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Itgbl1 integrin, beta-like 1 [ Mus musculus (house mouse) ]

Gene ID: 223272, updated on 5-Jan-2022

Summary

Official Symbol
Itgbl1provided by MGI
Official Full Name
integrin, beta-like 1provided by MGI
Primary source
MGI:MGI:2443439
See related
Ensembl:ENSMUSG00000032925
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
B930011D01Rik
Summary
Predicted to enable integrin binding activity. Predicted to be involved in several processes, including cell adhesion mediated by integrin; cell-matrix adhesion; and integrin-mediated signaling pathway. Predicted to be located in extracellular region. Predicted to be part of integrin complex. Predicted to be active in cell surface and focal adhesion. Is expressed in axial skeleton; brain; heart ventricle; meninges; and vibrissa. Orthologous to human ITGBL1 (integrin subunit beta like 1). [provided by Alliance of Genome Resources, Nov 2021]
Expression
Broad expression in genital fat pad adult (RPKM 5.6), bladder adult (RPKM 5.3) and 17 other tissues See more
Orthologs
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Genomic context

See Itgbl1 in Genome Data Viewer
Location:
14; 14 E5
Exon count:
11
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (123897331..124215173)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (123659937..123978865)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (124059362..124373301)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene sodium leak channel, non-selective Neighboring gene pericentriolar material 1 pseudogene Neighboring gene predicted gene, 46490 Neighboring gene basic transcription factor 3, pseudogene 4 Neighboring gene RIKEN cDNA 1700024B18 gene Neighboring gene predicted gene, 25272 Neighboring gene predicted gene 15422 Neighboring gene fibroblast growth factor 14

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables integrin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in cell adhesion mediated by integrin IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in cell migration IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in cell-matrix adhesion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in integrin-mediated signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in cell surface IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 
is_active_in focal adhesion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of integrin complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
integrin beta-like protein 1
Names
with EGF-like repeat domains

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_145467.2NP_663442.2  integrin beta-like protein 1 precursor

    See identical proteins and their annotated locations for NP_663442.2

    Status: VALIDATED

    Source sequence(s)
    AK029068, BB676110, CJ154777
    Consensus CDS
    CCDS27354.1
    UniProtKB/Swiss-Prot
    Q8VDV0
    Related
    ENSMUSP00000059019.8, ENSMUST00000049681.14

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    123897331..124215173
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006518921.5XP_006518984.1  integrin beta-like protein 1 isoform X1

    Related
    ENSMUSP00000115455.2, ENSMUST00000132026.2
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