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Selenoo selenoprotein O [ Mus musculus (house mouse) ]

Gene ID: 223776, updated on 24-Dec-2022


Official Symbol
Selenooprovided by MGI
Official Full Name
selenoprotein Oprovided by MGI
Primary source
See related
Ensembl:ENSMUSG00000035757 AllianceGenome:MGI:1919007
Gene type
protein coding
RefSeq status
Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Selo; 1300018J18Rik
This gene encodes a selenoprotein that is localized to the mitochondria. It is the largest mammalian selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. The exact function of this selenoprotein is not known, but it is thought to have redox activity. [provided by RefSeq, Jan 2017]
Ubiquitous expression in adrenal adult (RPKM 58.1), liver adult (RPKM 45.3) and 28 other tissues See more
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Genomic context

See Selenoo in Genome Data Viewer
15; 15 E3
Exon count:
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (88973241..88984542)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (89089038..89100339)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene pannexin 2 Neighboring gene RIKEN cDNA 1810021B22 gene Neighboring gene TraB domain containing Neighboring gene tubulin, gamma complex associated protein 6 Neighboring gene histone deacetylase 10 Neighboring gene mitogen-activated protein kinase 12

Genomic regions, transcripts, and products


  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a



Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Pathways from PubChem


Products Interactant Other Gene Complex Source Pubs Description

General gene information



Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
enables nucleotidyltransferase activity IEA
Inferred from Electronic Annotation
more info
enables protein adenylyltransferase activity ISO
Inferred from Sequence Orthology
more info
enables transferase activity IEA
Inferred from Electronic Annotation
more info
Process Evidence Code Pubs
involved_in protein adenylylation ISO
Inferred from Sequence Orthology
more info
Component Evidence Code Pubs
located_in chromosome ISO
Inferred from Sequence Orthology
more info
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info

General protein information

Preferred Names
protein adenylyltransferase SelO, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_027905.3NP_082181.2  protein adenylyltransferase SelO, mitochondrial

    See identical proteins and their annotated locations for NP_082181.2

    Status: REVIEWED

    Source sequence(s)
    AK005048, AW060160, BE864360, BQ177186
    Consensus CDS
    Q80ZK3, Q9DBC0
    ENSMUSP00000081020.6, ENSMUST00000082439.6
    Conserved Domains (1) summary
    UPF0061; Uncharacterized ACR, YdiU/UPF0061 family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J


  1. NC_000081.7 Reference GRCm39 C57BL/6J

    GenBank, FASTA, Sequence Viewer (Graphics)