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ATAD3C ATPase family AAA domain containing 3C [ Homo sapiens (human) ]

Gene ID: 219293, updated on 6-Nov-2022

Summary

Official Symbol
ATAD3Cprovided by HGNC
Official Full Name
ATPase family AAA domain containing 3Cprovided by HGNC
Primary source
HGNC:HGNC:32151
See related
Ensembl:ENSG00000215915 MIM:617227; AllianceGenome:HGNC:32151
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to enable zinc ion binding activity. Predicted to be involved in mitochondrion organization. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in thyroid (RPKM 1.1), kidney (RPKM 0.9) and 25 other tissues See more
Orthologs
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Genomic context

See ATAD3C in Genome Data Viewer
Location:
1p36.33
Exon count:
12
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (1449689..1470163)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (884061..904534)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (1385069..1405543)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107985729 Neighboring gene long intergenic non-protein coding RNA 1770 Neighboring gene Sharpr-MPRA regulatory region 8235 Neighboring gene von Willebrand factor A domain containing 1 Neighboring gene ATPase family AAA domain containing 3B Neighboring gene ATPase family AAA domain containing 3A

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ34599, FLJ37183

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in mitochondrion organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in mitochondrion IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
ATPase family AAA domain-containing protein 3C
Names
ATPase family, AAA domain containing 3A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001039211.3NP_001034300.2  ATPase family AAA domain-containing protein 3C

    See identical proteins and their annotated locations for NP_001034300.2

    Status: VALIDATED

    Source sequence(s)
    AL157945, AL391244
    Consensus CDS
    CCDS44039.1
    UniProtKB/Swiss-Prot
    Q5T2N8, Q8N1Z5
    Related
    ENSP00000368062.2, ENST00000378785.7
    Conserved Domains (2) summary
    COG0464
    Location:164359
    SpoVK; AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms]
    pfam00004
    Location:173300
    AAA; ATPase family associated with various cellular activities (AAA)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    1449689..1470163
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    884061..904534
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_198466.1: Suppressed sequence

    Description
    NM_198466.1: This RefSeq record was removed by NCBI staff. Contact info@ncbi.nlm.nih.gov for further information.