266.1NP_001359195.1  large proline-rich protein BAG6 isoform 12

    Status: VALIDATED

    Source sequence(s)
    CR974444
    Conserved Domains (3) summary
    PRK07764
    Location:9271105
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:278392
    DUF3538; Domain of unknown function (DUF3538)
  8. NM_001372267.1NP_001359196.1  large proline-rich protein BAG6 isoform 1

    Status: VALIDATED

    Source sequence(s)
    CR974444
    UniProtKB/Swiss-Prot
    Q8SNA3
    Conserved Domains (3) summary
    PRK07764
    Location:9271118
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:278392
    DUF3538; Domain of unknown function (DUF3538)
  9. NM_001372268.1NP_001359197.1  large proline-rich protein BAG6 isoform 1

    Status: VALIDATED

    Source sequence(s)
    CR974444
    Consensus CDS
    CCDS28688.1
    UniProtKB/Swiss-Prot
    Q8SNA3
    Conserved Domains (3) summary
    PRK07764
    Location:9271118
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:278392
    DUF3538; Domain of unknown function (DUF3538)
  10. NM_001372269.1NP_001359198.1  large proline-rich protein BAG6 isoform 18

    Status: VALIDATED

    Source sequence(s)
    CR974444
    Conserved Domains (3) summary
    PRK07764
    Location:9261117
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:278392
    DUF3538; Domain of unknown function (DUF3538)
  11. NM_001372270.1NP_001359199.1  large proline-rich protein BAG6 isoform 18

    Status: VALIDATED

    Source sequence(s)
    CR974444
    Conserved Domains (3) summary
    PRK07764
    Location:9261117
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:278392
    DUF3538; Domain of unknown function (DUF3538)
  12. NM_001372271.1NP_001359200.1  large proline-rich protein BAG6 isoform 18

    Status: VALIDATED

    Source sequence(s)
    CR974444
    Conserved Domains (3) summary
    PRK07764
    Location:9261117
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:278392
    DUF3538; Domain of unknown function (DUF3538)
  13. NM_001372272.1NP_001359201.1  large proline-rich protein BAG6 isoform 18

    Status: VALIDATED

    Source sequence(s)
    CR974444
    Conserved Domains (3) summary
    PRK07764
    Location:9261117
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:278392
    DUF3538; Domain of unknown function (DUF3538)
  14. NM_001372273.1NP_001359202.1  large proline-rich protein BAG6 isoform 8

    Status: VALIDATED

    Source sequence(s)
    CR974444
    Conserved Domains (3) summary
    PRK07764
    Location:9261146
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:278392
    DUF3538; Domain of unknown function (DUF3538)
  15. NM_001372274.1NP_001359203.1  large proline-rich protein BAG6 isoform 8

    Status: VALIDATED

    Source sequence(s)
    CR974444
    Conserved Domains (3) summary
    PRK07764
    Location:9261146
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:278392
    DUF3538; Domain of unknown function (DUF3538)
  16. NM_001372275.1NP_001359204.1  large proline-rich protein BAG6 isoform 9

    Status: VALIDATED

    Source sequence(s)
    CR974444
    Conserved Domains (3) summary
    PRK07764
    Location:9631141
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:278392
    DUF3538; Domain of unknown function (DUF3538)
  17. NM_001372276.1NP_001359205.1  large proline-rich protein BAG6 isoform 10

    Status: VALIDATED

    Source sequence(s)
    CR974444
    Conserved Domains (3) summary
    PRK07764
    Location:9621140
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:278392
    DUF3538; Domain of unknown function (DUF3538)
  18. NM_001372277.1NP_001359206.1  large proline-rich protein BAG6 isoform 10

    Status: VALIDATED

    Source sequence(s)
    CR974444
    Related
    ENSMUSP00000134425.2, ENSMUST00000174281.9
    Conserved Domains (3) summary
    PRK07764
    Location:9621140
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:278392
    DUF3538; Domain of unknown function (DUF3538)
  19. NM_001372278.1NP_001359207.1  large proline-rich protein BAG6 isoform 10

    Status: VALIDATED

    Source sequence(s)
    CR974444
    Conserved Domains (3) summary
    PRK07764
    Location:9621140
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:278392
    DUF3538; Domain of unknown function (DUF3538)
  20. NM_001372279.1NP_001359208.1  large proline-rich protein BAG6 isoform 2

    Status: VALIDATED

    Source sequence(s)
    CR974444
    UniProtKB/TrEMBL
    Q3UF95
    Conserved Domains (3) summary
    PRK07764
    Location:9091100
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:260374
    DUF3538; Domain of unknown function (DUF3538)
  21. NM_001372280.1NP_001359209.1  large proline-rich protein BAG6 isoform 11

    Status: VALIDATED

    Source sequence(s)
    CR974444
    Conserved Domains (3) summary
    PRK07764
    Location:9081099
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:260374
    DUF3538; Domain of unknown function (DUF3538)
  22. NM_001372281.1NP_001359210.1  large proline-rich protein BAG6 isoform 11

    Status: VALIDATED

    Source sequence(s)
    CR974444
    Conserved Domains (3) summary
    PRK07764
    Location:9081099
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:260374
    DUF3538; Domain of unknown function (DUF3538)
  23. NM_001372282.1NP_001359211.1  large proline-rich protein BAG6 isoform 11

    Status: VALIDATED

    Source sequence(s)
    CR974444
    Conserved Domains (3) summary
    PRK07764
    Location:9081099
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:260374
    DUF3538; Domain of unknown function (DUF3538)
  24. NM_001372283.1NP_001359212.1  large proline-rich protein BAG6 isoform 3

    Status: VALIDATED

    Source sequence(s)
    CR974444
    UniProtKB/TrEMBL
    G3UZT6
    Conserved Domains (3) summary
    PRK07764
    Location:9441122
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:260374
    DUF3538; Domain of unknown function (DUF3538)
  25. NM_001372284.1NP_001359213.1  large proline-rich protein BAG6 isoform 12

    Status: VALIDATED

    Source sequence(s)
    CR974444
    Conserved Domains (3) summary
    PRK07764
    Location:9271105
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:278392
    DUF3538; Domain of unknown function (DUF3538)
  26. NM_001372285.1NP_001359214.1  large proline-rich protein BAG6 isoform 12

    Status: VALIDATED

    Source sequence(s)
    CR974444
    Conserved Domains (3) summary
    PRK07764
    Location:9271105
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:278392
    DUF3538; Domain of unknown function (DUF3538)
  27. NM_001372286.1NP_001359215.1  large proline-rich protein BAG6 isoform 13

    Status: VALIDATED

    Source sequence(s)
    CR974444
    Conserved Domains (3) summary
    PRK07764
    Location:9261104
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:278392
    DUF3538; Domain of unknown function (DUF3538)
  28. NM_001372287.1NP_001359216.1  large proline-rich protein BAG6 isoform 13

    Status: VALIDATED

    Source sequence(s)
    CR974444
    Conserved Domains (3) summary
    PRK07764
    Location:9261104
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:278392
    DUF3538; Domain of unknown function (DUF3538)
  29. NM_001372288.1NP_001359217.1  large proline-rich protein BAG6 isoform 14

    Status: VALIDATED

    Source sequence(s)
    CR974444
    Conserved Domains (3) summary
    PRK07764
    Location:9261064
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:278392
    DUF3538; Domain of unknown function (DUF3538)
  30. NM_001372289.1NP_001359218.1  large proline-rich protein BAG6 isoform 15

    Status: VALIDATED

    Source sequence(s)
    CR974444
    Conserved Domains (3) summary
    PRK07764
    Location:9081086
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:260374
    DUF3538; Domain of unknown function (DUF3538)
  31. NM_001372290.1NP_001359219.1  large proline-rich protein BAG6 isoform 15

    Status: VALIDATED

    Source sequence(s)
    CR974444
    Related
    ENSMUSP00000134175.2, ENSMUST00000172571.8
    Conserved Domains (3) summary
    PRK07764
    Location:9081086
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:260374
    DUF3538; Domain of unknown function (DUF3538)
  32. NM_001372291.1NP_001359220.1  large proline-rich protein BAG6 isoform 16

    Status: VALIDATED

    Source sequence(s)
    CR974444
    Conserved Domains (3) summary
    PRK07764
    Location:9011079
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:278392
    DUF3538; Domain of unknown function (DUF3538)
  33. NM_001404327.1NP_001391256.1  large proline-rich protein BAG6 isoform 4

    Status: VALIDATED

    Source sequence(s)
    CR974444
  34. NM_001404328.1NP_001391257.1  large proline-rich protein BAG6 isoform 5

    Status: VALIDATED

    Source sequence(s)
    CR974444
  35. NM_001404329.1NP_001391258.1  large proline-rich protein BAG6 isoform 5

    Status: VALIDATED

    Source sequence(s)
    CR974444
  36. NM_001404330.1NP_001391259.1  large proline-rich protein BAG6 isoform 17

    Status: VALIDATED

    Source sequence(s)
    CR974444
  37. NM_001404331.1NP_001391260.1  large proline-rich protein BAG6 isoform 9

    Status: VALIDATED

    Source sequence(s)
    CR974444
  38. NM_057171.3NP_476512.1  large proline-rich protein BAG6 isoform 1

    See identical proteins and their annotated locations for NP_476512.1

    Status: VALIDATED

    Source sequence(s)
    CR974444
    Consensus CDS
    CCDS28688.1
    UniProtKB/Swiss-Prot
    Q8SNA3, Q9Z1R2
    UniProtKB/TrEMBL
    Q3UF95
    Related
    ENSMUSP00000025250.8, ENSMUST00000025250.14
    Conserved Domains (3) summary
    PRK07764
    Location:9271118
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:278392
    DUF3538; Domain of unknown function (DUF3538)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    35354132..35366297
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006524117.4XP_006524180.1  large proline-rich protein BAG6 isoform X9

    See identical proteins and their annotated locations for XP_006524180.1

    Conserved Domains (3) summary
    PRK07764
    Location:9451136
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:260374
    DUF3538; Domain of unknown function (DUF3538)
  2. XM_030249713.1XP_030105573.1  large proline-rich protein BAG6 isoform X10

    Conserved Domains (3) summary
    PRK07764
    Location:9441135
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:260374
    DUF3538; Domain of unknown function (DUF3538)
  3. XM_036160544.1XP_036016437.1  large proline-rich protein BAG6 isoform X12

    Conserved Domains (3) summary
    PRK07764
    Location:9631141
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:278392
    DUF3538; Domain of unknown function (DUF3538)
  4. XM_030249708.2XP_030105568.1  large proline-rich protein BAG6 isoform X5

    Conserved Domains (3) summary
    PRK07764
    Location:9621153
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:278392
    DUF3538; Domain of unknown function (DUF3538)
  5. XM_006524118.4XP_006524181.1  large proline-rich protein BAG6 isoform X14

    See identical proteins and their annotated locations for XP_006524181.1

    Conserved Domains (3) summary
    PRK07764
    Location:10041195
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:58128
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:319433
    DUF3538; Domain of unknown function (DUF3538)
  6. XM_006524115.3XP_006524178.1  large proline-rich protein BAG6 isoform X7

    See identical proteins and their annotated locations for XP_006524178.1

    Conserved Domains (3) summary
    PRK07764
    Location:10041182
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:58128
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:319433
    DUF3538; Domain of unknown function (DUF3538)
  7. XM_017317432.2XP_017172921.1  large proline-rich protein BAG6 isoform X1

    Conserved Domains (3) summary
    PRK07764
    Location:10041224
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:58128
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:319433
    DUF3538; Domain of unknown function (DUF3538)
  8. XM_017317434.2XP_017172923.1  large proline-rich protein BAG6 isoform X8

    Conserved Domains (3) summary
    PRK07764
    Location:10041142
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:58128
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:319433
    DUF3538; Domain of unknown function (DUF3538)
  9. XM_036160539.1XP_036016432.1  large proline-rich protein BAG6 isoform X2

    Conserved Domains (3) summary
    PRK07764
    Location:10031223
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:58128
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:319433
    DUF3538; Domain of unknown function (DUF3538)
  10. XM_036160541.1XP_036016434.1  large proline-rich protein BAG6 isoform X6

    Conserved Domains (3) summary
    PRK07764
    Location:9681188
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:58128
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:319433
    DUF3538; Domain of unknown function (DUF3538)
  11. XM_030249721.1XP_030105581.1  large proline-rich protein BAG6 isoform X13

    Conserved Domains (3) summary
    PRK07764
    Location:9681106
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:58128
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:319433
    DUF3538; Domain of unknown function (DUF3538)
  12. XM_030249712.2XP_030105572.1  large proline-rich protein BAG6 isoform X3

    Conserved Domains (3) summary
    PRK07764
    Location:9851176
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:58128
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:301415
    DUF3538; Domain of unknown function (DUF3538)
  13. XM_030249715.2XP_030105575.1  large proline-rich protein BAG6 isoform X11

    UniProtKB/Swiss-Prot
    Q8SNA3
    Conserved Domains (3) summary
    PRK07764
    Location:9271118
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:278392
    DUF3538; Domain of unknown function (DUF3538)
  14. XM_006524112.4XP_006524175.1  large proline-rich protein BAG6 isoform X4

    Conserved Domains (3) summary
    PRK07764
    Location:9631154
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:278392
    DUF3538; Domain of unknown function (DUF3538)
  15. XM_006524113.4XP_006524176.1  large proline-rich protein BAG6 isoform X4

    See identical proteins and their annotated locations for XP_006524176.1

    Conserved Domains (3) summary
    PRK07764
    Location:9631154
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:278392
    DUF3538; Domain of unknown function (DUF3538)
  16. XM_006524114.3XP_006524177.1  large proline-rich protein BAG6 isoform X5

    Conserved Domains (3) summary
    PRK07764
    Location:9621153
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:278392
    DUF3538; Domain of unknown function (DUF3538)
  17. XM_030249711.1XP_030105571.1  large proline-rich protein BAG6 isoform X9

    Conserved Domains (3) summary
    PRK07764
    Location:9451136
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:260374
    DUF3538; Domain of unknown function (DUF3538)
  18. XM_036160542.1XP_036016435.1  large proline-rich protein BAG6 isoform X10

    Conserved Domains (3) summary
    PRK07764
    Location:9441135
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd01809
    Location:1787
    Ubl_BAG6; ubiquitin-like (Ubl) domain found in BCL2-associated athanogene 6 (BAG6) and similar proteins
    pfam12057
    Location:260374
    DUF3538; Domain of unknown function (DUF3538)