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FAM162B family with sequence similarity 162 member B [ Homo sapiens (human) ]

Gene ID: 221303, updated on 13-May-2022

Summary

Official Symbol
FAM162Bprovided by HGNC
Official Full Name
family with sequence similarity 162 member Bprovided by HGNC
Primary source
HGNC:HGNC:21549
See related
Ensembl:ENSG00000183807 AllianceGenome:HGNC:21549
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C6orf189; bA86F4.2
Summary
Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in placenta (RPKM 28.7), lung (RPKM 9.9) and 9 other tissues See more
Orthologs
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Genomic context

See FAM162B in Genome Data Viewer
Location:
6q22.1
Exon count:
4
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (116752197..116765719, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (117935892..117949422, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (117073360..117086882, complement)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene zinc finger containing ubiquitin peptidase 1 Neighboring gene karyopherin subunit alpha 5 Neighboring gene U2 spliceosomal RNA Neighboring gene uncharacterized LOC105377963 Neighboring gene G protein-coupled receptor class C group 6 member A

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

EBI GWAS Catalog

Description
A genome-wide association study identifies a locus on chromosome 14q21 as a predictor of leukocyte telomere length and as a marker of susceptibility for bladder cancer.
EBI GWAS Catalog

General gene information

Markers

Potential readthrough

Included gene: ZUP1

Homology

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001085480.3NP_001078949.1  protein FAM162B

    See identical proteins and their annotated locations for NP_001078949.1

    Status: VALIDATED

    Source sequence(s)
    BC038997, H71557
    Consensus CDS
    CCDS43497.1
    UniProtKB/Swiss-Prot
    Q5T6X4
    Related
    ENSP00000357545.4, ENST00000368557.6
    Conserved Domains (1) summary
    pfam06388
    Location:35152
    DUF1075; Protein of unknown function (DUF1075)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

    Range
    116752197..116765719 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060930.1 Alternate T2T-CHM13v2.0

    Range
    117935892..117949422 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)