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Wbp2 WW domain binding protein 2 [ Mus musculus (house mouse) ]

Gene ID: 22378, updated on 19-Sep-2021

Summary

Official Symbol
Wbp2provided by MGI
Official Full Name
WW domain binding protein 2provided by MGI
Primary source
MGI:MGI:104709
See related
Ensembl:ENSMUSG00000034341
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Expression
Ubiquitous expression in adrenal adult (RPKM 171.5), duodenum adult (RPKM 125.2) and 28 other tissues See more
Orthologs
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Genomic context

See Wbp2 in Genome Data Viewer
Location:
11; 11 E2
Exon count:
8
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (115969397..115977821, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (116078571..116086995, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (115939887..115948278, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene unkempt family zinc finger Neighboring gene predicted gene, 38482 Neighboring gene unc-13 homolog D Neighboring gene tripartite motif-containing 47 Neighboring gene tripartite motif-containing 65

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
enables chromatin DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables chromatin DNA binding ISO
Inferred from Sequence Orthology
more info
 
enables estrogen receptor binding ISO
Inferred from Sequence Orthology
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables transcription coactivator activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables transcription coactivator activity ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in chromatin ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
WW domain-binding protein 2
Names
WBP-2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001347642.1NP_001334571.1  WW domain-binding protein 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AI837765, AI844895, AK043037, AL607108, DV657565
    Consensus CDS
    CCDS83934.1
    UniProtKB/Swiss-Prot
    P97765
    UniProtKB/TrEMBL
    Q544A1
    Related
    ENSMUSP00000102052.4, ENSMUST00000106444.4
  2. NM_001361446.1NP_001348375.1  WW domain-binding protein 2 isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks an exon and contains an alternate splice site in the 3' coding region, which results in a frameshift, compared to variant. 1. The encoded isoform (3) has a distinct C-terminus compared to isoform 1.
    Source sequence(s)
    AL607108
    Conserved Domains (1) summary
    cd13214
    Location:30131
    PH-GRAM_WBP2; WW binding protein 2 (WB2) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
  3. NM_016852.3NP_058548.1  WW domain-binding protein 2 isoform 1

    See identical proteins and their annotated locations for NP_058548.1

    Status: VALIDATED

    Source sequence(s)
    AL607108
    Consensus CDS
    CCDS25657.1
    UniProtKB/Swiss-Prot
    P97765
    UniProtKB/TrEMBL
    Q544A1
    Related
    ENSMUSP00000074204.7, ENSMUST00000074628.13
    Conserved Domains (1) summary
    cd13214
    Location:30131
    PH-GRAM_WBP2; WW binding protein 2 (WB2) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    115969397..115977821 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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