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ZEB1-AS1 ZEB1 antisense RNA 1 [ Homo sapiens (human) ]

Gene ID: 220930, updated on 1-Jun-2020

Summary

Official Symbol
ZEB1-AS1provided by HGNC
Official Full Name
ZEB1 antisense RNA 1provided by HGNC
Primary source
HGNC:HGNC:42354
See related
Ensembl:ENSG00000237036 MIM:616915
Gene type
ncRNA
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This locus produces long non-coding RNA that is transcribed from a shared bi-directional promoter with zinc finger E-box binding homeobox 1 (ZEB1). This transcript binds lysine methyltransferase 2A and promotes histone modifications that are thought to promote expression of ZEB1. Expression of this gene is correlated with tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2017]
Expression
Ubiquitous expression in endometrium (RPKM 3.5), ovary (RPKM 3.4) and 25 other tissues See more

Genomic context

See ZEB1-AS1 in Genome Data Viewer
Location:
10p11.22
Exon count:
6
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 10 NC_000010.11 (31307717..31320447, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (31605457..31608024, complement)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105376481 Neighboring gene uncharacterized LOC105376483 Neighboring gene long intergenic non-protein coding RNA 2664 Neighboring gene RNA, 5S ribosomal pseudogene 309 Neighboring gene putative UPF0607 protein FLJ37424 Neighboring gene zinc finger E-box binding homeobox 1 Neighboring gene serine palmitoyltransferase long chain base subunit 1 pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_024284.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AK026657, BX446976, DB121883, DB127940
    Related
    ENST00000659795.1
  2. NR_148975.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AK026657, DA998606
  3. NR_148976.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AI808408, AK026657, AW005512
  4. NR_148977.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AK026657, DB121883, DC351677
    Related
    ENST00000607166.1
  5. NR_148978.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AI149234, BM703926, DB121883
    Related
    ENST00000450834.2
  6. NR_148979.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AL117340

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p13 Primary Assembly

    Range
    31307717..31320447 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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