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ADGRF2 adhesion G protein-coupled receptor F2 [ Homo sapiens (human) ]

Gene ID: 222611, updated on 23-Nov-2021

Summary

Official Symbol
ADGRF2provided by HGNC
Official Full Name
adhesion G protein-coupled receptor F2provided by HGNC
Primary source
HGNC:HGNC:18991
See related
Ensembl:ENSG00000164393
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PGR20; GPR111; hGPCR35
Expression
Biased expression in skin (RPKM 1.2), esophagus (RPKM 0.3) and 1 other tissue See more
Orthologs
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Genomic context

See ADGRF2 in Genome Data Viewer
Location:
6p12.3
Exon count:
12
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 6 NC_000006.12 (47656472..47697794)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (47624208..47665530)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene CD2 associated protein Neighboring gene ribosomal protein S12 pseudogene 14 Neighboring gene DnaJ heat shock protein family (Hsp40) member C17 pseudogene Neighboring gene adhesion G protein-coupled receptor F4 Neighboring gene RN7SK pseudogene 116 Neighboring gene ribosomal protein L27a pseudogene 7

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Potential readthrough

Included gene: ADGRF4

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in cell surface receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
adhesion G-protein coupled receptor F2
Names
G protein-coupled receptor 111
probable G-protein coupled receptor 111

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001368115.2NP_001355044.1  adhesion G-protein coupled receptor F2 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AL356421
    Related
    ENSP00000296862.1, ENST00000296862.5
  2. NM_001394650.1NP_001381579.1  adhesion G-protein coupled receptor F2 isoform 3 precursor

    Status: VALIDATED

    Source sequence(s)
    AL356421
    Conserved Domains (2) summary
    cd15994
    Location:375621
    7tmB2_GPR111_115; orphan adhesion receptors GPR111 and GPR115, member of the class B2 family of seven-transmembrane G protein-coupled receptors
    cl02559
    Location:323370
    GPS; GPCR proteolysis site, GPS, motif
  3. NM_153839.7NP_722581.4  adhesion G-protein coupled receptor F2 isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    AL356421
    UniProtKB/Swiss-Prot
    Q8IZF7
    Related
    ENSP00000425269.1, ENST00000467205.6
    Conserved Domains (2) summary
    pfam01825
    Location:325367
    GPS; GPCR proteolysis site, GPS, motif
    cl21561
    Location:378625
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p13 Primary Assembly

    Range
    47656472..47697794
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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