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Tns1 tensin 1 [ Mus musculus (house mouse) ]

Gene ID: 21961, updated on 5-Jan-2023

Summary

Official Symbol
Tns1provided by MGI
Official Full Name
tensin 1provided by MGI
Primary source
MGI:MGI:104552
See related
Ensembl:ENSMUSG00000055322 AllianceGenome:MGI:104552
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Tns; 1110018I21Rik; 1200014E20Rik; E030018G17Rik; E030037J05Rik
Summary
Predicted to enable actin binding activity. Acts upstream of or within cell-substrate junction assembly and fibroblast migration. Located in focal adhesion. Is expressed in several structures, including future midbrain; gut; metanephros; nasal process; and yolk sac. Orthologous to human TNS1 (tensin 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in lung adult (RPKM 128.6), bladder adult (RPKM 85.1) and 18 other tissues See more
Orthologs
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Genomic context

See Tns1 in Genome Data Viewer
Location:
1 C3; 1 38.17 cM
Exon count:
52
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (73949391..74163707, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (73910232..74124548, complement)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 6030407O03 gene Neighboring gene predicted gene 29183 Neighboring gene microRNA 6351 Neighboring gene predicted gene, 39664 Neighboring gene VISTA enhancer mm1630 Neighboring gene predicted gene, 31637 Neighboring gene RUN and FYVE domain containing 4 Neighboring gene chemokine (C-X-C motif) receptor 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2)  1 citation
  • Endonuclease-mediated (3) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables actin binding TAS
Traceable Author Statement
more info
PubMed 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables phosphoprotein phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within cell-substrate junction assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in fibroblast migration IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within fibroblast migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in cell junction IEA
Inferred from Electronic Annotation
more info
 
located_in cell-substrate junction IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
located_in focal adhesion IDA
Inferred from Direct Assay
more info
PubMed 
located_in focal adhesion ISO
Inferred from Sequence Orthology
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001289895.2NP_001276824.1  tensin-1 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks two in-frame exons in the 3' coding region, compared to variant 1, resulting in an isoform (b) that is shorter than isoform a.
    Source sequence(s)
    AC116419, AC117757
    Consensus CDS
    CCDS48288.2
    UniProtKB/TrEMBL
    A0A087WQS0, Q7TSV1, Q8C6V6, Q9DBT6
    Related
    ENSMUSP00000140317.2, ENSMUST00000191104.7
    Conserved Domains (5) summary
    cd09927
    Location:15911706
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    smart00404
    Location:248363
    PTPc_motif; Protein tyrosine phosphatase, catalytic domain motif
    cd01213
    Location:17281861
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
    pfam10409
    Location:350476
    PTEN_C2; C2 domain of PTEN tumour-suppressor protein
    cl00040
    Location:75108
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
  2. NM_001413787.1NP_001400716.1  tensin-1 isoform c

    Status: VALIDATED

    Source sequence(s)
    AC116419, AC117757
  3. NM_001413788.1NP_001400717.1  tensin-1 isoform d

    Status: VALIDATED

    Source sequence(s)
    AC116419
  4. NM_001413789.1NP_001400718.1  tensin-1 isoform d

    Status: VALIDATED

    Source sequence(s)
    AC116419, AC117757
  5. NM_001413790.1NP_001400719.1  tensin-1 isoform e

    Status: VALIDATED

    Source sequence(s)
    AC116419, AC117757
  6. NM_001413791.1NP_001400720.1  tensin-1 isoform f

    Status: VALIDATED

    Source sequence(s)
    AC116419, AC117757
  7. NM_027884.4NP_082160.3  tensin-1 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
    Source sequence(s)
    AC116419, AC117757
    Consensus CDS
    CCDS78614.1
    UniProtKB/Swiss-Prot
    E9Q0S6
    UniProtKB/TrEMBL
    E9Q0S6
    Related
    ENSMUSP00000127715.2, ENSMUST00000169786.8
    Conserved Domains (5) summary
    cd09927
    Location:16121727
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    smart00404
    Location:248363
    PTPc_motif; Protein tyrosine phosphatase, catalytic domain motif
    cd01213
    Location:17491882
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
    pfam10409
    Location:350476
    PTEN_C2; C2 domain of PTEN tumour-suppressor protein
    cl00040
    Location:75108
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    73949391..74163707 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030252982.1XP_030108842.1  tensin-1 isoform X8

    Conserved Domains (6) summary
    cd09927
    Location:16401755
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    PHA03247
    Location:10671643
    PHA03247; large tegument protein UL36; Provisional
    cd01213
    Location:17771910
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
    pfam10409
    Location:350476
    PTEN_C2; C2 domain of PTEN tumor-suppressor protein
    cl00040
    Location:75108
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cl28904
    Location:185343
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
  2. XM_006495871.4XP_006495934.1  tensin-1 isoform X7

    Conserved Domains (6) summary
    cd09927
    Location:16421757
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    PHA03247
    Location:10691645
    PHA03247; large tegument protein UL36; Provisional
    cd01213
    Location:17791912
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
    pfam10409
    Location:350476
    PTEN_C2; C2 domain of PTEN tumor-suppressor protein
    cl00040
    Location:75108
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cl28904
    Location:185343
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
  3. XM_017319864.1XP_017175353.1  tensin-1 isoform X15

    Related
    ENSMUSP00000140254.2, ENSMUST00000187584.7
    Conserved Domains (7) summary
    cd09927
    Location:15951710
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    PHA03247
    Location:9121598
    PHA03247; large tegument protein UL36; Provisional
    PHA03307
    Location:6891081
    PHA03307; transcriptional regulator ICP4; Provisional
    cd01213
    Location:17321865
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
    pfam10409
    Location:354480
    PTEN_C2; C2 domain of PTEN tumor-suppressor protein
    cl00040
    Location:79112
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cl28904
    Location:189347
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
  4. XM_017319860.1XP_017175349.1  tensin-1 isoform X12

    Conserved Domains (7) summary
    cd09927
    Location:16031718
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    PHA03247
    Location:9121606
    PHA03247; large tegument protein UL36; Provisional
    PHA03307
    Location:6891081
    PHA03307; transcriptional regulator ICP4; Provisional
    cd01213
    Location:17401873
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
    pfam10409
    Location:354480
    PTEN_C2; C2 domain of PTEN tumor-suppressor protein
    cl00040
    Location:79112
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cl28904
    Location:189347
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
  5. XM_017319859.1XP_017175348.1  tensin-1 isoform X10

    Conserved Domains (6) summary
    cd09927
    Location:16161731
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    PHA03247
    Location:10431619
    PHA03247; large tegument protein UL36; Provisional
    cd01213
    Location:17531886
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
    pfam10409
    Location:354480
    PTEN_C2; C2 domain of PTEN tumor-suppressor protein
    cl00040
    Location:79112
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cl28904
    Location:189347
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
  6. XM_036163578.1XP_036019471.1  tensin-1 isoform X4

    Conserved Domains (6) summary
    cd09927
    Location:16361751
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    PHA03247
    Location:9641482
    PHA03247; large tegument protein UL36; Provisional
    cd01213
    Location:17731906
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
    pfam10409
    Location:354480
    PTEN_C2; C2 domain of PTEN tumor-suppressor protein
    cl00040
    Location:61116
    C1; protein kinase C conserved region 1 (C1 domain) superfamily
    cl28904
    Location:189347
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
  7. XM_017319847.1XP_017175336.1  tensin-1 isoform X2

    Conserved Domains (6) summary
    cd09927
    Location:16441759
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    PHA03247
    Location:10711647
    PHA03247; large tegument protein UL36; Provisional
    cd01213
    Location:17811914
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
    pfam10409
    Location:354480
    PTEN_C2; C2 domain of PTEN tumor-suppressor protein
    cl00040
    Location:79112
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cl28904
    Location:189347
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
  8. XM_017319866.1XP_017175355.1  tensin-1 isoform X23

    Conserved Domains (7) summary
    cd09927
    Location:14751590
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    PHA03247
    Location:9071478
    PHA03247; large tegument protein UL36; Provisional
    cd01213
    Location:16121745
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
    pfam03154
    Location:5801028
    Atrophin-1; Atrophin-1 family
    pfam10409
    Location:354480
    PTEN_C2; C2 domain of PTEN tumor-suppressor protein
    cl00040
    Location:79112
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cl28904
    Location:189347
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
  9. XM_030252984.1XP_030108844.1  tensin-1 isoform X22

    Conserved Domains (7) summary
    cd09927
    Location:15061621
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    PHA03247
    Location:9461509
    PHA03247; large tegument protein UL36; Provisional
    cd01213
    Location:16431776
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
    pfam03154
    Location:5801028
    Atrophin-1; Atrophin-1 family
    pfam10409
    Location:354480
    PTEN_C2; C2 domain of PTEN tumor-suppressor protein
    cl00040
    Location:79112
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cl28904
    Location:189347
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
  10. XM_017319865.1XP_017175354.1  tensin-1 isoform X21

    Conserved Domains (6) summary
    cd09927
    Location:15271642
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    PHA03247
    Location:9761530
    PHA03247; large tegument protein UL36; Provisional
    cd01213
    Location:16641797
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
    pfam10409
    Location:354480
    PTEN_C2; C2 domain of PTEN tumor-suppressor protein
    cl00040
    Location:79112
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cl28904
    Location:189347
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
  11. XM_017319863.1XP_017175352.1  tensin-1 isoform X14

    Conserved Domains (7) summary
    cd09927
    Location:15971712
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    PHA03247
    Location:9141600
    PHA03247; large tegument protein UL36; Provisional
    PHA03307
    Location:6911083
    PHA03307; transcriptional regulator ICP4; Provisional
    cd01213
    Location:17341867
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
    pfam10409
    Location:354480
    PTEN_C2; C2 domain of PTEN tumor-suppressor protein
    cl00040
    Location:79112
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cl28904
    Location:189347
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
  12. XM_036163588.1XP_036019481.1  tensin-1 isoform X11

    Conserved Domains (6) summary
    cd09927
    Location:16101725
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    PHA03247
    Location:10451613
    PHA03247; large tegument protein UL36; Provisional
    cd01213
    Location:17471880
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
    pfam10409
    Location:354480
    PTEN_C2; C2 domain of PTEN tumor-suppressor protein
    cl00040
    Location:61116
    C1; protein kinase C conserved region 1 (C1 domain) superfamily
    cl28904
    Location:189347
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
  13. XM_017319858.1XP_017175347.1  tensin-1 isoform X9

    Conserved Domains (6) summary
    cd09927
    Location:16181733
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    PHA03247
    Location:10451621
    PHA03247; large tegument protein UL36; Provisional
    cd01213
    Location:17551888
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
    pfam10409
    Location:354480
    PTEN_C2; C2 domain of PTEN tumor-suppressor protein
    cl00040
    Location:79112
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cl28904
    Location:189347
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
  14. XM_017319856.1XP_017175345.1  tensin-1 isoform X6

    Conserved Domains (6) summary
    cd09927
    Location:16251740
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    PHA03247
    Location:9661471
    PHA03247; large tegument protein UL36; Provisional
    cd01213
    Location:17621895
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
    pfam10409
    Location:354480
    PTEN_C2; C2 domain of PTEN tumor-suppressor protein
    cl00040
    Location:79112
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cl28904
    Location:189347
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
  15. XM_017319848.1XP_017175337.1  tensin-1 isoform X3

    Conserved Domains (6) summary
    cd09927
    Location:16381753
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    PHA03247
    Location:9661484
    PHA03247; large tegument protein UL36; Provisional
    cd01213
    Location:17751908
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
    pfam10409
    Location:354480
    PTEN_C2; C2 domain of PTEN tumor-suppressor protein
    cl00040
    Location:79112
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cl28904
    Location:189347
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
  16. XM_017319853.1XP_017175342.1  tensin-1 isoform X5

    Conserved Domains (6) summary
    cd09927
    Location:16331748
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    PHA03247
    Location:9661479
    PHA03247; large tegument protein UL36; Provisional
    cd01213
    Location:17701903
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
    pfam10409
    Location:354480
    PTEN_C2; C2 domain of PTEN tumor-suppressor protein
    cl00040
    Location:79112
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cl28904
    Location:189347
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
  17. XM_006495867.2XP_006495930.2  tensin-1 isoform X1

    Conserved Domains (6) summary
    cd09927
    Location:16461761
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    PHA03247
    Location:10731649
    PHA03247; large tegument protein UL36; Provisional
    cd01213
    Location:17831916
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
    pfam10409
    Location:354480
    PTEN_C2; C2 domain of PTEN tumor-suppressor protein
    cl00040
    Location:79112
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cl28904
    Location:189347
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
  18. XM_006495878.4XP_006495941.1  tensin-1 isoform X24

    See identical proteins and their annotated locations for XP_006495941.1

    Conserved Domains (5) summary
    cd09927
    Location:14921607
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    PHA03247
    Location:9191495
    PHA03247; large tegument protein UL36; Provisional
    cd01213
    Location:16291762
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
    pfam10409
    Location:200326
    PTEN_C2; C2 domain of PTEN tumor-suppressor protein
    cl28904
    Location:35193
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
  19. XM_017319862.3XP_017175351.1  tensin-1 isoform X13

    Conserved Domains (6) summary
    cd09927
    Location:16221737
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    PHA03247
    Location:10491625
    PHA03247; large tegument protein UL36; Provisional
    cd01213
    Location:17591892
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
    pfam10409
    Location:330456
    PTEN_C2; C2 domain of PTEN tumor-suppressor protein
    cl00040
    Location:5588
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cl28904
    Location:165323
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
  20. XM_030252983.1XP_030108843.1  tensin-1 isoform X17

    Conserved Domains (6) summary
    cd09927
    Location:15991714
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    PHA03247
    Location:10261602
    PHA03247; large tegument protein UL36; Provisional
    cd01213
    Location:17361869
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
    pfam10409
    Location:309435
    PTEN_C2; C2 domain of PTEN tumor-suppressor protein
    cl00040
    Location:3467
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cl28904
    Location:144302
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
  21. XM_006495872.1XP_006495935.1  tensin-1 isoform X16

    Conserved Domains (6) summary
    cd09927
    Location:16011716
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    PHA03247
    Location:10281604
    PHA03247; large tegument protein UL36; Provisional
    cd01213
    Location:17381871
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
    pfam10409
    Location:309435
    PTEN_C2; C2 domain of PTEN tumor-suppressor protein
    cl00040
    Location:3467
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cl28904
    Location:144302
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
  22. XM_006495875.2XP_006495938.1  tensin-1 isoform X20

    Conserved Domains (5) summary
    cd09927
    Location:15531668
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    PHA03247
    Location:9801556
    PHA03247; large tegument protein UL36; Provisional
    cd01213
    Location:16901823
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
    pfam10409
    Location:261387
    PTEN_C2; C2 domain of PTEN tumor-suppressor protein
    cl28904
    Location:96254
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
  23. XM_036163612.1XP_036019505.1  tensin-1 isoform X26

    Conserved Domains (5) summary
    cd09927
    Location:14821597
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    PHA03247
    Location:8101328
    PHA03247; large tegument protein UL36; Provisional
    cd01213
    Location:16191752
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
    pfam10409
    Location:200326
    PTEN_C2; C2 domain of PTEN tumor-suppressor protein
    cl28904
    Location:35193
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
  24. XM_011238476.3XP_011236778.1  tensin-1 isoform X24

    See identical proteins and their annotated locations for XP_011236778.1

    Conserved Domains (5) summary
    cd09927
    Location:14921607
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    PHA03247
    Location:9191495
    PHA03247; large tegument protein UL36; Provisional
    cd01213
    Location:16291762
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
    pfam10409
    Location:200326
    PTEN_C2; C2 domain of PTEN tumor-suppressor protein
    cl28904
    Location:35193
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
  25. XM_006495874.4XP_006495937.1  tensin-1 isoform X19

    Conserved Domains (5) summary
    cd09927
    Location:15681683
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    PHA03247
    Location:9951571
    PHA03247; large tegument protein UL36; Provisional
    cd01213
    Location:17051838
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
    pfam10409
    Location:276402
    PTEN_C2; C2 domain of PTEN tumor-suppressor protein
    cl28904
    Location:111269
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
  26. XM_030252985.2XP_030108845.1  tensin-1 isoform X25

    Conserved Domains (5) summary
    cd09927
    Location:14901605
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    PHA03247
    Location:9171493
    PHA03247; large tegument protein UL36; Provisional
    cd01213
    Location:16271760
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
    pfam10409
    Location:200326
    PTEN_C2; C2 domain of PTEN tumor-suppressor protein
    cl28904
    Location:35193
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
  27. XM_006495877.4XP_006495940.1  tensin-1 isoform X24

    See identical proteins and their annotated locations for XP_006495940.1

    Conserved Domains (5) summary
    cd09927
    Location:14921607
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    PHA03247
    Location:9191495
    PHA03247; large tegument protein UL36; Provisional
    cd01213
    Location:16291762
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
    pfam10409
    Location:200326
    PTEN_C2; C2 domain of PTEN tumor-suppressor protein
    cl28904
    Location:35193
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
  28. XM_006495880.4XP_006495943.1  tensin-1 isoform X24

    See identical proteins and their annotated locations for XP_006495943.1

    Conserved Domains (5) summary
    cd09927
    Location:14921607
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    PHA03247
    Location:9191495
    PHA03247; large tegument protein UL36; Provisional
    cd01213
    Location:16291762
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
    pfam10409
    Location:200326
    PTEN_C2; C2 domain of PTEN tumor-suppressor protein
    cl28904
    Location:35193
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
  29. XM_006495873.2XP_006495936.2  tensin-1 isoform X18

    Conserved Domains (5) summary
    cd09927
    Location:15521667
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    PHA03247
    Location:9791555
    PHA03247; large tegument protein UL36; Provisional
    cd01213
    Location:16891822
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
    pfam10409
    Location:260386
    PTEN_C2; C2 domain of PTEN tumor-suppressor protein
    cl28904
    Location:95253
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
  30. XM_011238477.2XP_011236779.1  tensin-1 isoform X24

    See identical proteins and their annotated locations for XP_011236779.1

    Conserved Domains (5) summary
    cd09927
    Location:14921607
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    PHA03247
    Location:9191495
    PHA03247; large tegument protein UL36; Provisional
    cd01213
    Location:16291762
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
    pfam10409
    Location:200326
    PTEN_C2; C2 domain of PTEN tumor-suppressor protein
    cl28904
    Location:35193
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
  31. XM_006495879.1XP_006495942.1  tensin-1 isoform X24

    See identical proteins and their annotated locations for XP_006495942.1

    Conserved Domains (5) summary
    cd09927
    Location:14921607
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    PHA03247
    Location:9191495
    PHA03247; large tegument protein UL36; Provisional
    cd01213
    Location:16291762
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
    pfam10409
    Location:200326
    PTEN_C2; C2 domain of PTEN tumor-suppressor protein
    cl28904
    Location:35193
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
  32. XM_036163617.1XP_036019510.1  tensin-1 isoform X26

    Conserved Domains (5) summary
    cd09927
    Location:14821597
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    PHA03247
    Location:8101328
    PHA03247; large tegument protein UL36; Provisional
    cd01213
    Location:16191752
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
    pfam10409
    Location:200326
    PTEN_C2; C2 domain of PTEN tumor-suppressor protein
    cl28904
    Location:35193
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
  33. XM_036163609.1XP_036019502.1  tensin-1 isoform X24

    Conserved Domains (5) summary
    cd09927
    Location:14921607
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    PHA03247
    Location:9191495
    PHA03247; large tegument protein UL36; Provisional
    cd01213
    Location:16291762
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
    pfam10409
    Location:200326
    PTEN_C2; C2 domain of PTEN tumor-suppressor protein
    cl28904
    Location:35193
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
  34. XM_006495881.4XP_006495944.1  tensin-1 isoform X24

    See identical proteins and their annotated locations for XP_006495944.1

    Conserved Domains (5) summary
    cd09927
    Location:14921607
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    PHA03247
    Location:9191495
    PHA03247; large tegument protein UL36; Provisional
    cd01213
    Location:16291762
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
    pfam10409
    Location:200326
    PTEN_C2; C2 domain of PTEN tumor-suppressor protein
    cl28904
    Location:35193
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
  35. XM_006495882.4XP_006495945.1  tensin-1 isoform X24

    See identical proteins and their annotated locations for XP_006495945.1

    Related
    ENSMUSP00000140094.2, ENSMUST00000185702.7
    Conserved Domains (5) summary
    cd09927
    Location:14921607
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    PHA03247
    Location:9191495
    PHA03247; large tegument protein UL36; Provisional
    cd01213
    Location:16291762
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
    pfam10409
    Location:200326
    PTEN_C2; C2 domain of PTEN tumor-suppressor protein
    cl28904
    Location:35193
    PTP_DSP_cys; cys-based protein tyrosine phosphatase and dual-specificity phosphatase superfamily
  36. XM_030252988.1XP_030108848.1  tensin-1 isoform X33

    Conserved Domains (3) summary
    cd09927
    Location:842957
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    PHA03247
    Location:274845
    PHA03247; large tegument protein UL36; Provisional
    cd01213
    Location:9791112
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
  37. XM_036163624.1XP_036019517.1  tensin-1 isoform X32

    Conserved Domains (3) summary
    cd09927
    Location:8861001
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    PHA03247
    Location:343889
    PHA03247; large tegument protein UL36; Provisional
    cd01213
    Location:10231156
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
  38. XM_030252987.1XP_030108847.1  tensin-1 isoform X31

    Conserved Domains (3) summary
    cd09927
    Location:9641079
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    PHA03247
    Location:282931
    PHA03247; large tegument protein UL36; Provisional
    cd01213
    Location:11011234
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
  39. XM_036163621.1XP_036019514.1  tensin-1 isoform X30

    Conserved Domains (3) summary
    cd09927
    Location:9771092
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    PHA03247
    Location:412944
    PHA03247; large tegument protein UL36; Provisional
    cd01213
    Location:11141247
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
  40. XM_030252986.1XP_030108846.1  tensin-1 isoform X29

    Conserved Domains (3) summary
    cd09927
    Location:9851100
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    PHA03247
    Location:412952
    PHA03247; large tegument protein UL36; Provisional
    cd01213
    Location:11221255
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
  41. XM_036163620.1XP_036019513.1  tensin-1 isoform X28

    Conserved Domains (3) summary
    cd09927
    Location:10051120
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    PHA03247
    Location:333851
    PHA03247; large tegument protein UL36; Provisional
    cd01213
    Location:11421275
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
  42. XM_006495883.2XP_006495946.1  tensin-1 isoform X27

    Conserved Domains (3) summary
    cd09927
    Location:10131128
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    PHA03247
    Location:440980
    PHA03247; large tegument protein UL36; Provisional
    cd01213
    Location:11501283
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_177169.2: Suppressed sequence

    Description
    NM_177169.2: This RefSeq was permanently suppressed because it contains the wrong CDS.