U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Fam161b family with sequence similarity 161, member B [ Mus musculus (house mouse) ]

Gene ID: 217705, updated on 7-Apr-2025

Summary

Go to the top of the page Help
Official Symbol
Fam161bprovided by MGI
Official Full Name
family with sequence similarity 161, member Bprovided by MGI
Primary source
MGI:MGI:2443027
See related
Ensembl:ENSMUSG00000021234 AllianceGenome:MGI:2443027
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
9330169D17; 9830169C18Rik
Summary
Predicted to be involved in cilium organization. Predicted to be located in cytoplasmic microtubule. Predicted to colocalize with cilium. Orthologous to human FAM161B (FAM161 centrosomal protein B). [provided by Alliance of Genome Resources, Apr 2025]
Expression
Broad expression in CNS E18 (RPKM 4.6), CNS E14 (RPKM 4.6) and 22 other tissues See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Fam161b in Genome Data Viewer
Location:
12 D1; 12 39.17 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (84392088..84408633, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (84345309..84361860, complement)

Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E10765 Neighboring gene prostaglandin reductase 2 Neighboring gene zinc finger protein 410 Neighboring gene LSM6 homolog, U6 small nuclear RNA associated pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E1445 Neighboring gene coenzyme Q6 monooxygenase Neighboring gene ectonucleoside triphosphate diphosphohydrolase 5 Neighboring gene CapStarr-seq enhancer MGSCv37_chr12:85729760-85729947 Neighboring gene STARR-positive B cell enhancer ABC_E8493 Neighboring gene basal body orientation factor 1 Neighboring gene ring finger protein 113A2

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways. Sang L, et al. Cell, 2011 May 13. PMID 21565611, Free PMC Article
  2. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  3. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
  4. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
  5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in cilium organization IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cytoplasmic microtubule IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasmic microtubule ISO
Inferred from Sequence Orthology
more info
  
located_in microtubule cytoskeleton ISO
Inferred from Sequence Orthology
more info
  

General protein information

Go to the top of the page Help
Preferred Names
protein FAM161B

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001358283.2 → NP_001345212.1  protein FAM161B

    Status: VALIDATED

    Source sequence(s)
    AC120402, AC159649
    Consensus CDS
    CCDS26043.1
    UniProtKB/Swiss-Prot
    Q8BQX8, Q8BSL9, Q8CB59, Q8CBZ3
    Related
    ENSMUSP00000070407.3, ENSMUST00000065536.9
    Conserved Domains (1) summary
    pfam10595
    Location:168 → 535
    UPF0564; Uncharacterized protein family UPF0564

  2. NM_172581.4 → NP_766169.1  protein FAM161B

    See identical proteins and their annotated locations for NP_766169.1

    Status: VALIDATED

    Source sequence(s)
    AC120402, AC159649
    Consensus CDS
    CCDS26043.1
    UniProtKB/Swiss-Prot
    Q8BQX8, Q8BSL9, Q8CB59, Q8CBZ3
    Related
    ENSMUSP00000021659.2, ENSMUST00000021659.2
    Conserved Domains (1) summary
    pfam10595
    Location:168 → 535
    UPF0564; Uncharacterized protein family UPF0564

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000078.7 Reference GRCm39 C57BL/6J

    Range
    84392088..84408633 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036157324.1 → XP_036013217.1  protein FAM161B isoform X1

    Conserved Domains (1) summary
    pfam10595
    Location:168 → 529
    UPF0564; Uncharacterized protein family UPF0564

RNA

  1. XR_003950036.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8CB59.1 GenPept UniProtKB/Swiss-Prot:Q8CB59

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools