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TBCEL tubulin folding cofactor E like [ Homo sapiens (human) ]

Gene ID: 219899, updated on 13-Mar-2020

Summary

Official Symbol
TBCELprovided by HGNC
Official Full Name
tubulin folding cofactor E likeprovided by HGNC
Primary source
HGNC:HGNC:28115
See related
Ensembl:ENSG00000154114 MIM:610451
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
El; LRRC35
Expression
Ubiquitous expression in testis (RPKM 8.9), thyroid (RPKM 6.7) and 25 other tissues See more
Orthologs

Genomic context

See TBCEL in Genome Data Viewer
Location:
11q23.3
Exon count:
9
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (121024102..121090776)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (120894802..120962787)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene glutamate ionotropic receptor kainate type subunit 4 Neighboring gene uncharacterized LOC101929208 Neighboring gene high mobility group box 1 pseudogene 42 Neighboring gene HNF4 motif-containing MPRA enhancer 256 Neighboring gene tectorin alpha Neighboring gene uncharacterized LOC105369533

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ14177, MGC10233

Gene Ontology Provided by GOA

Function Evidence Code Pubs
alpha-tubulin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
microtubule cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
post-chaperonin tubulin folding pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
tubulin complex assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoskeleton IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
tubulin-specific chaperone cofactor E-like protein
Names
E-like
catastrophin
leucine rich repeat containing 35
leucine-rich repeat-containing protein 35
tubulin-specific chaperone e-like

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001130047.3NP_001123519.1  tubulin-specific chaperone cofactor E-like protein

    See identical proteins and their annotated locations for NP_001123519.1

    Status: VALIDATED

    Source sequence(s)
    AP000646, AP001929
    Consensus CDS
    CCDS31692.1
    UniProtKB/Swiss-Prot
    Q5QJ74
    Related
    ENSP00000437184.1, ENST00000529397.5
    Conserved Domains (4) summary
    COG4886
    Location:47225
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:5275
    LRR_RI; leucine-rich repeat [structural motif]
    pfam14580
    Location:191304
    LRR_9; Leucine-rich repeat
    cl00155
    Location:345419
    UBQ; Ubiquitin-like proteins
  2. NM_001363644.2NP_001350573.1  tubulin-specific chaperone cofactor E-like protein

    Status: VALIDATED

    Source sequence(s)
    AP000646, AP001929
    Consensus CDS
    CCDS31692.1
    Conserved Domains (4) summary
    COG4886
    Location:47225
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:5275
    LRR_RI; leucine-rich repeat [structural motif]
    pfam14580
    Location:191304
    LRR_9; Leucine-rich repeat
    cl00155
    Location:345419
    UBQ; Ubiquitin-like proteins
  3. NM_152715.5NP_689928.3  tubulin-specific chaperone cofactor E-like protein

    See identical proteins and their annotated locations for NP_689928.3

    Status: VALIDATED

    Source sequence(s)
    AP000646, AP001929
    Consensus CDS
    CCDS31692.1
    UniProtKB/Swiss-Prot
    Q5QJ74
    Related
    ENSP00000403925.2, ENST00000422003.6
    Conserved Domains (4) summary
    COG4886
    Location:47225
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:5275
    LRR_RI; leucine-rich repeat [structural motif]
    pfam14580
    Location:191304
    LRR_9; Leucine-rich repeat
    cl00155
    Location:345419
    UBQ; Ubiquitin-like proteins

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    121024102..121090776
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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