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Ubp1 upstream binding protein 1 [ Mus musculus (house mouse) ]

Gene ID: 22221, updated on 26-Sep-2022

Summary

Official Symbol
Ubp1provided by MGI
Official Full Name
upstream binding protein 1provided by MGI
Primary source
MGI:MGI:104889
See related
Ensembl:ENSMUSG00000009741 AllianceGenome:MGI:104889
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Cp2b; NF2d9; LBP-1a; LBP-1b
Summary
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within angiogenesis. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including aorta; early conceptus; genitourinary system; gut gland; and limb. Orthologous to human UBP1 (upstream binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E14 (RPKM 37.3), limb E14.5 (RPKM 35.1) and 28 other tissues See more
Orthologs
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Genomic context

See Ubp1 in Genome Data Viewer
Location:
9; 9 F3
Exon count:
19
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (113760002..113807095)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (113930939..113978027)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene CLIP associating protein 2 Neighboring gene predicted gene, 25059 Neighboring gene predicted gene, 39439 Neighboring gene F-box and leucine-rich repeat protein 2 Neighboring gene predicted gene, 36035 Neighboring gene predicted gene, 36883

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (3)  1 citation
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Component Evidence Code Pubs
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
upstream-binding protein 1
Names
nuclear factor 2d9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001083319.2NP_001076788.1  upstream-binding protein 1 isoform a

    See identical proteins and their annotated locations for NP_001076788.1

    Status: VALIDATED

    Source sequence(s)
    AC107803, CT025531
    Consensus CDS
    CCDS40788.1
    UniProtKB/Swiss-Prot
    Q811S7, Q8C514
    UniProtKB/TrEMBL
    A0A8C6ICQ6
    Related
    ENSMUSP00000081946.6, ENSMUST00000084885.12
    Conserved Domains (2) summary
    cd09588
    Location:369435
    SAM_LBP1; SAM domain of LBP1 (UBP1) transcription factors
    pfam04516
    Location:50254
    CP2; CP2 transcription factor
  2. NM_001372507.1NP_001359436.1  upstream-binding protein 1 isoform a

    Status: VALIDATED

    Source sequence(s)
    AC107803, CT025531
    UniProtKB/Swiss-Prot
    Q8C514
    UniProtKB/TrEMBL
    A0A8C6ICQ6
    Conserved Domains (2) summary
    cd09588
    Location:369435
    SAM_LBP1; SAM domain of LBP1 (UBP1) transcription factors
    pfam04516
    Location:50254
    CP2; CP2 transcription factor
  3. NM_001372508.1NP_001359437.1  upstream-binding protein 1 isoform a

    Status: VALIDATED

    Source sequence(s)
    AC107803, CT025531
    UniProtKB/Swiss-Prot
    Q8C514
    UniProtKB/TrEMBL
    A0A8C6ICQ6
    Conserved Domains (2) summary
    cd09588
    Location:369435
    SAM_LBP1; SAM domain of LBP1 (UBP1) transcription factors
    pfam04516
    Location:50254
    CP2; CP2 transcription factor
  4. NM_001372510.1NP_001359439.1  upstream-binding protein 1 isoform a

    Status: VALIDATED

    Source sequence(s)
    AC107803, CT025531
    UniProtKB/Swiss-Prot
    Q8C514
    UniProtKB/TrEMBL
    A0A8C6ICQ6
    Related
    ENSMUSP00000150023.2, ENSMUST00000216558.2
    Conserved Domains (2) summary
    cd09588
    Location:369435
    SAM_LBP1; SAM domain of LBP1 (UBP1) transcription factors
    pfam04516
    Location:50254
    CP2; CP2 transcription factor
  5. NM_001372511.1NP_001359440.1  upstream-binding protein 1 isoform b

    Status: VALIDATED

    Source sequence(s)
    AC107803, CT025531
    Related
    ENSMUSP00000149908.2, ENSMUST00000214095.2
    Conserved Domains (2) summary
    cd09588
    Location:333399
    SAM_LBP1; SAM domain of LBP1 (UBP1) transcription factors
    pfam04516
    Location:50254
    CP2; CP2 transcription factor
  6. NM_001372512.1NP_001359441.1  upstream-binding protein 1 isoform b

    Status: VALIDATED

    Source sequence(s)
    AC107803, CT025531
    Conserved Domains (2) summary
    cd09588
    Location:333399
    SAM_LBP1; SAM domain of LBP1 (UBP1) transcription factors
    pfam04516
    Location:50254
    CP2; CP2 transcription factor
  7. NM_001372514.1NP_001359443.1  upstream-binding protein 1 isoform b

    Status: VALIDATED

    Source sequence(s)
    AC107803, CT025531
    Conserved Domains (2) summary
    cd09588
    Location:333399
    SAM_LBP1; SAM domain of LBP1 (UBP1) transcription factors
    pfam04516
    Location:50254
    CP2; CP2 transcription factor
  8. NM_013699.3NP_038727.1  upstream-binding protein 1 isoform b

    See identical proteins and their annotated locations for NP_038727.1

    Status: VALIDATED

    Source sequence(s)
    AC107803, CT025531
    Consensus CDS
    CCDS40789.1
    UniProtKB/Swiss-Prot
    Q811S7
    Related
    ENSMUSP00000009885.8, ENSMUST00000009885.14
    Conserved Domains (2) summary
    cd09588
    Location:333399
    SAM_LBP1; SAM domain of LBP1 (UBP1) transcription factors
    pfam04516
    Location:50254
    CP2; CP2 transcription factor

RNA

  1. NR_164181.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC107803, CT025531

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    113760002..113807095
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036154842.1XP_036010735.1  upstream-binding protein 1 isoform X4

    Conserved Domains (2) summary
    cd09588
    Location:333399
    SAM_LBP1; SAM domain of LBP1 (UBP1) transcription factors
    pfam04516
    Location:50254
    CP2; CP2 transcription factor
  2. XM_006512055.3XP_006512118.1  upstream-binding protein 1 isoform X3

    See identical proteins and their annotated locations for XP_006512118.1

    Conserved Domains (2) summary
    cd09588
    Location:369435
    SAM_LBP1; SAM domain of LBP1 (UBP1) transcription factors
    pfam04516
    Location:50254
    CP2; CP2 transcription factor
  3. XM_006512050.5XP_006512113.3  upstream-binding protein 1 isoform X1

    Conserved Domains (2) summary
    cd09588
    Location:458524
    SAM_LBP1; SAM domain of LBP1 (UBP1) transcription factors
    pfam04516
    Location:139343
    CP2; CP2 transcription factor
  4. XM_006512052.5XP_006512115.3  upstream-binding protein 1 isoform X2

    Conserved Domains (2) summary
    cd09588
    Location:422488
    SAM_LBP1; SAM domain of LBP1 (UBP1) transcription factors
    pfam04516
    Location:139343
    CP2; CP2 transcription factor
  5. XM_030244246.1XP_030100106.1  upstream-binding protein 1 isoform X7

    Related
    ENSMUST00000216891.2
    Conserved Domains (2) summary
    cd09588
    Location:181247
    SAM_LBP1; SAM domain of LBP1 (UBP1) transcription factors
    pfam04516
    Location:2102
    CP2; CP2 transcription factor
  6. XM_006512058.4XP_006512121.1  upstream-binding protein 1 isoform X5

    Conserved Domains (3) summary
    cd09588
    Location:217283
    SAM_LBP1; SAM domain of LBP1 (UBP1) transcription factors
    pfam04516
    Location:2102
    CP2; CP2 transcription factor
    pfam17061
    Location:135197
    PARM
  7. XM_030244245.1XP_030100105.1  upstream-binding protein 1 isoform X6

    Conserved Domains (3) summary
    cd09588
    Location:217283
    SAM_LBP1; SAM domain of LBP1 (UBP1) transcription factors
    pfam04516
    Location:2102
    CP2; CP2 transcription factor
    pfam17061
    Location:135197
    PARM

RNA

  1. XR_001778854.3 RNA Sequence

  2. XR_001778853.3 RNA Sequence

  3. XR_001778856.3 RNA Sequence

  4. XR_379864.5 RNA Sequence

  5. XR_001778855.3 RNA Sequence

  6. XR_001778857.3 RNA Sequence

  7. XR_001778852.3 RNA Sequence

  8. XR_001778858.3 RNA Sequence

  9. XR_004935386.1 RNA Sequence

  10. XR_004935387.1 RNA Sequence