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Tmem260 transmembrane protein 260 [ Mus musculus (house mouse) ]

Gene ID: 218989, updated on 26-Sep-2022

Summary

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Official Symbol
Tmem260provided by MGI
Official Full Name
transmembrane protein 260provided by MGI
Primary source
MGI:MGI:2443219
See related
Ensembl:ENSMUSG00000036339 AllianceGenome:MGI:2443219
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
5930435P15; 6720456H20Rik
Summary
Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human TMEM260 (transmembrane protein 260). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in adrenal adult (RPKM 8.9), ovary adult (RPKM 7.1) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Tmem260 in Genome Data Viewer
Location:
14; 14 C1
Exon count:
24
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (48683580..48797640)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (48446123..48560183)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene actin related protein 2/3 complex, subunit 1A pseudogene Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene RIKEN cDNA 4930572G02 gene Neighboring gene predicted gene, 35766

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Yokoyama S, et al. Dev Cell, 2009 Dec. PMID 20059953, Free PMC Article
  2. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  3. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article

See all (13) citations in PubMed

See citations in PubMed for homologs of this gene provided by HomoloGene

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
transmembrane protein 260
Names
UPF0679 protein C14orf101 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001310584.1 → NP_001297513.1  transmembrane protein 260 isoform 2

    See identical proteins and their annotated locations for NP_001297513.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus than isoform 1.
    Source sequence(s)
    AK031240, BC059217, BY085085
    Consensus CDS
    CCDS79318.1
    UniProtKB/Swiss-Prot
    Q8BMD6
    Related
    ENSMUSP00000118376.2, ENSMUST00000124720.8
    Conserved Domains (1) summary
    cl21590
    Location:1 → 51
    PMT_2; Dolichyl-phosphate-mannose-protein mannosyltransferase

  2. NM_172600.4 → NP_766188.3  transmembrane protein 260 isoform 1

    See identical proteins and their annotated locations for NP_766188.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AK032809, AK141246, BC059217
    Consensus CDS
    CCDS26993.2
    UniProtKB/Swiss-Prot
    Q8BMD6, Q8BYU4
    Related
    ENSMUSP00000107364.3, ENSMUST00000111735.10
    Conserved Domains (1) summary
    pfam11028
    Location:48 → 203
    DUF2723; Protein of unknown function (DUF2723)

RNA

  1. NR_132324.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks two alternate internal exons, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AK031240, AK040456, AK141246, BC059217

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    48683580..48797640
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011245017.4 → XP_011243319.1  transmembrane protein 260 isoform X3

    Conserved Domains (1) summary
    pfam11028
    Location:48 → 203
    DUF2723; Protein of unknown function (DUF2723)

  2. XM_011245018.4 → XP_011243320.1  transmembrane protein 260 isoform X4

    Conserved Domains (1) summary
    pfam11028
    Location:48 → 203
    DUF2723; Protein of unknown function (DUF2723)

  3. XM_030247753.2 → XP_030103613.1  transmembrane protein 260 isoform X2

    Conserved Domains (1) summary
    cl21590
    Location:1 → 51
    PMT_2; Dolichyl-phosphate-mannose-protein mannosyltransferase

  4. XM_036158559.1 → XP_036014452.1  transmembrane protein 260 isoform X1

    Conserved Domains (1) summary
    cl21590
    Location:12 → 99
    PMT_2; Dolichyl-phosphate-mannose-protein mannosyltransferase

RNA

  1. XR_003950840.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8BMD6.2 GenPept UniProtKB/Swiss-Prot:Q8BMD6

Gene LinkOut

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