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Cep170b centrosomal protein 170B [ Mus musculus (house mouse) ]

Gene ID: 217882, updated on 5-Mar-2024

Summary

Official Symbol
Cep170bprovided by MGI
Official Full Name
centrosomal protein 170Bprovided by MGI
Primary source
MGI:MGI:2145043
See related
Ensembl:ENSMUSG00000072825 AllianceGenome:MGI:2145043
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Kiaa0284; mKIAA0284
Summary
Predicted to be located in cytoplasm and microtubule. Is expressed in several structures, including alimentary system; brain; respiratory system; sensory organ; and urinary system. Orthologous to human CEP170B (centrosomal protein 170B). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in colon adult (RPKM 47.7), ovary adult (RPKM 28.6) and 26 other tissues See more
Orthologs
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Genomic context

See Cep170b in Genome Data Viewer
Location:
12 F1; 12 61.2 cM
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (112687950..112713026)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (112721514..112746592)

Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene zinc finger and BTB domain containing 42 Neighboring gene predicted gene, 30298 Neighboring gene predicted gene, 30238 Neighboring gene predicted gene, 46382 Neighboring gene microRNA 6940 Neighboring gene transmembrane protein 11 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E5361 Neighboring gene phospholipase D family member 4

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
located_in microtubule IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
centrosomal protein of 170 kDa protein B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001024602.4NP_001019773.2  centrosomal protein of 170 kDa protein B isoform 1

    See identical proteins and their annotated locations for NP_001019773.2

    Status: VALIDATED

    Source sequence(s)
    AK147410, AK147612, CJ125191
    Consensus CDS
    CCDS56867.1
    UniProtKB/Swiss-Prot
    Q3UH33, Q3UHG1, Q80U49, Q80UM2
    Related
    ENSMUSP00000098580.4, ENSMUST00000101018.11
    Conserved Domains (2) summary
    pfam00498
    Location:2389
    FHA; FHA domain
    pfam15308
    Location:8321510
    CEP170_C; CEP170 C-terminus
  2. NM_001412902.1NP_001399831.1  centrosomal protein of 170 kDa protein B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC124353
    UniProtKB/TrEMBL
    B9EIX2
    Related
    ENSMUSP00000152143.2, ENSMUST00000220627.2

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000078.7 Reference GRCm39 C57BL/6J

    Range
    112687950..112713026
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006515766.5XP_006515829.1  centrosomal protein of 170 kDa protein B isoform X1

    See identical proteins and their annotated locations for XP_006515829.1

    UniProtKB/Swiss-Prot
    Q3UH33, Q3UHG1, Q80U49, Q80UM2
    Conserved Domains (2) summary
    pfam00498
    Location:2389
    FHA; FHA domain
    pfam15308
    Location:8321510
    CEP170_C; CEP170 C-terminus