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OR5AS1 olfactory receptor family 5 subfamily AS member 1 [ Homo sapiens (human) ]

Gene ID: 219447, updated on 22-Sep-2022

Summary

Official Symbol
OR5AS1provided by HGNC
Official Full Name
olfactory receptor family 5 subfamily AS member 1provided by HGNC
Primary source
HGNC:HGNC:15261
See related
Ensembl:ENSG00000181785 AllianceGenome:HGNC:15261
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR11-168
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Orthologs
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Genomic context

See OR5AS1 in Genome Data Viewer
Location:
11q12.1
Exon count:
2
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (56027654..56038191)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (55965991..55976529)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (55795130..55805667)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 5 subfamily F member 1 Neighboring gene olfactory receptor family 5 subfamily F member 2 pseudogene Neighboring gene olfactory receptor family 5 subfamily AQ member 1 pseudogene Neighboring gene olfactory receptor family 5 subfamily J member 1 pseudogene

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables odorant binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
olfactory receptor 5AS1
Names
olfactory receptor OR11-168

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001001921.2NP_001001921.1  olfactory receptor 5AS1

    See identical proteins and their annotated locations for NP_001001921.1

    Status: VALIDATED

    Source sequence(s)
    AC068339
    Consensus CDS
    CCDS31516.1
    UniProtKB/Swiss-Prot
    Q6IFB8, Q8N127
    UniProtKB/TrEMBL
    A0A126GVD4
    Related
    ENSP00000493325.1, ENST00000641320.1
    Conserved Domains (1) summary
    cd15945
    Location:12303
    7tmA_OR5C1-like; olfactory receptor subfamily 5C1 and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    56027654..56038191
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    55965991..55976529
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)