U.S. flag

An official website of the United States government


Send to:

Choose Destination

SLC35F1 solute carrier family 35 member F1 [ Homo sapiens (human) ]

Gene ID: 222553, updated on 3-Dec-2023


Official Symbol
SLC35F1provided by HGNC
Official Full Name
solute carrier family 35 member F1provided by HGNC
Primary source
See related
Ensembl:ENSG00000196376 MIM:620349; AllianceGenome:HGNC:21483
Gene type
protein coding
RefSeq status
Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C6orf169; dJ230I3.1
Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Annotation information
Note: This gene has been reviewed for its involvement in coronavirus biology, and is locus in the vicinity of disease-associated variant(s).
Biased expression in brain (RPKM 17.3), heart (RPKM 1.2) and 1 other tissue See more
Try the new Gene table
Try the new Transcript table

Genomic context

See SLC35F1 in Genome Data Viewer
Exon count:
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (117907264..118317671)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (119091523..119502777)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (118228427..118638834)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene MPRA-validated peak6055 silencer Neighboring gene MPRA-validated peak6057 silencer Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25012 Neighboring gene NUS1 dehydrodolichyl diphosphate synthase subunit Neighboring gene uncharacterized LOC124901480 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr6:118276469-118277668 Neighboring gene ribosomal protein L29 pseudogene 4 Neighboring gene uncharacterized LOC105377967 Neighboring gene uncharacterized LOC107986523 Neighboring gene ReSE screen-validated silencer GRCh37_chr6:118509313-118509526 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17500 Neighboring gene uncharacterized LOC124901387 Neighboring gene uncharacterized LOC105377971 Neighboring gene ATP-dependent RNA helicase DDX24-like Neighboring gene centrosomal protein 85 like

Genomic regions, transcripts, and products


  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018


GeneRIFs: Gene References Into Functions

What's a GeneRIF?


EBI GWAS Catalog

Common genetic variation near the phospholamban gene is associated with cardiac repolarisation: meta-analysis of three genome-wide association studies.
EBI GWAS Catalog
Common variants at ten loci influence QT interval duration in the QTGEN Study.
EBI GWAS Catalog
Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization.
EBI GWAS Catalog
Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data.
EBI GWAS Catalog
Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans.
EBI GWAS Catalog
Genome-wide association analysis identifies multiple loci related to resting heart rate.
EBI GWAS Catalog
Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.
EBI GWAS Catalog


Products Interactant Other Gene Complex Source Pubs Description

General gene information


Clone Names

  • FLJ13018

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
Process Evidence Code Pubs
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
Component Evidence Code Pubs
located_in synaptic vesicle membrane IDA
Inferred from Direct Assay
more info

General protein information

Preferred Names
solute carrier family 35 member F1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001029858.4NP_001025029.2  solute carrier family 35 member F1

    See identical proteins and their annotated locations for NP_001025029.2

    Status: VALIDATED

    Source sequence(s)
    AL133379, AL136478, AL449196, Z95326
    Consensus CDS
    B4DJ02, E1P564, Q1RMG1, Q4G0U9, Q4G167, Q5T1Q4, Q6N007
    ENSP00000353557.4, ENST00000360388.9
    Conserved Domains (1) summary
    SLC35F; Solute carrier family 35
  2. NM_001415931.1NP_001402860.1  solute carrier family 35 member F1

    Status: VALIDATED

    Source sequence(s)
    AL133379, AL136478, AL449196, Z95326
    B4DJ02, E1P564, Q1RMG1, Q4G0U9, Q4G167, Q5T1Q4, Q6N007

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly


  1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0


  1. NC_060930.1 Alternate T2T-CHM13v2.0

    GenBank, FASTA, Sequence Viewer (Graphics)