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Spmap2 sperm microtubule associated protein 2 [ Mus musculus (house mouse) ]

Gene ID: 21830, updated on 1-Mar-2024

Summary

Official Symbol
Spmap2provided by MGI
Official Full Name
sperm microtubule associated protein 2provided by MGI
Primary source
MGI:MGI:1338756
See related
Ensembl:ENSMUSG00000020317 AllianceGenome:MGI:1338756
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Theg
Summary
Acts upstream of or within spermatogenesis. Predicted to be located in cytoplasm. Is expressed in large intestine; metanephros; ovary; submandibular gland; and testis. Orthologous to human THEG (theg spermatid protein). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis adult (RPKM 111.0) See more
Orthologs
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Genomic context

See Spmap2 in Genome Data Viewer
Location:
10 C1; 10 39.72 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (79412311..79422970, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (79576477..79587136, complement)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene phospholipid phosphatase 2 Neighboring gene microRNA 6909 Neighboring gene MIER family member 2 Neighboring gene predicted gene, 51808 Neighboring gene C2 calcium-dependent domain containing 4C Neighboring gene SHC (Src homology 2 domain containing) transforming protein 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within cell differentiation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
involved_in spermatogenesis IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within spermatogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm TAS
Traceable Author Statement
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
sperm microtubule associated protein 2
Names
testicular haploid expressed gene product
testicular haploid expressed gene protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011583.3NP_035713.1  sperm microtubule associated protein 2 isoform 1

    See identical proteins and their annotated locations for NP_035713.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AJ011834, AK017058, BC050970
    Consensus CDS
    CCDS23977.1
    UniProtKB/Swiss-Prot
    Q6P8H9, Q9JMB1, Q9QZ27
    Related
    ENSMUSP00000020566.7, ENSMUST00000020566.7
    Conserved Domains (1) summary
    pfam14912
    Location:209267
    THEG; Testicular haploid expressed repeat
  2. NM_199226.1NP_954696.1  sperm microtubule associated protein 2 isoform 2

    See identical proteins and their annotated locations for NP_954696.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an in-frame exon in the 5' coding region, compared to variant 1. The resulting isoform (2) lacks an internal segment in the N-terminal region, compared to isoform 1.
    Source sequence(s)
    BC050970, BE944097
    Consensus CDS
    CCDS23978.1
    UniProtKB/Swiss-Prot
    Q9JMB1
    Related
    ENSMUSP00000076647.7, ENSMUST00000077433.13
    Conserved Domains (1) summary
    pfam14912
    Location:185243
    THEG; Testicular haploid expressed repeat

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    79412311..79422970 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006513579.3XP_006513642.1  sperm microtubule associated protein 2 isoform X1

    Conserved Domains (1) summary
    pfam14912
    Location:212267
    THEG; Testicular haploid expressed repeat