Format

Send to:

Choose Destination

SLC37A2 solute carrier family 37 member 2 [ Homo sapiens (human) ]

Gene ID: 219855, updated on 1-Jun-2020

Summary

Official Symbol
SLC37A2provided by HGNC
Official Full Name
solute carrier family 37 member 2provided by HGNC
Primary source
HGNC:HGNC:20644
See related
Ensembl:ENSG00000134955
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
pp11662
Expression
Broad expression in adrenal (RPKM 13.0), salivary gland (RPKM 12.4) and 18 other tissues See more
Orthologs

Genomic context

See SLC37A2 in Genome Data Viewer
Location:
11q24.2
Exon count:
19
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (125063067..125090516)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (124932963..124960412)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene CCDC15 divergent transcript Neighboring gene coiled-coil domain containing 15 Neighboring gene transmembrane protein 218 Neighboring gene keratin 18 pseudogene 59

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Pathways from PubChem

General gene information

Markers

Homology

Clone Names

  • FLJ00171, MGC71430

Gene Ontology Provided by GOA

Function Evidence Code Pubs
glucose 6-phosphate:inorganic phosphate antiporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
glucose 6-phosphate:inorganic phosphate antiporter activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
carbohydrate transport IEA
Inferred from Electronic Annotation
more info
 
glucose-6-phosphate transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
glucose-6-phosphate transport IDA
Inferred from Direct Assay
more info
PubMed 
glucose-6-phosphate transport TAS
Traceable Author Statement
more info
 
phosphate ion transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
phosphate ion transmembrane transport IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
glucose-6-phosphate exchanger SLC37A2
Names
solute carrier family 37 (glucose-6-phosphate transporter), member 2
solute carrier family 37 (glycerol-3-phosphate transporter), member 2
sugar phosphate exchanger 2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001145290.2NP_001138762.1  glucose-6-phosphate exchanger SLC37A2 isoform 2

    See identical proteins and their annotated locations for NP_001138762.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an exon in the coding region that causes a frameshift. The resulting isoform (2) has a distinct C-terminus compared to isoform 1.
    Source sequence(s)
    AK290314, AP001007
    Consensus CDS
    CCDS44757.1
    UniProtKB/Swiss-Prot
    Q8TED4
    Related
    ENSP00000384407.2, ENST00000403796.6
    Conserved Domains (2) summary
    cd06174
    Location:86481
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    TIGR00881
    Location:87463
    2A0104; phosphoglycerate transporter family protein
  2. NM_198277.3NP_938018.1  glucose-6-phosphate exchanger SLC37A2 isoform 1

    See identical proteins and their annotated locations for NP_938018.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AK074207, AP001007, BC051314
    Consensus CDS
    CCDS31714.1
    UniProtKB/Swiss-Prot
    Q8TED4
    Related
    ENSP00000311833.4, ENST00000308074.4
    Conserved Domains (1) summary
    cl27298
    Location:25478
    UhpC; Sugar phosphate permease [Carbohydrate transport and metabolism]

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    125063067..125090516
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_001747788.1 RNA Sequence

Support Center