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Unc79 unc-79 homolog [ Mus musculus (house mouse) ]

Gene ID: 217843, updated on 9-May-2024

Summary

Official Symbol
Unc79provided by MGI
Official Full Name
unc-79 homologprovided by MGI
Primary source
MGI:MGI:2684729
See related
Ensembl:ENSMUSG00000021198 AllianceGenome:MGI:2684729
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Mlca3; 9030205A07Rik
Summary
Acts upstream of or within behavioral response to ethanol. Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human UNC79 (unc-79 homolog, NALCN channel complex subunit). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in CNS E18 (RPKM 7.5), whole brain E14.5 (RPKM 7.5) and 7 other tissues See more
Orthologs
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Genomic context

See Unc79 in Genome Data Viewer
Location:
12 E; 12 52.68 cM
Exon count:
53
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (102913642..103150487)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (102947383..103184228)

Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene BTB domain containing 7 Neighboring gene STARR-positive B cell enhancer ABC_E8503 Neighboring gene ribosomal protein S2 pseudogene Neighboring gene cytochrome c oxidase subunit 8C Neighboring gene STARR-seq mESC enhancer starr_33121 Neighboring gene proline rich membrane anchor 1 Neighboring gene STARR-positive B cell enhancer ABC_E7173 Neighboring gene family with sequence similarity 181, member A Neighboring gene predicted gene 29508

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • KIAA1409

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
protein unc-79 homolog
Names
modifier of locomotor activity 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081017.2NP_001074486.2  protein unc-79 homolog

    See identical proteins and their annotated locations for NP_001074486.2

    Status: VALIDATED

    Source sequence(s)
    AC122367, AC151982, AC165074
    Consensus CDS
    CCDS49149.2
    UniProtKB/Swiss-Prot
    Q0KK54, Q0KK59, Q6L9U9, Q8CCC5
    UniProtKB/TrEMBL
    E5CYJ9
    Related
    ENSMUSP00000098659.6, ENSMUST00000101099.12
    Conserved Domains (1) summary
    pfam14776
    Location:113645
    UNC-79; Cation-channel complex subunit UNC-79

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000078.7 Reference GRCm39 C57BL/6J

    Range
    102913642..103150487
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036157347.1XP_036013240.1  protein unc-79 homolog isoform X5

    UniProtKB/TrEMBL
    E5CYJ9
    Conserved Domains (1) summary
    pfam14776
    Location:114645
    UNC-79; Cation-channel complex subunit UNC-79
  2. XM_036157360.1XP_036013253.1  protein unc-79 homolog isoform X18

    UniProtKB/TrEMBL
    E5CYJ9
    Related
    ENSMUSP00000136332.2, ENSMUST00000179002.8
    Conserved Domains (1) summary
    pfam14776
    Location:61592
    UNC-79; Cation-channel complex subunit UNC-79
  3. XM_036157361.1XP_036013254.1  protein unc-79 homolog isoform X19

    UniProtKB/TrEMBL
    E5CYJ9
    Conserved Domains (1) summary
    pfam14776
    Location:47578
    UNC-79; Cation-channel complex subunit UNC-79
  4. XM_036157364.1XP_036013257.1  protein unc-79 homolog isoform X22

    UniProtKB/TrEMBL
    J3QNP0
    Related
    ENSMUSP00000136888.2, ENSMUST00000178076.8
    Conserved Domains (1) summary
    pfam14776
    Location:3468
    UNC-79; Cation-channel complex subunit UNC-79
  5. XM_036157365.1XP_036013258.1  protein unc-79 homolog isoform X23

    UniProtKB/TrEMBL
    J3QNP0
    Conserved Domains (1) summary
    pfam14776
    Location:6277
    UNC-79; Cation-channel complex subunit UNC-79
  6. XM_036157344.1XP_036013237.1  protein unc-79 homolog isoform X1

    UniProtKB/TrEMBL
    E5CYJ9
    Conserved Domains (1) summary
    pfam14776
    Location:141672
    UNC-79; Cation-channel complex subunit UNC-79
  7. XM_036157350.1XP_036013243.1  protein unc-79 homolog isoform X8

    UniProtKB/TrEMBL
    E5CYJ9
    Conserved Domains (1) summary
    pfam14776
    Location:141672
    UNC-79; Cation-channel complex subunit UNC-79
  8. XM_036157353.1XP_036013246.1  protein unc-79 homolog isoform X11

    UniProtKB/TrEMBL
    E5CYJ9
    Conserved Domains (1) summary
    pfam14776
    Location:141672
    UNC-79; Cation-channel complex subunit UNC-79
  9. XM_036157352.1XP_036013245.1  protein unc-79 homolog isoform X10

    UniProtKB/TrEMBL
    E5CYJ9
    Conserved Domains (1) summary
    pfam14776
    Location:141672
    UNC-79; Cation-channel complex subunit UNC-79
  10. XM_036157348.1XP_036013241.1  protein unc-79 homolog isoform X6

    UniProtKB/TrEMBL
    E5CYJ9
    Conserved Domains (1) summary
    pfam14776
    Location:141672
    UNC-79; Cation-channel complex subunit UNC-79
  11. XM_036157358.1XP_036013251.1  protein unc-79 homolog isoform X16

    UniProtKB/TrEMBL
    E5CYJ9
    Conserved Domains (1) summary
    pfam14776
    Location:141672
    UNC-79; Cation-channel complex subunit UNC-79
  12. XM_036157355.1XP_036013248.1  protein unc-79 homolog isoform X13

    UniProtKB/TrEMBL
    E5CYJ9
    Conserved Domains (1) summary
    pfam14776
    Location:141672
    UNC-79; Cation-channel complex subunit UNC-79
  13. XM_036157354.1XP_036013247.1  protein unc-79 homolog isoform X12

    UniProtKB/TrEMBL
    E5CYJ9
    Conserved Domains (1) summary
    pfam14776
    Location:88619
    UNC-79; Cation-channel complex subunit UNC-79
  14. XM_036157349.1XP_036013242.1  protein unc-79 homolog isoform X7

    UniProtKB/TrEMBL
    E5CYJ9
    Conserved Domains (1) summary
    pfam14776
    Location:141672
    UNC-79; Cation-channel complex subunit UNC-79
  15. XM_006515743.4XP_006515806.1  protein unc-79 homolog isoform X2

    UniProtKB/TrEMBL
    E5CYJ9
    Conserved Domains (3) summary
    pfam07964
    Location:16942015
    Red1; Rec10 / Red1
    pfam14776
    Location:141672
    UNC-79; Cation-channel complex subunit UNC-79
    cl02544
    Location:812873
    VHS_ENTH_ANTH; VHS, ENTH and ANTH domain superfamily
  16. XM_036157351.1XP_036013244.1  protein unc-79 homolog isoform X9

    UniProtKB/TrEMBL
    E5CYJ9
    Conserved Domains (1) summary
    pfam14776
    Location:141672
    UNC-79; Cation-channel complex subunit UNC-79
  17. XM_036157362.1XP_036013255.1  protein unc-79 homolog isoform X20

    UniProtKB/TrEMBL
    E5CYJ9
    Conserved Domains (1) summary
    pfam14776
    Location:141672
    UNC-79; Cation-channel complex subunit UNC-79
  18. XM_036157345.1XP_036013238.1  protein unc-79 homolog isoform X3

    UniProtKB/TrEMBL
    E5CYJ9
    Conserved Domains (1) summary
    pfam14776
    Location:141672
    UNC-79; Cation-channel complex subunit UNC-79
  19. XM_036157346.1XP_036013239.1  protein unc-79 homolog isoform X4

    UniProtKB/TrEMBL
    E5CYJ9
    Conserved Domains (1) summary
    pfam14776
    Location:141672
    UNC-79; Cation-channel complex subunit UNC-79
  20. XM_036157357.1XP_036013250.1  protein unc-79 homolog isoform X15

    UniProtKB/TrEMBL
    E5CYJ9
    Conserved Domains (1) summary
    pfam14776
    Location:141672
    UNC-79; Cation-channel complex subunit UNC-79
  21. XM_036157359.1XP_036013252.1  protein unc-79 homolog isoform X17

    UniProtKB/TrEMBL
    E5CYJ9
    Conserved Domains (1) summary
    pfam14776
    Location:141672
    UNC-79; Cation-channel complex subunit UNC-79
  22. XM_036157363.1XP_036013256.1  protein unc-79 homolog isoform X21

    UniProtKB/TrEMBL
    E5CYJ9
    Conserved Domains (1) summary
    pfam14776
    Location:141672
    UNC-79; Cation-channel complex subunit UNC-79
  23. XM_036157356.1XP_036013249.1  protein unc-79 homolog isoform X14

    UniProtKB/TrEMBL
    E5CYJ9
    Conserved Domains (1) summary
    pfam14776
    Location:88619
    UNC-79; Cation-channel complex subunit UNC-79

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_177621.2: Suppressed sequence

    Description
    NM_177621.2: This RefSeq was suppressed temporarily based on the calculation that the annotated protein was shorter than a protein or proteins from a putative ortholog.