Format

Send to:

Choose Destination

HOXA11-AS HOXA11 antisense RNA [ Homo sapiens (human) ]

Gene ID: 221883, updated on 2-Jun-2020

Summary

Official Symbol
HOXA11-ASprovided by HGNC
Official Full Name
HOXA11 antisense RNAprovided by HGNC
Primary source
HGNC:HGNC:24957
See related
Ensembl:ENSG00000240990 MIM:607530
Gene type
ncRNA
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HOXA11S; HOXA-AS5; HOXA11AS; HOXA11-AS1; NCRNA00076
Summary
This gene produces a long non-coding RNA in antisense to transcription of the homeobox A11 gene. This transcript may associate with chromatin factors such as Polycomb repressive complex and act as a sponge for microRNAs, thereby participating in the regulation of expression of target genes. High levels of this transcript may be associated with tumor progression. [provided by RefSeq, Dec 2017]
Expression
Biased expression in prostate (RPKM 18.6), endometrium (RPKM 8.7) and 3 other tissues See more
Orthologs

Genomic context

See HOXA11-AS in Genome Data Viewer
Location:
7p15.2
Exon count:
2
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (27185408..27189293)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (27225027..27228912)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene HOXA10-HOXA9 readthrough Neighboring gene HOXA10 antisense RNA Neighboring gene homeobox A10 Neighboring gene NUP98-HOXA11 recombination region Neighboring gene homeobox A11 Neighboring gene homeobox A13 Neighboring gene NUP98-HOXA13 recombination region Neighboring gene HOXA distal transcript antisense RNA

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Markers

Homology

Other Names

  • HOXA cluster antisense RNA 5 (non-protein coding)
  • HOXA11 antisense RNA 1 (non-protein coding)
  • homeo box A11, opposite strand transcript
  • homeobox A11 antisense

Gene Ontology Provided by GOA

Process Evidence Code Pubs
negative regulation of gene expression IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_002795.2 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    BC025338, BI753022, DA421792
    Related
    ENST00000522674.1

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

    Range
    27185408..27189293
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center