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OOSP2 oocyte secreted protein 2 [ Homo sapiens (human) ]

Gene ID: 219990, updated on 9-Jun-2025
Official Symbol
OOSP2provided by HGNC
Official Full Name
oocyte secreted protein 2provided by HGNC
Primary source
HGNC:HGNC:26699
See related
Ensembl:ENSG00000149507 MIM:620263; AllianceGenome:HGNC:26699
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OOSP2A; PLAC1L; TMEM122
Summary
Involved in oocyte maturation. Located in cytoplasm. [provided by Alliance of Genome Resources, Jun 2025]
Expression
Restricted expression toward testis (RPKM 16.1) See more
Orthologs
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See OOSP2 in Genome Data Viewer
Location:
11q12.1
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (60040409..60048044)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (59991696..59999331)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (59807882..59815517)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene oocyte secreted protein family member 4A Neighboring gene oocyte secreted protein family member 4B Neighboring gene membrane spanning 4-domains A3 Neighboring gene tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta pseudogene 9

  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018
Products Interactant Other Gene Complex Source Pubs Description

Clone Names

  • FLJ36198

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in oocyte maturation IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
oocyte-secreted protein 2
Names
placenta-specific 1-like protein
testicular tissue protein Li 142
transmembrane protein 122

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_173801.5NP_776162.2  oocyte-secreted protein 2 precursor

    See identical proteins and their annotated locations for NP_776162.2

    Status: VALIDATED

    Source sequence(s)
    BC036256, BC048121
    Consensus CDS
    CCDS7979.1
    UniProtKB/Swiss-Prot
    E9PJA4, Q86WS3, Q8N9U6
    UniProtKB/TrEMBL
    A0A140VJR6
    Related
    ENSP00000278855.2, ENST00000278855.7

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    60040409..60048044
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_019805498.1 Reference GRCh38.p14 PATCHES

    Range
    130064..137702
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    59991696..59999331
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)