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Sema3g sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G [ Mus musculus (house mouse) ]

Gene ID: 218877, updated on 8-Dec-2018

Summary

Official Symbol
Sema3gprovided by MGI
Official Full Name
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Gprovided by MGI
Primary source
MGI:MGI:3041242
See related
Ensembl:ENSMUSG00000021904
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AK129018
Expression
Biased expression in lung adult (RPKM 46.9), kidney adult (RPKM 14.8) and 6 other tissues See more
Orthologs

Genomic context

See Sema3g in Genome Data Viewer
Location:
14; 14 B
Exon count:
17
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 14 NC_000080.6 (31217873..31230352)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (32031059..32042697)

Chromosome 14 - NC_000080.6Genomic Context describing neighboring genes Neighboring gene nischarin Neighboring gene troponin C, cardiac/slow skeletal Neighboring gene PHD finger protein 7 Neighboring gene Brca1 associated protein 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from BioSystems

  • Axon guidance, organism-specific biosystem (from KEGG)
    Axon guidance, organism-specific biosystemAxon guidance represents a key stage in the formation of neuronal network. Axons are guided by a variety of guidance factors, such as netrins, ephrins, Slits, and semaphorins. These guidance cues are...
  • Axon guidance, conserved biosystem (from KEGG)
    Axon guidance, conserved biosystemAxon guidance represents a key stage in the formation of neuronal network. Axons are guided by a variety of guidance factors, such as netrins, ephrins, Slits, and semaphorins. These guidance cues are...

General gene information

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
chemorepellent activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
neuropilin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
semaphorin receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
signaling receptor binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
negative chemotaxis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of axon extension IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of axon extension involved in axon guidance IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
neural crest cell migration IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of cell migration IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
semaphorin-plexin signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
extracellular region IEA
Inferred from Electronic Annotation
more info
 
extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
semaphorin-3G
Names
Semaphorin 3G

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001025379.1NP_001020550.1  semaphorin-3G precursor

    See identical proteins and their annotated locations for NP_001020550.1

    Status: PROVISIONAL

    Source sequence(s)
    AB127607
    Consensus CDS
    CCDS26908.1
    UniProtKB/Swiss-Prot
    Q4LFA9
    Related
    ENSMUSP00000087643.2, ENSMUST00000090180.3
    Conserved Domains (3) summary
    cd05871
    Location:591676
    Ig_Semaphorin_classIII; Immunoglobulin (Ig)-like domain of class III semaphorin
    smart00423
    Location:521567
    PSI; domain found in Plexins, Semaphorins and Integrins
    cl15693
    Location:49522
    Sema; The Sema domain, a protein interacting module, of semaphorins and plexins

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000080.6 Reference GRCm38.p4 C57BL/6J

    Range
    31217873..31230352
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006518821.3XP_006518884.1  semaphorin-3G isoform X1

    Conserved Domains (3) summary
    cd05871
    Location:554639
    Ig_Semaphorin_classIII; Immunoglobulin (Ig)-like domain of class III semaphorin
    smart00423
    Location:484530
    PSI; domain found in Plexins, Semaphorins and Integrins
    cl15693
    Location:12485
    Sema; The Sema domain, a protein interacting module, of semaphorins and plexins
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