U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

SPATA19 spermatogenesis associated 19 [ Homo sapiens (human) ]

Gene ID: 219938, updated on 13-Oct-2022

Summary

Official Symbol
SPATA19provided by HGNC
Official Full Name
spermatogenesis associated 19provided by HGNC
Primary source
HGNC:HGNC:30614
See related
Ensembl:ENSG00000166118 MIM:609805; AllianceGenome:HGNC:30614
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CT132; SPAS1; spergen1
Summary
Predicted to be involved in cell differentiation and spermatogenesis. Predicted to be located in mitochondrial outer membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis (RPKM 27.4) See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See SPATA19 in Genome Data Viewer
Location:
11q25
Exon count:
8
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (133835930..133845513, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (133882925..133887807, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (133710526..133715408, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 715 Neighboring gene long intergenic non-protein coding RNA 2743 Neighboring gene calponin 2 pseudogene Neighboring gene microRNA 4697 Neighboring gene immunoglobulin superfamily member 9B

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ25851

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 
involved_in sperm mitochondrion organization ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in spermatogenesis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in mitochondrial outer membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in sperm flagellum ISS
Inferred from Sequence or Structural Similarity
more info
 
is_active_in sperm midpiece IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in sperm midpiece ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
spermatogenesis-associated protein 19, mitochondrial
Names
cancer/testis antigen 132
spergen-1
spermatogenic cell-specific gene 1 protein
spermatogenic specific-gene1
testis secretory sperm-binding protein Li 243mP

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001291992.2NP_001278921.1  spermatogenesis-associated protein 19, mitochondrial precursor

    See identical proteins and their annotated locations for NP_001278921.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 3' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AK098717, AP001979, BX096445
    Consensus CDS
    CCDS8493.1
    UniProtKB/Swiss-Prot
    Q7Z5L4, Q8N7A9
    UniProtKB/TrEMBL
    A0A140VKB6
    Related
    ENSP00000435248.1, ENST00000532889.1
    Conserved Domains (1) summary
    pfam15212
    Location:25167
    SPATA19; Spermatogenesis-associated protein 19, mitochondrial
  2. NM_174927.3NP_777587.1  spermatogenesis-associated protein 19, mitochondrial precursor

    See identical proteins and their annotated locations for NP_777587.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AP001979, BC058039, BX096445
    Consensus CDS
    CCDS8493.1
    UniProtKB/Swiss-Prot
    Q7Z5L4, Q8N7A9
    UniProtKB/TrEMBL
    A0A140VKB6
    Related
    ENSP00000299140.3, ENST00000299140.8
    Conserved Domains (1) summary
    pfam15212
    Location:25167
    SPATA19; Spermatogenesis-associated protein 19, mitochondrial

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    133835930..133845513 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_947807.2 RNA Sequence

  2. XR_947806.2 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    133882925..133887807 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)