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GLYATL2 glycine-N-acyltransferase like 2 [ Homo sapiens (human) ]

Gene ID: 219970, updated on 5-Jan-2022

Summary

Official Symbol
GLYATL2provided by HGNC
Official Full Name
glycine-N-acyltransferase like 2provided by HGNC
Primary source
HGNC:HGNC:24178
See related
Ensembl:ENSG00000156689 MIM:614762
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
GATF-B; BXMAS2-10
Summary
Enables glycine N-acyltransferase activity. Involved in long-chain fatty acid catabolic process; medium-chain fatty acid catabolic process; and monounsaturated fatty acid catabolic process. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Nov 2021]
Expression
Biased expression in gall bladder (RPKM 3.1), salivary gland (RPKM 1.2) and 5 other tissues See more
Orthologs
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Genomic context

See GLYATL2 in Genome Data Viewer
Location:
11q12.1
Exon count:
9
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (58834065..58905840, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (58601538..58612177, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 12556 Neighboring gene translation machinery associated 16 homolog pseudogene 1 Neighboring gene glycine-N-acyltransferase like 1 pseudogene 2 Neighboring gene glycine-N-acyltransferase like 1 Neighboring gene uncharacterized LOC283194 Neighboring gene protein kinase cAMP-dependent type II regulatory subunit beta pseudogene Neighboring gene glycine-N-acyltransferase like 1 pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General protein information

Preferred Names
glycine N-acyltransferase-like protein 2
Names
acyl-CoA:glycine N-acyltransferase-like protein 2
glycine acyltransferase family-B
NP_659453.3
XP_011543111.1
XP_016872826.1
XP_016872827.1
XP_024304162.1
XP_024304163.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_145016.4NP_659453.3  glycine N-acyltransferase-like protein 2

    See identical proteins and their annotated locations for NP_659453.3

    Status: VALIDATED

    Source sequence(s)
    AP001652, AW264415, BC021682
    Consensus CDS
    CCDS41649.1
    UniProtKB/Swiss-Prot
    Q8WU03
    UniProtKB/TrEMBL
    A0A024R4Z5
    Related
    ENSP00000287275.1, ENST00000287275.6
    Conserved Domains (2) summary
    pfam08444
    Location:202290
    Gly_acyl_tr_C; Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region
    pfam06021
    Location:10199
    Gly_acyl_tr_N; Aralkyl acyl-CoA:amino acid N-acyltransferase

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    58834065..58905840 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024448395.1XP_024304163.1  glycine N-acyltransferase-like protein 2 isoform X1

    Conserved Domains (2) summary
    pfam08444
    Location:202290
    Gly_acyl_tr_C; Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region
    pfam06021
    Location:10199
    Gly_acyl_tr_N; Aralkyl acyl-CoA:amino acid N-acyltransferase
  2. XM_024448394.1XP_024304162.1  glycine N-acyltransferase-like protein 2 isoform X1

    Conserved Domains (2) summary
    pfam08444
    Location:202290
    Gly_acyl_tr_C; Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region
    pfam06021
    Location:10199
    Gly_acyl_tr_N; Aralkyl acyl-CoA:amino acid N-acyltransferase
  3. XM_017017337.2XP_016872826.1  glycine N-acyltransferase-like protein 2 isoform X1

    UniProtKB/Swiss-Prot
    Q8WU03
    UniProtKB/TrEMBL
    A0A024R4Z5
    Conserved Domains (2) summary
    pfam08444
    Location:202290
    Gly_acyl_tr_C; Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region
    pfam06021
    Location:10199
    Gly_acyl_tr_N; Aralkyl acyl-CoA:amino acid N-acyltransferase
  4. XM_017017338.2XP_016872827.1  glycine N-acyltransferase-like protein 2 isoform X1

    UniProtKB/Swiss-Prot
    Q8WU03
    UniProtKB/TrEMBL
    A0A024R4Z5
    Conserved Domains (2) summary
    pfam08444
    Location:202290
    Gly_acyl_tr_C; Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region
    pfam06021
    Location:10199
    Gly_acyl_tr_N; Aralkyl acyl-CoA:amino acid N-acyltransferase
  5. XM_011544809.3XP_011543111.1  glycine N-acyltransferase-like protein 2 isoform X2

    Conserved Domains (2) summary
    pfam08444
    Location:161249
    Gly_acyl_tr_C; Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region
    pfam06021
    Location:1158
    Gly_acyl_tr_N; Aralkyl acyl-CoA:amino acid N-acyltransferase
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