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SLC16A9 solute carrier family 16 member 9 [ Homo sapiens (human) ]

Gene ID: 220963, updated on 11-Jun-2021

Summary

Official Symbol
SLC16A9provided by HGNC
Official Full Name
solute carrier family 16 member 9provided by HGNC
Primary source
HGNC:HGNC:23520
See related
Ensembl:ENSG00000165449 MIM:614242
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MCT9; C10orf36
Expression
Biased expression in adrenal (RPKM 82.1), kidney (RPKM 62.2) and 9 other tissues See more
Orthologs
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Genomic context

See SLC16A9 in Genome Data Viewer
Location:
10q21.2
Exon count:
10
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 10 NC_000010.11 (59650764..59710079, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (61410522..61469837, complement)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105378318 Neighboring gene uncharacterized LOC105378319 Neighboring gene myoregulin Neighboring gene coiled-coil domain containing 6

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
An atlas of genetic influences on human blood metabolites.
GeneReviews: Not available
Gene-alcohol interactions identify several novel blood pressure loci including a promising locus near SLC16A9.
GeneReviews: Not available
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.
GeneReviews: Not available
Human metabolic individuality in biomedical and pharmaceutical research.
GeneReviews: Not available
Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations.
GeneReviews: Not available

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ43803

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables monocarboxylic acid transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables symporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in monocarboxylic acid transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in urate metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
is_active_in integral component of membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
monocarboxylate transporter 9
Names
MCT 9
monocarboxylic acid transporter 9
solute carrier family 16 (monocarboxylic acid transporters), member 9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001323977.1NP_001310906.1  monocarboxylate transporter 9 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3), as well as variants 4, 5, and 6, encodes isoform b.
    Source sequence(s)
    AC026391, DA759951
  2. NM_001323978.2NP_001310907.1  monocarboxylate transporter 9 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4), as well as variants 3, 5, and 6, encodes isoform b.
    Source sequence(s)
    AC022027, AC026391
  3. NM_001323979.2NP_001310908.1  monocarboxylate transporter 9 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5), as well as variants 3, 4, and 6, encodes isoform b.
    Source sequence(s)
    AC022027, AC026391
  4. NM_001323980.2NP_001310909.1  monocarboxylate transporter 9 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6), as well as variants 3, 4, and 5, encodes isoform b.
    Source sequence(s)
    AC022027, AC026391
  5. NM_001323981.2NP_001310910.1  monocarboxylate transporter 9 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2), as well as variant 1, encodes isoform a.
    Source sequence(s)
    AC022027, AC026391
    Consensus CDS
    CCDS7256.1
    UniProtKB/Swiss-Prot
    Q7RTY1
    Conserved Domains (1) summary
    cl26868
    Location:7481
    2A0111; oxalate/formate antiporter family transporter
  6. NM_194298.3NP_919274.1  monocarboxylate transporter 9 isoform a

    See identical proteins and their annotated locations for NP_919274.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1), as well as variant 2, encodes isoform a.
    Source sequence(s)
    AK125791, BC126238, BX092606, CX784319, DA229807
    Consensus CDS
    CCDS7256.1
    UniProtKB/Swiss-Prot
    Q7RTY1
    Related
    ENSP00000378757.3, ENST00000395348.8
    Conserved Domains (1) summary
    cl26868
    Location:7481
    2A0111; oxalate/formate antiporter family transporter

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p13 Primary Assembly

    Range
    59650764..59710079 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017015883.1XP_016871372.1  monocarboxylate transporter 9 isoform X1

  2. XM_017015884.2XP_016871373.1  monocarboxylate transporter 9 isoform X2

    UniProtKB/Swiss-Prot
    Q7RTY1
    Conserved Domains (1) summary
    cl26868
    Location:7481
    2A0111; oxalate/formate antiporter family transporter
  3. XM_024447878.1XP_024303646.1  monocarboxylate transporter 9 isoform X2

    Related
    ENSP00000378756.1, ENST00000395347.1
    Conserved Domains (1) summary
    cl26868
    Location:7481
    2A0111; oxalate/formate antiporter family transporter
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