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FAU FAU ubiquitin like and ribosomal protein S30 fusion [ Homo sapiens (human) ]

Gene ID: 2197, updated on 23-Sep-2022


Official Symbol
FAUprovided by HGNC
Official Full Name
FAU ubiquitin like and ribosomal protein S30 fusionprovided by HGNC
Primary source
See related
Ensembl:ENSG00000149806 MIM:134690; AllianceGenome:HGNC:3597
Gene type
protein coding
RefSeq status
Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
S30; FAU1; Fub1; Fubi; asr1; RPS30; MNSFbeta
This gene is the cellular homolog of the fox sequence in the Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV). It encodes a fusion protein consisting of the ubiquitin-like protein fubi at the N terminus and ribosomal protein S30 at the C terminus. It has been proposed that the fusion protein is post-translationally processed to generate free fubi and free ribosomal protein S30. Fubi is a member of the ubiquitin family, and ribosomal protein S30 belongs to the S30E family of ribosomal proteins. Whereas the function of fubi is currently unknown, ribosomal protein S30 is a component of the 40S subunit of the cytoplasmic ribosome and displays antimicrobial activity. Pseudogenes derived from this gene are present in the genome. Similar to ribosomal protein S30, ribosomal proteins S27a and L40 are synthesized as fusion proteins with ubiquitin. [provided by RefSeq, Nov 2014]
Ubiquitous expression in ovary (RPKM 446.2), bone marrow (RPKM 364.4) and 25 other tissues See more
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Genomic context

See FAU in Genome Data Viewer
Exon count:
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (65120630..65122134, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (65113909..65115413, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (64888102..64889606, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 11972 Neighboring gene transmembrane 7 superfamily member 2 Neighboring gene Sharpr-MPRA regulatory region 3974 Neighboring gene zinc finger HIT-type containing 2 Neighboring gene mitochondrial ribosomal protein L49 Neighboring gene synoviolin 1 Neighboring gene microRNA 6751

Genomic regions, transcripts, and products


  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018


GeneRIFs: Gene References Into Functions

What's a GeneRIF?

HIV-1 interactions

Protein interactions

Protein Gene Interaction Pubs
Rev rev HIV-1 Rev interacting protein, Finkel-Biskis-Reilly murine sarcoma virus ubiquitously expressed (FAU), is identified by the in-vitro binding experiments involving cytosolic or nuclear extracts from HeLa cells PubMed

Go to the HIV-1, Human Interaction Database

Pathways from PubChem


Products Interactant Other Gene Complex Source Pubs Description

General gene information



Clone Names

  • FLJ22986

Gene Ontology Provided by GOA

General protein information

Preferred Names
FAU ubiquitin-like and ribosomal protein S30
40S ribosomal protein S30
FAU-encoded ubiquitin-like protein
FBR-MuSV-associated ubiquitously expressed
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived)
monoclonal nonspecific suppressor factor beta
ribosomal protein S30
small ribosomal subunit protein eS30
ubiquitin-like protein fubi and ribosomal protein S30
ubiquitin-like-S30 fusion protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001997.5NP_001988.1  FAU ubiquitin-like and ribosomal protein S30 precursor

    See identical proteins and their annotated locations for NP_001988.1

    Status: REVIEWED

    Source sequence(s)
    AA449261, BC033877, BU602831
    Consensus CDS
    P35544, Q9H5V4
    ENSP00000435370.1, ENST00000529639.6
    Conserved Domains (2) summary
    Ubl_FUBI; ubiquitin-like (Ubl) domain found in ubiquitin-like protein FUBI and similar proteins
    Ribosomal_S30; Ribosomal protein S30

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly


  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    65120630..65122134 complement
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0


  1. NC_060935.1 Alternate T2T-CHM13v2.0

    65113909..65115413 complement
    GenBank, FASTA, Sequence Viewer (Graphics)