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CCZ1B CCZ1 homolog B, vacuolar protein trafficking and biogenesis associated [ Homo sapiens (human) ]

Gene ID: 221960, updated on 23-Nov-2021

Summary

Official Symbol
CCZ1Bprovided by HGNC
Official Full Name
CCZ1 homolog B, vacuolar protein trafficking and biogenesis associatedprovided by HGNC
Primary source
HGNC:HGNC:21717
See related
Ensembl:ENSG00000146574
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CCZ1; C7orf28A; C7orf28B; H_NH0577018.2
Expression
Ubiquitous expression in adrenal (RPKM 39.8), urinary bladder (RPKM 33.4) and 25 other tissues See more
Orthologs
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Genomic context

See CCZ1B in Genome Data Viewer
Location:
7p22.1
Exon count:
15
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (6798937..6826275, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (6838568..6865906, complement)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene PMS2 C-terminal like pseudogene Neighboring gene radial spoke head 10 homolog B2 Neighboring gene uncharacterized LOC107986696 Neighboring gene Sharpr-MPRA regulatory region 9278 Neighboring gene olfactory receptor family 7 subfamily E member 39 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

HIV-1 interactions

Protein interactions

Protein Gene Interaction Pubs
Vif vif HIV-1 Vif downregulates the expression of CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (CCZ1B) in Vif-expression T cells PubMed

Go to the HIV-1, Human Interaction Database

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ60592, MGC19819, DKFZp586I1023

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
part_of Mon1-Ccz1 complex IEA
Inferred from Electronic Annotation
more info
 
is_active_in intracellular membrane-bounded organelle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in intracellular membrane-bounded organelle IDA
Inferred from Direct Assay
more info
 
located_in lysosomal membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
vacuolar fusion protein CCZ1 homolog B
Names
CCZ1 homolog, vacuolar protein trafficking and biogenesis associated B
CCZ1 vacuolar protein trafficking and biogenesis associated B
CCZ1 vacuolar protein trafficking and biogenesis associated homolog B
H_DJ1163J12.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_198097.5NP_932765.1  vacuolar fusion protein CCZ1 homolog B

    See identical proteins and their annotated locations for NP_932765.1

    Status: VALIDATED

    Source sequence(s)
    AC079882
    Consensus CDS
    CCDS5354.1
    UniProtKB/Swiss-Prot
    P86790, P86791
    Related
    ENSP00000314544.8, ENST00000316731.13
    Conserved Domains (1) summary
    pfam08217
    Location:27479
    DUF1712; Fungal domain of unknown function (DUF1712)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

    Range
    6798937..6826275 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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