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Tob1 transducer of ErbB-2.1 [ Mus musculus (house mouse) ]

Gene ID: 22057, updated on 3-Jun-2018
Official Symbol
Tob1provided by MGI
Official Full Name
transducer of ErbB-2.1provided by MGI
Primary source
MGI:MGI:1349721
See related
Ensembl:ENSMUSG00000037573 Vega:OTTMUSG00000001711
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Tob; Trob
Expression
Broad expression in adrenal adult (RPKM 238.6), duodenum adult (RPKM 166.5) and 18 other tissues See more
Orthologs
See Tob1 in Genome Data Viewer
Location:
11; 11 D
Exon count:
2
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 11 NC_000077.6 (94211454..94215495)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (94072768..94076809)

Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene sperm associated antigen 9 Neighboring gene predicted gene, 38951 Neighboring gene RIKEN cDNA B230206L02 gene Neighboring gene predicted gene, 35338 Neighboring gene WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 Neighboring gene predicted gene, 38953

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Diurnally Regulated Genes with Circadian Orthologs, organism-specific biosystem (from WikiPathways)
    Diurnally Regulated Genes with Circadian Orthologs, organism-specific biosystemMouse genes regulated in the diurnal (inferred from human) and compared with mouse genes that display circadian regulation in mouse heart and liver (Panda 2002, Storch 2002), and SCN (Panda 2002). Th...
  • Exercise-induced Circadian Regulation, organism-specific biosystem (from WikiPathways)
    Exercise-induced Circadian Regulation, organism-specific biosystem
    Exercise-induced Circadian Regulation
  • RNA degradation, organism-specific biosystem (from KEGG)
    RNA degradation, organism-specific biosystemThe correct processing, quality control and turnover of cellular RNA molecules are critical to many aspects in the expression of genetic information. In eukaryotes, two major pathways of mRNA decay e...
  • RNA degradation, conserved biosystem (from KEGG)
    RNA degradation, conserved biosystemThe correct processing, quality control and turnover of cellular RNA molecules are critical to many aspects in the expression of genetic information. In eukaryotes, two major pathways of mRNA decay e...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
SMAD binding IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
receptor tyrosine kinase binding ISO
Inferred from Sequence Orthology
more info
 
transcription corepressor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transcription corepressor activity IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
CCR4-NOT complex ISO
Inferred from Sequence Orthology
more info
 
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Preferred Names
protein Tob1
Names
transducer of erbB2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009427.2NP_033453.2  protein Tob1

    See identical proteins and their annotated locations for NP_033453.2

    Status: VALIDATED

    Source sequence(s)
    AL645846, CF748516
    Consensus CDS
    CCDS25250.1
    UniProtKB/Swiss-Prot
    Q61471
    Related
    ENSMUSP00000036039.5, OTTMUSP00000001617, ENSMUST00000041589.5, OTTMUST00000003376
    Conserved Domains (1) summary
    smart00099
    Location:1106
    btg1; tob/btg1 family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000077.6 Reference GRCm38.p4 C57BL/6J

    Range
    94211454..94215495
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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