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Prap1 proline-rich acidic protein 1 [ Mus musculus (house mouse) ]

Gene ID: 22264, updated on 26-Sep-2022

Summary

Official Symbol
Prap1provided by MGI
Official Full Name
proline-rich acidic protein 1provided by MGI
Primary source
MGI:MGI:893573
See related
Ensembl:ENSMUSG00000025467 AllianceGenome:MGI:893573
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Upa
Summary
Enables triglyceride binding activity. Involved in cellular response to X-ray; negative regulation of apoptotic process; and positive regulation of lipid transport. Located in endoplasmic reticulum and extracellular region. Is expressed in several structures, including female reproductive system; intestine; and lower jaw. Orthologous to human PRAP1 (proline rich acidic protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in duodenum adult (RPKM 1621.5), small intestine adult (RPKM 1435.1) and 1 other tissue See more
Orthologs
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Genomic context

See Prap1 in Genome Data Viewer
Location:
7; 7 F4
Exon count:
5
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (139673309..139677116)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (140093396..140097203)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene VISTA enhancer mm1489 Neighboring gene calcyon neuron-specific vesicular protein Neighboring gene fucose mutarotase Neighboring gene enoyl Coenzyme A hydratase, short chain, 1, mitochondrial Neighboring gene polyamine oxidase (exo-N4-amino)

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

Homology

Gene Ontology Provided by MGI

General protein information

Preferred Names
proline-rich acidic protein 1
Names
pregnancy-specific uterine protein
uterine-specific proline-rich acidic protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009475.2NP_033501.2  proline-rich acidic protein 1 precursor

    See identical proteins and their annotated locations for NP_033501.2

    Status: VALIDATED

    Source sequence(s)
    AA060392, BC051092
    Consensus CDS
    CCDS21963.1
    UniProtKB/Swiss-Prot
    Q60874, Q80XD8
    Related
    ENSMUSP00000026540.9, ENSMUST00000026540.9
    Conserved Domains (1) summary
    pfam15314
    Location:100144
    PRAP; Proline-rich acidic protein 1, pregnancy-specific uterine

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    139673309..139677116
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)