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YPEL4 yippee like 4 [ Homo sapiens (human) ]

Gene ID: 219539, updated on 12-Aug-2022

Summary

Official Symbol
YPEL4provided by HGNC
Official Full Name
yippee like 4provided by HGNC
Primary source
HGNC:HGNC:18328
See related
Ensembl:ENSG00000166793 MIM:609725; AllianceGenome:HGNC:18328
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to enable metal ion binding activity. Predicted to be located in nucleolus. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in brain (RPKM 4.8), bone marrow (RPKM 3.2) and 12 other tissues See more
Orthologs
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Genomic context

See YPEL4 in Genome Data Viewer
Location:
11q12.1
Exon count:
6
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (57645087..57649912, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (57595261..57600086, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (57412560..57417385, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene serpin family G member 1 Neighboring gene microRNA 130a Neighboring gene cleavage factor polyribonucleotide kinase subunit 1 Neighboring gene zinc finger DHHC-type palmitoyltransferase 5

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

General gene information

Markers

Homology

Clone Names

  • FLJ30213, MGC102723, MGC138324

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001363487.2NP_001350416.1  protein yippee-like 4

    Status: VALIDATED

    Source sequence(s)
    AP000662
    Consensus CDS
    CCDS7963.1
    UniProtKB/Swiss-Prot
    Q65Z98
    UniProtKB/TrEMBL
    A0A024R4Y8
    Conserved Domains (1) summary
    cl13152
    Location:28118
    RLR_C_like; C-terminal domain of Retinoic acid-inducible gene (RIG)-I-like Receptors, Cereblon (CRBN), and similar protein domains
  2. NM_145008.3NP_659445.1  protein yippee-like 4

    See identical proteins and their annotated locations for NP_659445.1

    Status: VALIDATED

    Source sequence(s)
    AB098738
    Consensus CDS
    CCDS7963.1
    UniProtKB/Swiss-Prot
    Q65Z98, Q96NS1
    UniProtKB/TrEMBL
    A0A024R4Y8
    Related
    ENSP00000300022.3, ENST00000300022.8
    Conserved Domains (1) summary
    cl13152
    Location:28118
    RLR_C_like; C-terminal domain of Retinoic acid-inducible gene (RIG)-I-like Receptors, Cereblon (CRBN), and similar protein domains

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    57645087..57649912 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047426531.1XP_047282487.1  protein yippee-like 4 isoform X1

    UniProtKB/Swiss-Prot
    Q65Z98
    UniProtKB/TrEMBL
    A0A024R4Y8
    Related
    ENSP00000432648.1, ENST00000524669.5

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    57595261..57600086 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)