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Ankmy2 ankyrin repeat and MYND domain containing 2 [ Mus musculus (house mouse) ]

Gene ID: 217473, updated on 26-Sep-2022

Summary

Official Symbol
Ankmy2provided by MGI
Official Full Name
ankyrin repeat and MYND domain containing 2provided by MGI
Primary source
MGI:MGI:2144755
See related
Ensembl:ENSMUSG00000036188 AllianceGenome:MGI:2144755
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
ZMYND20
Summary
Enables enzyme binding activity. Predicted to be located in cilium. Is expressed in brain; spinal cord; tail dorsal root ganglion; and trigeminal ganglion. Orthologous to human ANKMY2 (ankyrin repeat and MYND domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E18 (RPKM 13.0), bladder adult (RPKM 11.8) and 27 other tissues See more
Orthologs
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Genomic context

See Ankmy2 in Genome Data Viewer
Location:
12; 12 A3
Exon count:
11
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (36207123..36247290)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (36157124..36197291)

Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene ubiquitin-conjugating enzyme E2F (putative) pseudogene Neighboring gene basic leucine zipper and W2 domains 2 Neighboring gene ribosomal protein S3A pseudogene Neighboring gene non-POU-domain-containing, octamer binding protein pseudogene Neighboring gene leucine rich repeat containing 72 Neighboring gene predicted gene, 40390 Neighboring gene predicted gene, 40392

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2)  1 citation
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC18754

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables enzyme binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
is_active_in cellular_component ND
No biological Data available
more info
 
located_in cilium IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
ankyrin repeat and MYND domain-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_146033.3NP_666145.3  ankyrin repeat and MYND domain-containing protein 2

    See identical proteins and their annotated locations for NP_666145.3

    Status: VALIDATED

    Source sequence(s)
    AK077556, AK164434, BF453918, BY069852
    Consensus CDS
    CCDS25885.1
    UniProtKB/Swiss-Prot
    Q3TPE9, Q921J1
    Related
    ENSMUSP00000039484.4, ENSMUST00000041640.5
    Conserved Domains (4) summary
    cd00204
    Location:30132
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam01753
    Location:320357
    zf-MYND; MYND finger
    pfam13857
    Location:3187
    Ank_5; Ankyrin repeats (many copies)
    sd00045
    Location:4577
    ANK; ANK repeat [structural motif]

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000078.7 Reference GRCm39 C57BL/6J

    Range
    36207123..36247290
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036157307.1XP_036013200.1  ankyrin repeat and MYND domain-containing protein 2 isoform X1

    Conserved Domains (3) summary
    sd00045
    Location:3668
    ANK; ANK repeat [structural motif]
    pfam01753
    Location:311348
    zf-MYND; MYND finger
    pfam12796
    Location:41123
    Ank_2; Ankyrin repeats (3 copies)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_178910.2: Suppressed sequence

    Description
    NM_178910.2: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.