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Uncx UNC homeobox [ Mus musculus (house mouse) ]

Gene ID: 22255, updated on 8-Dec-2018

Summary

Official Symbol
Uncxprovided by MGI
Official Full Name
UNC homeoboxprovided by MGI
Primary source
MGI:MGI:108013
See related
Ensembl:ENSMUSG00000029546
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Chx4; Uncx4.1
Expression
Biased expression in CNS E11.5 (RPKM 16.6), whole brain E14.5 (RPKM 10.7) and 3 other tissues See more
Orthologs

Genomic context

See Uncx in Genome Data Viewer
Location:
5 G2; 5 78.75 cM
Exon count:
4
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 5 NC_000071.6 (139543898..139548179)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (140019852..140024133)

Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene zinc finger, AN1-type domain 2A Neighboring gene RIKEN cDNA 4930500L23 gene Neighboring gene predicted gene, 46926 Neighboring gene MICAL-like 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
cartilage condensation IMP
Inferred from Mutant Phenotype
more info
PubMed 
cell differentiation IEA
Inferred from Electronic Annotation
more info
 
common myeloid progenitor cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
dorsal spinal cord development IMP
Inferred from Mutant Phenotype
more info
PubMed 
multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
nervous system development IEA
Inferred from Electronic Annotation
more info
 
olfactory bulb interneuron differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
pattern specification process IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of gene expression IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
homeobox protein unc-4 homolog
Names
Unc4.1 homeobox
homeobox protein Uncx4.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_013702.3NP_038730.1  homeobox protein unc-4 homolog

    See identical proteins and their annotated locations for NP_038730.1

    Status: VALIDATED

    Source sequence(s)
    AJ001116, AK082472, AV120135, BC051973
    Consensus CDS
    CCDS19813.1
    UniProtKB/Swiss-Prot
    O08934
    Related
    ENSMUSP00000134067.2, ENSMUST00000172997.2
    Conserved Domains (1) summary
    pfam00046
    Location:112165
    Homeobox; Homeobox domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000071.6 Reference GRCm38.p4 C57BL/6J

    Range
    139543898..139548179
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006504668.3XP_006504731.1  homeobox protein unc-4 homolog isoform X1

    Conserved Domains (1) summary
    PRK12270
    Location:243337
    kgd; alpha-ketoglutarate decarboxylase; Reviewed
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